Addario Lung Cancer Medical Institute - ALCMI

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Addario Lung Cancer Medical Institute - ALCMI

We fund and support investigator-led lung cancer clinical trials.

03/21/2026

Researchers at Novant Health have found that delaying immunotherapy initiation in extensive-stage small cell lung cancer does not compromise survival outcomes, offering a clinically meaningful insight for patients who require emergent hospitalization at diagnosis.

BACKGROUND: Extensive-stage small cell lung cancer (ES-SCLC) is an aggressive form of lung cancer associated with poor prognosis, and treatment goals are focused on prolonging survival and symptom palliation. Recent phase 3 trials have led to the approval of immunotherapy in the frontline setting fo...

03/20/2026

Researchers at the University of Gothenburg have uncovered a key molecular driver of lung cancer metastasis in older patients.

Lung tumors often grow more slowly but are more likely to spread to other organs, a pattern linked to increased activity of the protein ATF4.

03/19/2026

Whoa! This is big. Researchers at UVA Health have identified a direct link between severe respiratory viral infections and increased lung cancer risk.

A severe case of COVID-19 or influenza could increase the risk of lung cancer later on, according to new research. Scientists discovered that serious viral infections can alter immune cells in the lungs, leaving behind chronic inflammation that may help tumors develop months or years later. The incr...

03/18/2026

Moffitt Cancer Center researchers have identified a more powerful predictor of immunotherapy response in non-small cell lung cancer than PD-L1 status alone.

Study shows tumor microenvironment ecology predicts response better than PD-L1 status alone

03/04/2026

Median Technologies' Eyonis LCS has received FDA 510(k) clearance as the first AI-based device for both detecting and diagnosing lung cancer in low-dose CT scans.

This device detects and characterizes lesions on low-dose CT scans, helping patients with cancer get faster, tailored care and avoid unnecessary procedures.

03/03/2026

Congratulations to Misty Shields and colleagues at the Indiana University School of Medicine and Moffitt Cancer Center!

Abstract. Small cell lung cancer (SCLC) is a recalcitrant thoracic malignancy known for acquired chemoresistance, early metastatic spread, and poor overall survival. Lurbinectedin, a DNA minor groove alkylating agent, provides durable efficacy in a minority. Predictive biomarkers for lurbinectedin a...

03/02/2026

Must-read insights from our good friend Dr. Jorge Nieva from USC Norris Comprehensive Cancer Center!

In this interview, a guest expert discusses how clinical pathways in EGFR- and ALK-mutated non-small cell lung cancer (NSCLC) must adapt to growing molecular complexity, integrate emerging technologies such as artificial intelligence and liquid biopsy, proactively manage toxicity, and balance innova...

03/01/2026

A comprehensive national study led by Harvard T.H. Chan School of Public Health found that U.S. counties located closer to operational nuclear power plants experience higher cancer mortality rates than those farther away.

U.S. counties located closer to operational nuclear power plants have higher rates of cancer mortality than those located farther away, according to a new Harvard Chan School study.

02/28/2026

Congrats to ALCMI consortium member NYU Langone Health! Researchers there have discovered that lipocalin 2 (LCN2), a protein produced by stressed cancer cells, enables lung and pancreatic tumors to evade immune attack by manipulating immune cells in the tumor microenvironment.

/PRNewswire/ -- A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows. Led by researchers from...

02/27/2026

Microplastics may be emerging as a serious danger to lung health.

Microplastics in the air are infiltrating human lungs, triggering oxidative stress, inflammation and cellular damage that may contribute to a range of serious respiratory diseases, a comprehensive new scientific review has warned. The paper, published in Food Bioscience, synthesises evidence from do...

02/26/2026

Whoa! Mayo Clinic researchers led by Henrique Borges da Silva, Ph.D., have uncovered how lung tumors exploit regulatory T cells via P2RX7 to evade immunotherapy.

Mayo Clinic researchers identify how P2RX7-driven regulatory T cells promote immunotherapy resistance in lung cancer, pointing to a potential new treatment strategy.

02/25/2026

Pranshu Mohindra, MD, MMM, from University Hospitals Cleveland Medical Center Inc., presents a compelling case for expanding the use of hypofractionated radiotherapy in lung cancer treatment.

Pranshu Mohindra, MD, outlined considerations for optimizing the use of hypofractionated radiation for patients with lung cancer.

Address

1100 Industrial Road, Suite 1
San Carlos, CA
94070

Telephone

+16505982857

Website

https://alcmi.org/

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