01/11/2023
In the literature, neuroinflammation has been linked with increased depression, schizophrenia, stroke, Parkinson’s Disease, multiple sclerosis, and sleep disorders to name a few conditions. Allergic reactions may cause a cascade of events that leads to swelling that increases the risk of depression. Stress may increase cytokines (CRP) a type of protein made by immune cells that can be disastrous to the immune system and lead to psychiatric pathologies such as psychosis and depression. Inadequate sleep may also increase cytokines which may lead to mood disorders.
Changes in gut permeability may affect immune responses and lead to inflammatory conditions such as ulcerative colitis, Crohn’s disease, and celiac disease. Increased body mass index is associated with an inflammatory state such as increased cytokines and fat cells located in the abdominal region. There is a correlation between neuroinflammation and early dementia.
As far as oral hygiene is concern, bacteria in the mouth may increase inflammation in the entire body especially the heart. An unhealthy diet Western diet can increase the body’s level of inflammatory markers while a Mediterranean diet (nuts, fish, and legumes) may decrease inflammatory responses in an individual’s body.
As it relates to Inactivity, there is an inverse relationship between exercise and inflammation. As an individual exercises, the rate of inflammatory markers decreases which is associated with less depression. Smoking increases inflammatory markers and may also lead to an increased risk of depression. Vitamin D has anti-inflammatory properties that may decrease oxidative stress, and reduce inflammation. Taking Vitamin D may decrease the risks of auto-immune disorders, such as multiple sclerosis.
