Advanced Prenatal Therapeutics

Advanced Prenatal Therapeutics Advanced Prenatal Therapeutics (APT) is developing a novel therapeutic device for treating preeclampsia - targeted apheresis. It is a completely unmet need.

Preeclampsia is a condition that occurs in approximately 5-8% of pregnant mothers in the US, and 14% worldwide. It is characterized by high blood pressure and protein in the urine arising after the 20th week of gestation. There are currently no pharmaceuticals or medical devices approved for treatment of preeclampsia. Current treatment includes bed-rest, close monitoring of the mother's condition

with supportive measures, and prayer. The only cure for preeclampsia is to delivery the baby, often prematurely. Preeclampsia is the leading cause of preterm births, maternal death (approx. 76,000 annually), and accounts for over 10,000 infant deaths in the US and approximately 500,000 infant deaths worldwide each year. Advanced Prenatal Therapeutics targeted therapy for preeclampsia is a simple procedure in which disease-causing factors in the mother's blood are specifically removed with APT's Targeted Apheresis Column for Preeclampsia (TAC-PE), while the blood components that are natural and vital are preserved. APT's mission is to develop an effective treatment that will safely prolong pregnancy, allowing babies more time to develop in the womb. Treatment with the TAC-PE will potentially extend the duration of pregnancy, thereby reducing the risk of lifelong disabilities in babies resulting from prematurity and IUGR. Apheresis is a common and safe procedure used therapeutically to treat several chronic diseases, even during pregnancy. Apheresis is a process similar to kidney dialysis in which whole blood is removed from a patient, filtered for a particular substance, and then returned to the patient. Our patent pending technology selectively targets the removal of blood components associated with the symptoms of preeclampsia. Specifically, the TAC-PE removes the harmful sFlt-1 receptors, thereby freeing circulating growth factors to bind to their target receptors in the mother. The TAC-PE is an affinity column that can be integrated into existing therapeutic apheresis devices. It consists of a rigid cylinder filled with immobilized agarose beads conjugated to proprietary sFlt-1 antibodies. To treat the patient, the woman's blood is pumped through an apheresis machine (1), which separates her blood into plasma and blood cells (2). The plasma is then circulated through the TAC-PE device (3), where the harmful sFlt-1 proteins are captured. The cleaned plasma is then remixed with the blood cells (4) and returned to the patient (5).

07/20/2022

Paula Eiselt and Tonya Lewis Lee’s documentary delves into the crisis of Black maternal mortality in the United States.

11/22/2021
totally
02/26/2020

totally

Some of the most important people in our lives are strong mothers, and even though most people don’t realize this, they are really quite abundant in this world. Though strong mothers are frequently found in this world, for some reason or another, they are not given the proper recognition that they...

02/10/2020
Kikkan kicks cancer's #@$%
12/10/2019

Kikkan kicks cancer's #@$%

Music video featuring Kikkan Randall, world-champion cross country skier, and other cancer survivors, family members, volunteers and caregivers telling cance...

10/17/2019

Keep Babies with Moms Suffering from Postpartum Depression

09/30/2019

Allyson Felix was part of the U.S. mixed-gender 4x400m relay team at worlds.

07/15/2019

Studies show that perinatal mood and anxiety disorders affect as many as one in five women.

06/12/2019

🗣LISTEN TO MOMS!
with
・・・
found that 1 in 6 of all women experience mistreatment by the health care system. this is a crisis. LISTEN TO MOMS.

06/03/2019

Sara gave birth to beautiful, healthy twins (Charlotte and Ryan) on 05/29/19. Sadly, Sara passed away several hours later due to complications following her pregnancy. As a now single parent of two, Dustin will need all the support he can get from friends and family to help him get ahead emotiona...

05/23/2019

On World Preeclampsia Day, our hearts go out to all the mothers, babies, and families affected by this devastating disorder. We pledge to continue our mission to bring to market novel, life-saving therapies that bring hope to future families and mothers, and hopefully will help bring an end to maternal and fetal loss of life. Preeclampsia Foundation

Send a message to learn more

05/13/2019

Lindsay Crosby passed away on July 4, just 10 days after giving birth to her third child

05/12/2019

"An American mom today is 50 percent more likely to die in childbirth than her own mother was," a Harvard Medical School obstetrician said

05/10/2019
Finally.
05/10/2019

Finally.

MTV is launching a campaign aimed at stemming the rise of maternal mortality in the U.S. Thursday’s launch of “Save Our Moms” comes as Mother’s Day approaches and will feature original content and educational resources across all MTV platforms

05/09/2019

It’s imprecise and can make families whose births are deemed not “natural” feel shame.

Address

Laguna Hills, CA

Telephone

+19493407261

Website

Alerts

Be the first to know and let us send you an email when Advanced Prenatal Therapeutics posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Practice

Send a message to Advanced Prenatal Therapeutics:

Shortcuts

Share