12/27/2025
In clinical practice, I see a specific pattern emerging in high-performing women aged 45–55.
They have the discipline. They have the "get it done" mindset. But suddenly, their bodies stop responding to the math of "calories in vs. calories out."
This is Neurometabolic Dysregulation. When you layer the hormonal shifts of perimenopause on top of an ADHD brain, the result is a system-wide communication breakdown. Conventional medicine often separates these into "psychiatry" or "endocrinology," but your body sees them as one integrated system.
If you can’t out-discipline your fatigue or out-work your brain fog, it's time for a different framework.
Drop a “ME” in the comments if you’re ready for the clinical answers to why your body feels like it’s working against you.