Nitric Oxide 2025

08/07/2025

Nitric Oxide Side Effects

GASTROINTESTINAL ISSUES, LIKE vomiting and diarrhea, are the most common side effects of nitric oxide supplements, Rothstein says.

Taking too much nitric oxide could potentially lead to “a massive vasodilation,” causing a drop in blood pressure and possibly leading to a stroke, Dr. Workman says.

Dizziness and headaches might happen too, Anzures says. “More serious side effects are allergic reaction and difficulty breathing.

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08/07/2025

08/07/2025

It Might Help With Respiratory Illnesses

A STUDY FROM a team of Chinese and American researchers found that inhaled nitric oxide could potentially be a treatment for critically ill Covid-19 patients. It’s thought that nitric oxide’s vasodilation properties may serve as effective therapy not just for Covid but for other respiratory and cardiovascular conditions related to the virus.

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Are Nitric Oxide Supplements Safe?

EXPERTS ARE mixed on whether you should take them, because there's not clear evidence that they work. But Dr. Workman says taking them is generally harmless for most people, you don't go overboard (see side effects and information on who shouldn't take them, below): “If people feel like they're struggling to get their exercise level to where they want it and feel like they're not able to recover, it's worth trying,” he says.

There’s no typically recommended dose of nitric oxide supplements. However, Rothstein says, “Doses between 6 to 13 grams are usually used in research studying L-arginine, and this appears to be tolerated well by most people.”

Anzures urges anyone considering taking nitric oxide supplements to talk to their doctor first, especially if you have high blood pressure, heart problems, or any other health condition or take medications.

Experts say your body makes enough nitric oxide naturally, so supplements generally aren’t necessary. And, according to a statement from the United States Anti-Doping Agency, supplements aiming to improve nitric oxide may contain large amounts of other ingredients like caffeine.

Keep in mind, too, that supplements are not regulated by the U.S. Food and Drug Administration like prescription and over-the-counter medications, Anzures adds.

08/07/2025

08/07/2025

It Could Help Lower Your Risk for Heart Disease

ALONG WITH HELPING improve blood pressure, nitric oxide might reduce your risk for heart disease, especially for people who don’t exercise regularly, Rothstein says.

“For these individuals, an increase in L-arginine may promote vasodilation that would not otherwise occur without the onset of exercise,” he adds. “If an individual for some reason was also not ingesting enough arginine in their diet, supplementation would help offset the lack of this nutrient.”

Supplements might also reduce the cardiovascular effects of type 2 diabetes. Nitric oxide production is also hindered in people with type 2 diabetes, and this diminishes the health of blood vessels, which increases the risk of heart disease and high blood pressure.

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08/07/2025

NITRIC OXIDE SUPPLEMENT

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OFTEN, NITRIC OXIDE supplements don’t actually contain nitric oxide; they just contain its precursors: L-arginine and sometimes L-citrulline. "Supplementation of these compounds provides the body with the building blocks for nitric oxide production,” Anzures says. L-arginine also helps the body build protein, according to the Mayo Clinic.

“The research linking the consumption of the precursor molecules to increase nitric oxide and subsequently improve markers of heart health, exercise performance, and treating erectile dysfunction (to name a few) is mixed and not strongly supported by the literature,” says Anzures.

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08/07/2025

NITRIC OXIDE SUPPLEMENT

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OFTEN, NITRIC OXIDE supplements don’t actually contain nitric oxide; they just contain its precursors: L-arginine and sometimes L-citrulline. "Supplementation of these compounds provides the body with the building blocks for nitric oxide production,” Anzures says. L-arginine also helps the body build protein, according to the Mayo Clinic.

“The research linking the consumption of the precursor molecules to increase nitric oxide and subsequently improve markers of heart health, exercise performance, and treating erectile dysfunction (to name a few) is mixed and not strongly supported by the literature,” says Anzures.

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READ TO KNOW MORE ABOUT NITRIC OXIDE SUPPLEMENT AND CLICK THE LINK TO ORDER NOW>>>>
https://rebrand.ly/NitricOxideSupplement-orderpage

OFTEN, NITRIC OXIDE supplements don’t actually contain nitric oxide; they just contain its precursors: L-arginine and sometimes L-citrulline. "Supplementation of these compounds provides the body with the building blocks for nitric oxide production,” Anzures says. L-arginine also helps the body build protein, according to the Mayo Clinic.

“The research linking the consumption of the precursor molecules to increase nitric oxide and subsequently improve markers of heart health, exercise performance, and treating erectile dysfunction (to name a few) is mixed and not strongly supported by the literature,” says Anzures.

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06/19/2025

Can You Get Nitric Oxide in Food?

YES. AND DR. WORKMAN says food sources of nitric oxide are always preferred to supplements. “They’re going to have that plus an almost unlimited number of beneficial ingredients in the form of antioxidants and vitamins,” he adds.
woman's hands chopping beetroot for squeezing juice
The precursor compounds of L-arginine and L-citrulline can be found in foods that are high in protein (both compounds are amino acids), including beans, legumes, red meat, dairy products, fish, and nuts, and seeds, Anzures says. “A proper diet should provide enough support for the proper creation of nitric oxide by the body for healthy individuals.”

Vegetables, especially beets and leafy greens, like spinach and arugula, are rich in nitrates, which are associated with higher nitric oxide levels in the body, says Natalie Rizzo, M.S., R.D., a New York City-based registered dietitian.

“One study found cyclists who drank beetroot juice two to three hours before exercise increased peak power and pedaling velocity,” Rizzo says. “Another review also shows that beetroot juice can increase overall endurance and power for athletes.” (Beetroot comes in supplement form, too. Find out more about that, here.)

Beets are also linked to increased strength and endurance performance as well as improvements in cognition during exercise, lower inflammation levels, greater antioxidant function, improved cognition, and more.

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06/19/2025

Who Shouldn’t Take Nitric Oxide?

ACCORDING TO A recent study, people with conditions including liver cirrhosis, guanidinoacetate methyltransferase deficiency and low blood pressure should be wary when it comes to nitric oxide.

The risk of the supplement’s side effects could be higher if you have any of these medical issues. You should also be very careful about taking nitric oxide if you have kidney disease, herpes, or heart conditions. People who’ve had heart attacks and subsequently take nitric oxide are not only at risk for repeated heart attack, but GI problems as well.

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