Stream Community Engagement

06/30/2021

Many lessons were learned about community engagement in the . CABs documented their experiences with CE and developed practical recommendations designed to improve community engagement in future clinical trials.

To read the practical recommendations from CE in the STREAM clinical trial, click here: https://streamrecommendations.treattb.org/

To read Community Engagement Lessons Learned: A Community Perspective, click here: https://www.vitalstrategies.org/resources/community-engagement-lessons-learned-a-community-perspective/

USAID - US Agency for International Development
Vital Strategies International Union Against Tuberculosis and Lung Disease (The Union)
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STREAM is a multi-country clinical trial evaluating shorter, more tolerable regimens for multidrug-resistant tuberculosis. This site offers practical recommendations drawn from the lessons learned over the course of the trial.

04/01/2021

For , the Community Advisory Board in Chennai, India released a documentary on the importance of community engagement in TB research. To view the documentary, click here:

https://treattb.org/2021/04/01/chennai-stream-cab-releases-documentary-on-world-tb-day/

USAID - US Agency for International Development Vital Strategies International Union Against Tuberculosis and Lung Disease (The Union)

01/27/2021

All participants have now completed their allocated trial treatment, paving the way for preliminary trial results to be reported in 2022. Thank you to our implementing partners and trial participants, who played a critical role in achieving this important milestone. USAID - US Agency for International Development Vital Strategies Medical Research Council

Last week, the STREAM clinical trial reached a significant milestone, when the last-recruited participant completed their allocated trial treatment regimen. A total of 588 participants at 13 sites were recruited to Stage 2 of the trial, which is expected to report results in 2022. The aim of Stage 2...

12/24/2020

A great initiative by our colleagues in Mongolia who recently organized an online discussion on managing TB during COVID. https://www.facebook.com/CABMongol/posts/212071097081685?notif_id=1608698953285799¬if_t=page_tag&ref=notif

12/23/2020

Last month, STREAM Community Advisory Boards (CABs) from seven countries joined the eighth STREAM All-CAB webinar to learn more about ethical principles related to research, and their impact on the roles and responsibilities of key stakeholders. The webinar focused on how communities can ensure thei...

10/22/2020

Subrat Mohanty, India’s Community Engagement Coordinator for the , will be leading the Community Connect on "TB Champions respond to COVID-19: Narratives from India" tomorrow from 11:30-12:15 CEST. To join the session, please click here: https://worldlunghealth2020.theunion.org/session/tb-champions-respond-to-covid-19-narratives-from-india

USAID - US Agency for International Development The Union World Conference on Lung Health Medical Research Council

The COVID-19 pandemic limited access to TB services across India. This was reflected in Nikshay data, media reporting and reports by TB advocates showing that TB case notification had declined considerably and loss to follow up cases had surged. COVID-19 presented new challenges for healthcare provi...

10/22/2020

In Stage 1 of the , severe QT prolongation was more frequent on the short regimen. This could have been due to high dose moxifloxacin and clofazamine used in the short regimen. At the conference, Gareth Hughes from Medical Research Council reported the results of further analyses of Stage 1 data to explore whether there was a cut-off value that could allow prioritization of ECG monitoring. Results suggest that using a combination of cut-offs might permit a reduction in ECG monitoring frequency in 47% of patients on the short regimen. These results need further validation but could potentially be useful in programmatic settings with limited resources.
USAID - US Agency for International Development The Union World Conference on Lung Health

10/22/2020

Vital Strategies’ team investigated the sensitivity and specificity of tablet-based audiometry compared to conventional audiometry in Stage 2 of the . Vital Strategies’ Pharmacist, Ishmael Qawiy, presented a poster on our findings, which suggested tablet-based audiometry was a sensitive tool for detecting hearing loss and an effective way to monitor clinical trial participants. Tablet-based technology is important for improving access to audiometry testing in low resource settings and should be considered in settings where conventional audiometry is limited or unavailable. USAID - US Agency for International Development The Union World Conference on Lung Health Medical Research Council

10/22/2020

At the , Laura Rosu, partner and researcher from LSTM, reported that the short-regimen for MDR-TB evaluated in Stage 1 of the reduced health system costs by 20–25%, and was associated with an earlier return to work and a reduction in the purchase of supplementary food. The results also indicate that men spent more on supplementary food than women in both arms of the trial. This disparity should be considered by policy makers when devising packages to address TB patient costs. USAID - US Agency for International Development The Union World Conference on Lung Health Medical Research Council

10/22/2020

Vital Strategies Ishmael Qawiy presents data on tablet-based audiometry compared to conventional audiometry in Stage 2 of the . Head to the portal to hear his presentation! USAID - US Agency for International Development The Union World Conference on Lung Health Medical Research Council

*Please scroll down for more information* 12:30 - 12:35: Introduction 12:35 - 12:43: OA-17-605-22-Audiometry outcomes during and after drug-resistant TB treatment with a kanamycin-containing drug-regimen: drug-resistant TB patients assessed in three rural districts of Masvingo Zimbabwe The abstract....