
03/07/2025
Obesity not only affects metabolism and cardiovascular health but is also closely linked to the development of various types of cancer. Studies have shown that obesity increases the risk of breast, colorectal, liver, and pancreatic cancers through mechanisms involving chronic inflammation, insulin resistance, and endocrine imbalances. Adipose tissue secretes pro-inflammatory factors such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), creating an inflammatory microenvironment that promotes tumor growth. Additionally, excessive visceral fat can elevate estrogen levels, increasing the risk of breast and endometrial cancers.
A sedentary lifestyle also poses significant health risks. Prolonged sitting reduces basal metabolic rate, increases insulin resistance, and promotes fat accumulation, leading to obesity-related diseases. Research indicates that individuals who sit for more than six hours per day have a significantly higher risk of developing metabolic syndrome, cardiovascular diseases, and certain cancers. Moreover, obesity and prolonged sitting can negatively impact skin health, accelerating skin aging, causing hyperpigmentation, and increasing the incidence of inflammatory skin conditions.
Therefore, adopting a healthier lifestyle is crucial. Increasing physical activity, reducing sedentary time, and maintaining a balanced diet can help lower the risk of obesity and its associated diseases, ultimately protecting overall health.