ECOG-ACRIN Cancer Research Group

ECOG-ACRIN Cancer Research Group Biomarker-driven research involving adults who have or are at risk of developing cancer

Clinical study EA3191 is testing a new treatment approach for patients with squamous cell carcinoma of the head and neck...
01/29/2026

Clinical study EA3191 is testing a new treatment approach for patients with squamous cell carcinoma of the head and neck (HNSCC) that has come back after initial therapy. Learn more: https://bit.ly/ea3191-study

Dr. Seth Pollack of  is leading EA7222, a randomized phase 3 trial of doxorubicin alone or in combination with pembroliz...
01/28/2026

Dr. Seth Pollack of is leading EA7222, a randomized phase 3 trial of doxorubicin alone or in combination with pembrolizumab in patients with advanced UPS and related poorly differentiated sarcomas. More here: https://bit.ly/EA7222

In the   Study, researchers are testing if genetically-matched drug combinations will be more effective than single drug...
01/28/2026

In the Study, researchers are testing if genetically-matched drug combinations will be more effective than single drugs for certain patients with . Learn more: http://bit.ly/ComboMATCH

Honored that our partnership w/ Caris Life Sciences to improve recurrence risk assessment in early-stage   made MedCity ...
01/28/2026

Honored that our partnership w/ Caris Life Sciences to improve recurrence risk assessment in early-stage made MedCity News' Five Collaboration Trends That Shaped in 2025. View the full list:

Relationships between health systems, non profits, universities and public agencies are not new. The difference here is a nuance, the structure of the relationships are what stands out in these collaborations.

Patients with aggressive B-cell lymphoma that has recurred or is resistant to treatment may be eligible to participate i...
01/27/2026

Patients with aggressive B-cell lymphoma that has recurred or is resistant to treatment may be eligible to participate in clinical trial EA4231. Learn more here: https://bit.ly/EA4231

Clinical trial EA8192 aims to find out if treatment with durvalumab and chemotherapy can improve outcomes for patients w...
01/27/2026

Clinical trial EA8192 aims to find out if treatment with durvalumab and chemotherapy can improve outcomes for patients with high grade upper tract urothelial cancer prior to nephroureterectomy. https://bit.ly/ea8192-trial

Relief for the   community: the House’s FY26 spending bill boosts NIH by $415M and NCI by $128M, despite earlier threats...
01/26/2026

Relief for the community: the House’s FY26 spending bill boosts NIH by $415M and NCI by $128M, despite earlier threats of sharp funding cuts. Next step: the bill heads to the Senate. Read more via The Cancer Letter:

The U.S. House of Representatives Jan. 22 passed a three-bill minibus package that is expected to be the grand finale of the drama of the fiscal year 2026 appropriations process. The package, which funds the HHS as well as the departments of Defense, Transportation, Housing and Urban Development, La...

ComboMATCH Treatment Trial E5, led by Kristen Spencer, DO, MPH  of NYU Langone Health and Dustin Deming, MD of UW Health...
01/26/2026

ComboMATCH Treatment Trial E5, led by Kristen Spencer, DO, MPH of NYU Langone Health and Dustin Deming, MD of UW Health l Carbone Cancer Center, is a randomized phase 2 study of sotorasib with or without panitumumab in advanced solid tumors. Learn more here: https://bit.ly/combomatch-e5

Can patients with high-risk retroperitoneal   benefit from neoadjuvant chemotherapy? The international EA7211/STRASS 2  ...
01/26/2026

Can patients with high-risk retroperitoneal benefit from neoadjuvant chemotherapy? The international EA7211/STRASS 2 , led in the US by Dr. Kenneth Cardona, aims to find out. More: https://bit.ly/EA7211

EA1241, led by Dr. Joseph Sparano of The Mount Sinai Hospital, is a companion study for patients who previously took par...
01/26/2026

EA1241, led by Dr. Joseph Sparano of The Mount Sinai Hospital, is a companion study for patients who previously took part in either the TAILORx (PACCT-1) or RxPONDER (S1007) breast cancer trials. Learn more: https://bit.ly/EA1241

📢Calling for investigators &   professionals to join the upcoming webinar for EA1241, a companion   study for pts previo...
01/23/2026

📢Calling for investigators & professionals to join the upcoming webinar for EA1241, a companion study for pts previously enrolled in TAILORx or RxPONDER. Register below!

📅Feb 4 | 4 PM ET
🎙 Joseph Sparano, MD, Kevin Kalinsky, MD, MS, & Rima Patel, MD
🔗https://bit.ly/EA1241webinar

The MM1OA-EA02 clinical study is testing a new treatment approach for patients with acute myeloid leukemia who are age 6...
01/23/2026

The MM1OA-EA02 clinical study is testing a new treatment approach for patients with acute myeloid leukemia who are age 60 or older. Learn more: https://bit.ly/mm1oa-ea02-study

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+12157893631

Website

http://linktr.ee/ecog_acrin

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Our Story

We design and conduct cancer clinical trials, which are available to patients at nearly 1,200 member cancer centers and community hospitals in the US and internationally. We focus our research on adults who have or are at risk of developing cancer. The group is dedicated to achieving advances in all aspects of cancer care across all types of cancer. Our goal is to reduce the burden of cancer and improve the quality of life and survival in patients. Our primary source of funding is the National Cancer Institute, part of the National Institutes of Health.