Engage Chiropractic

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Engage Chiropractic Kate Transier DC
Chiropractic care for people, and large and small animals. Topeka, KS and surrounding areas. Manual adjustments. Dry needling. Private pay.

FAKTR myofascial therapy.

24/04/2026
15/04/2026

The White Foam on Her Coat Isn't a Disease. It's a Biological Masterpiece.
A wild Mustang gallops across the dusty, warm taupe plains, her chest and flanks covered in thick, soapy white lather.

We see this heavy foam after exertion and assume she is desperately sick or suffering from a severe skin infection.

In reality, this free-roaming Mustang (Equus caballus, Status: Managed) is utilizing the most sophisticated cooling system of any land mammal. Right now in March, as she sheds her dense winter coat while navigating unseasonably warm spring days, she risks severe hyperthermia. To survive, she produces latherin—a unique surfactant protein found only in equids. Without it, sweat would uselessly bead on top of her thick fur. Latherin drastically cuts surface tension, allowing water to pe*****te straight through the coat to the skin for instant evaporative cooling.

As she travels miles across the arid landscape, she acts as a keystone grazer, trampling seeds into the earth to regenerate native dryland grasses. Her extreme stamina, fueled by latherin, makes this ecological role possible.

If you observe wild horses running this spring, never pursue them in vehicles, which forces dangerous, unnatural overheating.

She isn't sick. The thick foam is just proof her magnificent body is working perfectly to keep her alive.

14/04/2026
10/04/2026

Most people who take CoQ10 think of it as an antioxidant. It is one. But that is not the most important thing it does.

CoQ10 is the only mobile electron carrier in the inner mitochondrial membrane. The electron transport chain has four protein complexes fixed in the membrane. Complex I accepts electrons from NADH. Complex II accepts them from FADH2. But neither can pass those electrons directly to Complex III. They hand them to CoQ10, which physically shuttles across the lipid bilayer to deliver them. Complex III passes them to Complex IV, which reduces oxygen to water and drives the proton gradient that ATP synthase uses to produce ATP.

Without CoQ10, the chain breaks between Complex I/II and Complex III. Electrons have nowhere to go. The proton gradient collapses. ATP production stalls. This is not an antioxidant function. This is the core mechanism of aerobic energy production.

CoQ10 is predominantly synthesized endogenously through the mevalonate pathway, the same pathway that produces cholesterol. HMG-CoA reductase is the rate-limiting enzyme. Statins inhibit HMG-CoA reductase. That is how they lower cholesterol. It is also how they lower CoQ10.

An updated meta-analysis by Qu et al. (2018) pooled 12 RCTs with 1,776 participants and found statins significantly reduced circulating CoQ10. The reduction was independent of statin type, intensity, or treatment duration. Both lipophilic and hydrophilic statins produced the same effect. This is consistent with what the biochemistry predicts: the pathway is shared.

On top of statin-induced depletion, CoQ10 in human heart tissue declines naturally with age. Kalén et al. (1989) measured CoQ10 concentrations in myocardial tissue and found levels peak around age 20, decline by more than 30% by age 40, and drop approximately 50% by age 80. The organ with the highest energy demand loses half its electron carrier over a lifetime.

A 2025 meta-analysis by Kovacic et al. (Journal of Nutritional Science, 7 RCTs, 389 patients) found CoQ10 supplementation significantly reduced statin-associated muscle symptoms measured by pain intensity. This is the most current pooled data on clinical outcomes.

One important nuance: while plasma CoQ10 depletion from statins is well established, whether intramuscular CoQ10 drops proportionally is inconsistent. Some studies found no change or even increases in muscle tissue CoQ10 during statin treatment. The plasma reduction may partly reflect reduced LDL particles, which are the primary carriers of CoQ10 in blood. The clinical significance of depletion beyond muscle symptoms remains debated.

Roughly 200 million people worldwide take statins. The mevalonate pathway that produces their target also produces the electron carrier their mitochondria depend on. The mechanism is not controversial. The clinical implications are still being defined.

Kalén et al., Lipids, 1989.

Qu et al., Eur J Med Res, 2018.

Kovacic et al., J Nutr Sci, 2025.

01/04/2026

Day 090 of 365

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Tuesday 12:00 - 19:00
Wednesday 09:00 - 17:30
Thursday 09:00 - 16:30
Friday 07:30 - 13:00

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(816) 718-9660

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Why Engage?

The foundation-

The practice of chiropractic is based upon the foundational principle that the body has the capability to heal from within, and when necessary adapt to changes in its environment. This is what we call innate. Scientifically we know the nervous system is the master system of the body which controls and coordinates all other organ systems of the body, and relates the body to the environment. The nervous system is made up of the brain and spinal cord which is protected by the vertebrae that make up the spine of the animal. The spine, is designed to allow movement of the animal’s body, but if normal motion of the vertebra of the spine is restricted or decreased (this is what we call a subluxation), it can cause inhibition of the spinal nerves that exit between the vertebra and interfere with the nervous systems ability to function properly. A chiropractic adjustment restores proper motion of the joints of the spine, reduces the interference of the nervous system, and engages the body’s innate. Engage the body, engage the potential.

The application-