02/17/2025
Women, do you feel your Elvanse/Vyvanse wears off quickly? There’s a reason!!
Overall, women tend to metabolise Elvanse faster than men.
Absorption of Elvanse generally similar between men and women, but slight alterations in GI motility and blood flow, slightly influence the rate at which Elvanse enters the bloodstream in women.
Since women have less lean body mass per kg of body weight, the drug is distributed into a smaller water-rich volume in women, resulting in higher peak plasma concentrations and faster clearance.
Women have less drug exposure of Elvanse from the moment it enters our system to when it leaves due to how fast it’s absorbed and metabolised.
I’ll be doing a video on my theories on how to potentially manage this!