Bryce Moore, NMD

08/20/2024

Over half of Americans aren't getting enough Magnesium.

A recent study has found that individuals with low magnesium levels also exhibit higher DNA damage in their blood cells, potentially leading to mutations that cause cancer.

Magnesium is important for cancer prevention. In a study involving 66,000 people, researchers found that each 100 mg drop in daily magnesium intake bumped up the risk of pancreatic cancer by 24%.

Why is magnesium critical? It helps maintain the function of DNA repair enzymes. These enzymes are essential because they repair DNA damage and prevent mutations that could lead to cancer.

Studies document that magnesium is inversely associated with the risk of diabetes, which is a risk factor of pancreatic cancer. However, studies on the direct association of magnesium with pancreatic cancer are few and findings are inconclusive. In this ...

08/19/2024

According to 3 different analyses of the data:

Women with vitamin D level of 60 ng/ml or greater have an 80% lower risk of breast cancer compared to those with a vitamin D level of 20 ng/ml or less

Background While numerous epidemiologic studies have found an association between higher serum 25-hydroxyvitamin D [25(OH)D] concentrations and lower breast cancer risk, few have assessed this association for concentrations >40 ng/ml. Objective To investigate the relationship between 25(OH)D concent...

08/19/2024

150 minutes of moderate-intensity exercise per week can lower your risk of Alzheimer's by as much as 33%

Plus, a Cleveland Clinic neuropsychologist shares a fun way to implement it.

08/19/2024

New research has found that six months of high-intensity interval training (HIIT) can boost your cognitive function and keep it high for five years. We've known that physical activity can protect brain health, but the duration of the benefits is remarkable. For those with cardiovascular disease, please work up to this carefully.

Consistency pays

07/24/2024

I am so excited and proud to announce I am now a practitioner for Cape Wellness Collaborative, a non-profit organization that provides free of cost integrative wellness therapies to anyone on Cape Cod and the Islands facing cancer. I am the first naturopathic medical doctor affiliated with CWC!

Current CWC members can utilize my services, free of cost, by making an appointment on my website:

brycemoorenmd.com

https://www.capewellness.org/wellness-therapies-2/moore

Find a wellness therapy practitioner through Cape Wellness Collaborative's interactive directory

02/16/2024

01/30/2024

With any type of cancer, industrial pollutant exposure needs to be considered and addressed in treatment.

Not only is glyphosate directly carcinogenic, it is a neurotoxin, nephrotoxin, GI toxin, and significantly disrupts our microbiome.

Glyphosate is most notably associated with blood and lymph cancers, including Acute Myeloid Leukemia and Non-Hodgkin's Lymphoma.

All synthetic pesticides should be suspect.

A Pennsylvania jury handed down a $2.25 billion verdict against Monsanto and its parent company, Bayer, after determining its Roundup herbicide product caused a man’s cancer, the plaintiff’s lawyers announced.

01/09/2024

💚🌱💪 Go get organized with those seeds! https://gardentabs.com/saving-seeds-in-envelopes/

12/14/2023

Beyond healing, You can experience a life of abundant health, joy and wellness.

anoasisofhealing.com

12/11/2023

𝐌𝐊𝟒 𝐟𝐨𝐫 𝐌𝐲𝐞𝐥𝐨𝐝𝐲𝐬𝐩𝐥𝐚𝐬𝐭𝐢𝐜 𝐒𝐲𝐧𝐝𝐫𝐨𝐦𝐞 𝐚𝐧𝐝 𝐀𝐜𝐮𝐭𝐞 𝐌𝐲𝐞𝐥𝐨𝐢𝐝 𝐋𝐞𝐮𝐤𝐞𝐦𝐢𝐚

Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are both hematopoietic stem cell disorders characterized by trilineage cytopenias from bone marrow failure. Trilineage cytopenias include low red blood cells, white blood cells, and platelets. Patients present with normocellular or hypercellular bone marrow, and increased blast cells. Blast cells are immature white blood cells that precede granulocyte development (neutrophils, basophils, eosinophils, macrophages, dendritic cells). MDS is a condition pre-leukemia that can progress to AML, and currently has no routine course of care. AML is diagnosed when bone marrow aspirate shows ≥ 20% blast cells. In normal bone marrow blast count is below 5%, MDS presents between 5 and 20%, and AML above 20%.
Clinical presentation of MDS and AML may include symptoms of fatigue, shortness of breath, pallor, easy bruising or bleeding, petechiae, frequent infections, arthralgia, and myalgia. Laboratory findings may include elevated white blood cells, normocytic anemia, thrombocytopenia, neutropenia, disseminated intravascular coagulation, and blasts in peripheral blood. The vast majority of cases have an unidentifiable cause but benzene, smoke, and radiation exposure are significant risk factors. Over 80% of MDS patients are older than 60 years of age and up to 20% of all AML diagnoses are attributed to treatments from other types of cancer (t-AML).
Cytarabine is the standard treatment for AML and can create complete remission in 65-75% of patients between 18-60 years old. Unfortunately, 50-70% of the remission cases relapse within 3 years. The average time to death for AML is 1 year, and 3 year overall survival in MDS is just 45%. Treatment related t-MDS/t-AML median survival is just 8 months.
Dr. Neustadt discusses the use of MK4, a subtype of vitamin K2, for the treatment of MDS and AML. Vitamin K1 is found in plants, converted to MK4 in humans, and accumulates in breast, te**es, pancreas, brain, and arterial wall tissue. Several human studies have shown vitamin K treatment to be extremely safe. Over 6,000 patients administered MK4 for up to 8 years had no serious side effects, even in those with liver cirrhosis, myelofibrosis, and kidney failure on dialysis. MK4 has been used as medication in Japan for over 20 years, most notably for osteoporosis, hemorrhage, and hypoprothrombinemia.
In a prospective, randomized clinical trial of 18 MDS patients with a mean age of 72 years old, one group was administered 45 mg of oral MK7 per day while the other group had no intervention. Treatment duration lasted 16 weeks and patients were followed up for 34 months after. Based on IWG-2000 criteria, 5 out of 9 patients in the treatment group improved, while only 1 of 9 patients improved in the none treatment group. Notably, 𝐧𝐨 𝐨𝐧𝐞 𝐢𝐧 𝐭𝐡𝐞 𝐌𝐊𝟒 𝐠𝐫𝐨𝐮𝐩 𝐩𝐫𝐨𝐠𝐫𝐞𝐬𝐬𝐞𝐝 𝐭𝐨 𝐚𝐜𝐮𝐭𝐞 𝐥𝐞𝐮𝐤𝐞𝐦𝐢𝐚. Absolute neutrophil counts were significantly higher in the treatment group with a mean increase of 162% and a major response in 3 of 9 patients. The investigators also found a statistically significant increase in hemoglobin and platelets. Perhaps most impressive – after 3 years, five patients in the MK4 group remained in good hematologic condition, showed no signs of toxicity, and none of them progressed to AML.

Dr. Neustadt reviewed the more than 20 years of medical research on myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) and the potential for nat...

12/10/2023

𝐒𝐭𝐫𝐞𝐭𝐜𝐡𝐢𝐧𝐠, 𝐂𝐨𝐧𝐧𝐞𝐜𝐭𝐢𝐯𝐞 𝐓𝐢𝐬𝐬𝐮𝐞, 𝐂𝐡𝐫𝐨𝐧𝐢𝐜 𝐏𝐚𝐢𝐧, 𝐚𝐧𝐝 𝐂𝐚𝐧𝐜𝐞𝐫

Dr. Helene Langevin is director of the National Center for Complementary and Integrative Health. She oversees the governments lead agency for research on science, usefulness, and safety of integrative health approaches and their role in health care. Before joining the National Institutes of Health (NIH), she was director of the Osher Center for Integrative Medicine in Boston, Massachusetts. Her research has focused on the role of biomechanical forces on connective tissue fibrosis, chronic musculoskeletal pain, immunology, and cancer. Dr. Langevin is a renowned expert on the science of yoga, acupuncture, and massage therapy.
While evaluating thoracolumbar fascia she saw thicker, more disorganized fascia in patients with low back pain (LBP). With further examination, her team found LBP patients had reduced shear plane motion associated with greater tissue adhesion. Adhesions occur from chronic chemical or physical injury and persistent inflammation. Over time, fibrosis, connective tissue stiffness, and pain set in. This can cause greater restrictions in movement and fear of reproducing or worsening the pain. It becomes a vicious cycle; with less localized movement, stiffness and fibrosis worsen. Connective tissue needs movement to function properly, and I suspect this has a major impact on immune current.
Similar to unhealthy soil, Dr. Langevin suggests that cancer cells arise from a bed of dense connective tissue, otherwise known as the tumor stroma. Desmoplastic reactions in surrounding tissue cause disorganized protein aggregates, fibrosis, and adhesions, supporting cancer cell metastasis and worsening patient prognosis. While inflammation and fibrosis are independent predisposing factors for cancer growth, tumors themselves secrete tissue-stiffening molecules.
With that in mind, they investigated the effect of stretching on breast cancer tumor growth in mice. Her group established a protocol for stretching mice, where they are gently held by the tail and lifted while front paws grasp a bar – a novel experimental mechanism for rodents. The stretch group held this position 10 minutes per day for 4 weeks. 𝐒𝐭𝐫𝐞𝐭𝐜𝐡𝐞𝐝 𝐦𝐢𝐜𝐞 𝐡𝐚𝐝 𝐬𝐢𝐠𝐧𝐢𝐟𝐢𝐜𝐚𝐧𝐭𝐥𝐲 𝐬𝐥𝐨𝐰𝐞𝐫 𝐭𝐮𝐦𝐨𝐫 𝐠𝐫𝐨𝐰𝐭𝐡 𝐟𝐫𝐨𝐦 𝐰𝐞𝐞𝐤𝐬 𝟐-𝟒 𝐚𝐧𝐝 𝐭𝐮𝐦𝐨𝐫 𝐯𝐨𝐥𝐮𝐦𝐞 𝐰𝐚𝐬 𝟓𝟐% 𝐬𝐦𝐚𝐥𝐥𝐞𝐫 than the non-stretch group. Programmed Death Receptor-1, a marker of T-cell exhaustion and compromised immunity, was lower in CD8+ T-cells of stretched mice. In addition, specialized pro-resolving mediators RvD1 and RvD2 were significantly greater in the stretch group.

Dr. Helene Langevin explains the importance of connective tissue in the body and its link to the immune system. She talks about recent findings on the effect...

12/05/2023

𝐒𝐚𝐮𝐧𝐚 𝐇𝐢𝐬𝐭𝐨𝐫𝐲 𝐚𝐧𝐝 𝐈𝐦𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐟𝐨𝐫 𝐍𝐨𝐧-𝐜𝐨𝐦𝐦𝐮𝐧𝐢𝐜𝐚𝐛𝐥𝐞 𝐃𝐢𝐬𝐞𝐚𝐬𝐞

Sauna originated approximately 4,000 years ago in northern Europe, predating contemporary organized religion. The first saunas were caves heated by fire and draped with animal skin. Primordial man used the thermal capacity of stone to prolong the heat source through a cold night. During winter, these hot rooms were one of the only habitable places. Still, saunas have been used for more than simply keeping warm – they are bathhouses, sanctuaries, and places of worship. In Finland, nearly everyone takes a sauna at least once a week to cleanse the physical and mental bodies. Despite esoteric jargon, there are measurable physiologic benefits of hyperthermic therapy that will become invaluable in treatment of modern non-communicable diseases.

Thermoregulation and immunity are inherently inseparable phenomena. As body temperature rises, our nervous system stimulates dilation of blood vessels, encouraging movement of white blood cells. During infection, body temperature rises because white blood cells function best over 100 degrees Fahrenheit. Fever alters surface proteins on Lymphocytes to facilitate mobility through blood vessels, known as lymphocyte trafficking. I cannot understate the importance of vessel compliance and blood flow efficiency. Heat promotes movement in tissue throughout the body entirely including lymph, cerebrospinal fluid, the gastrointestinal tract, and, the vital organs. Our liver is constantly working to remove unwanted substances from blood by increasing their polarity, and therefore how readily they will travel with water. This process is done primarily through hydrolysis and conjugation, increasing polarity and solubility in water.

Sauna bathing is consistently studied in Finland as an enriching habit for heart and cardiovascular function. Laukkanen et al. literally investigated the association of sauna frequency with risk of sudden cardiac death (SCD), fatal coronary heart disease (CHD), fatal cardiovascular disease (CVD), and all-cause mortality. 2315 middle-aged (42-60 years) men from Eastern Finland were followed for an average of 20 years. They found sauna frequency is inversely associated with cardiovascular disease and all-cause mortality. Sauna improves detoxification of several persistent organic pollutants and heavy metals (mercury, arsenic, lead, cadmium) linked to cardiovascular disease, diabetes, and obesity. Furthermore, strong evidence suggests sauna bathing can significantly improve the effect certain chemotherapies and antidepressant medication.
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Sears ME, Kerr KJ, Bray RI. Arsenic, cadmium, lead, and mercury in sweat: a systematic review. J Environ Public Health. 2012;2012:184745. doi:10.1155/2012/184745

Laukkanen, T., Kunutsor, S.K., Khan, H. et al. Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study. BMC Med 16, 219 (2018). https://doi.org/10.1186/s12916-018-1198-0

Laukkanen T, Khan H, Zaccardi F, Laukkanen JA. Association between sauna bathing and fatal cardiovascular and all-cause mortality events. JAMA Intern Med. 2015 Apr;175(4):542-8. doi: 10.1001/jamainternmed.2014.8187. PMID: 25705824.

Rentscher, Kelly; Janssen, Clemens W.; Lowry, Christopher A.; Mehl, Matthias R.; Allen, John J. B.; Kelly, Kimberly L., et al. (2016). Whole-Body Hyperthermia For The Treatment Of Major Depressive Disorder JAMA Psychiatry 73, 8.

Background Previous evidence indicates that sauna bathing is related to a reduced risk of fatal cardiovascular disease (CVD) events in men. The aim of this study was to investigate the relationship between sauna habits and CVD mortality in men and women, and whether adding information on sauna habit...