The Children's Hospital of Philadelphia Research Institute

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The Children's Hospital of Philadelphia Research Institute

CHOP Research advances the health of children by turning scientific discovery into medical innovation
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09/02/2025

Dr. Laura Adang, a Children's Hospital of Philadelphia attending physician, and her team are well on their way to building the world’s largest database for metachromatic leukodystrophy (MLD). A rare, progressive disease, MLD often leads to children quickly losing the ability to walk and talk and is usually fatal within 10 to 20 years of diagnosis. Designed to help clinicians more quickly detect MLD, the MLD-Core Project builds on nearly a decade of work at CHOP’s Leukodystrophy Center and will harmonize lifelong medical record data from patients at centers around the country.

Learn more in a new Cornerstone story: http://ms.spr.ly/6184sd5fq

08/28/2025

Collaborating with institutions across the country, Children's Hospital of Philadelphia researchers conducted the largest comparative effectiveness trial to date for managing kidney stones in children. In a new Cornerstone story, learn about their findings and how they will help patients and families make informed decisions: http://ms.spr.ly/6181sw1Xc

08/26/2025

Don't miss this video from our friends at the Center for Injury Research and Prevention at CHOP, as 2025 Injury Science REU interns answer the question "Looking back, what stands out the most from your internship experience at Children's Hospital of Philadelphia?" Learn more below 👇

08/25/2025

When preterm babies have trouble breathing at birth, clinicians often turn to positive pressure ventilation to help fill the newborn’s lungs with air. In new research published in JAMA Pediatrics, Children's Hospital of Philadelphia researchers provide an evidence-based target for achieving effective lung aeration during delivery room resuscitation for preterm neonates. Learn more in a new Snapshot Science blog: http://ms.spr.ly/6182skQOG

08/22/2025

In the coming months, Children's Hospital of Philadelphia Research Institute will welcome its newest research facility, the 17-story, 350,000 square-foot Morgan Center for Research and Innovation, situated next to Philadelphia's iconic Schuylkill River. To celebrate this exciting new milestone, our latest Bench to Bedside podcast series features conversations with the staff and faculty intimately involved in the Morgan Center's development and design. In the first episode, available now, host Dr. Susan Furth chats with Donald Moore, senior vice president of CHOP's Real Estate, Facilities, and Operations, about what the Philadelphia community can look forward to when the Morgan Center opens.

🎧 Listen to the full episode now: http://ms.spr.ly/6181sXECd

08/21/2025

What do cortical circuits and comedians have in common? Well, not much until you meet Kierra Perry — a resource coordinator by day in the Division of Neurology at CHOP, and a stand-up comedian by night. After spending hours in the lab supporting clinical, research, and administrative activities, Perry harnesses her one-liners and whimsy (recently honed at an NYC-based clown school) to make audiences across Philadelphia laugh.

“When you tell a joke, even if it's a stupid joke — like, a one-liner that is just silly — and you make a huge room full of people all laugh at once … it's like magic,” Perry said. “There’s a ‘pop!’ that happens in the room, and suddenly, everybody is one, collective thing.”

Read our latest Cornerstone story now: http://ms.spr.ly/6185spglV

08/19/2025

How do Children's Hospital of Philadelphia researchers find balance out of the lab? For bioinformatician Dr. Hongbo Michael Xie, who celebrates his 18th work anniversary at CHOP this year, it’s traversing hiking trails around the United States.

“I will never forget the beautiful views or the beautiful hearts of the people I’ve met along the way,” Dr. Xie said in an Off Campus Cornerstone story.

Read the full story now on Cornerstone: http://ms.spr.ly/6187spgfD

08/18/2025

In this guest blog, Dr. Rachel Myers, associate director of our Center for Injury Research and Prevention at CHOP, writes about two new studies examining the value and long-term effectiveness of the CHOP Violence Intervention Program (VIP), which bridges the hospital to the community. VIP is one of the most established pediatric Violence Intervention Programs in the country, conducting innovative work that addresses the unique needs of pediatric patients and families affected by violent injury.

Read the full blog now on Cornerstone: http://ms.spr.ly/6188spgWo

08/14/2025

Summer interns in the Advancing Representation in Research Administration (ARRA) Program celebrated their work with a graduation ceremony surrounded by their Children's Hospital of Philadelphia mentors and colleagues! The program introduces undergrads and recent grads to rewarding careers in research administration. Congrats to Serafina Peluso (Research Creative Services), Jeanette Kim (Office of Faculty Development), Jade Jones (Research Project Management Office), J'Anna Curtis (Office of Faculty Development), and Claude Francois (Office of Tech Transfer & Innovation). Learn more about ARRA: http://ms.spr.ly/6180sr1Ow

08/12/2025

We’re proud to launch the I ❤ CHOP Run, Walk & Virtual Challenge, presented by Insurance Companies with Philadelphia Eagles running back, Saquon Barkley, as our Official Champion! This 5k run/3k walk is for everyone who hearts Children's Hospital of Philadelphia and together we'll raise vital funds for CHOP's greatest needs. The event will take place on April 26, 2026, at FDR Park – or you can participate virtually all May long.

Watch how we chose our #1 pick ⬇️ and learn more: http://ms.spr.ly/6184suene.

08/01/2025

Anemia of inflammation (AI), which develops after chronic disease or infection, is the most common type of anemia among hospitalized and chronically ill patients. While no targeted treatments for AI are currently available, new research from Children's Hospital of Philadelphia elucidates the recovery role of a chemical messenger, or cytokine, called tumor necrosis factor alpha (TNFα) for AI.

“Understanding the role of TNFα may open the door for the development of newer, safer therapies or combination approaches to treat autoimmune disorders,” said the study’s lead author, Dr. Amarilis Guerra.

Read more about this research in a new Snapshot Science blog post: http://ms.spr.ly/6189sJx99

07/31/2025

Happy National Intern Day to our Children's Hospital of Philadelphia Research Institute summer students! On this day, join us in recognizing the talent, passion, and contributions of the 2025 scholars in our CHOP-RISES, CRISSP, ARRA, and REU programs. Read a brief description of each research internship below, or click this link to learn more about gaining a unique internship experience at CHOP Research Institute: http://ms.spr.ly/6189sJxdh

▫️ CHOP-RISES: The CHOP Research Internship for Scholars and Emerging Scientists is a two-summer STEM-M internship designed to empower local high school students.

▫️ ARRA: The Advancing Representation in Research Administration (ARRA) Program introduces undergraduate students and recent grads to rewarding careers in research administration through practical training within various areas of research admin at CHOP.

▫️ CRISSP: The CHOP Research Institute Summer Scholars Program (CRISSP) is a 10-week summer internship for undergraduates interested in research related to child health and wellness.

▫️ REU: The Research Experiences for Undergraduate (REU) program is a 10-week internship offering students one-on-one mentorship from leading scientists and more hands-on research experience.

Address

3400 Civic Center Blvd
Philadelphia, PA
19104

Website

http://www.research.chop.edu/

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