03/07/2020
Factual Friday Folks! Please share my posts, there may be someone you know that can use a CBD boost. More explained below.
So how does taking CBD work for you?
CBD ( which contains Cannabinoids) activates your bodies network of receptors (CB1 & CB2) or sensors , the Endocannabinoid system (ECS) , this system regulates your body’s environment, maintaining it’s homeostasis.
The receptors communicate internally from the brain to the nervous system about pain, for example as well as other stimuli.
So using CBD heightens the function of these receptors, enhancing the natural level of Cannabinoids.
Taking CBD you simply mimic what your body already creates, you are just providing it with some extra “oomph." 😄 And we all need that.......especially on a Monday morning!
You are all aware, that I cannot offer any medical advice, I am researching the evidence that exists and trying to use objective and recognised sources. So if you wish to look at CBD closer, to follow, a few exerts from Wikapedia: (Have a fantastic week end!)
"The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors (CBRs), and cannabinoid receptor proteins that are expressed throughout the vertebrate central nervous system (including the brain) and peripheral nervous system
Two primary cannabinoid receptors have been identified: CB1, first cloned in 1990; and CB2, cloned in 1993. CB1 receptors are found predominantly in the brain and nervous system, as well as in peripheral organs and tissues.
The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators[12][13][14] for a variety of processes, including motor learning,[15] appetite,[16] and pain sensation,[17] among other cognitive and physical processes.
Energy balance and metabolism
The endocannabinoid system has been shown to have a homeostatic role by controlling several metabolic functions, such as energy storage and nutrient transport. It acts on peripheral tissues such as adipocytes, hepatocytes, the gastrointestinal tract, the skeletal muscles and the endocrine pancreas. It has also been implied in modulating insulin sensitivity. Through all of this, the endocannabinoid system may play a role in clinical conditions, such as obesity, diabetes, and atherosclerosis, which may also give it a cardiovascular role
Immune system
In laboratory experiments, activation of cannabinoid receptors had an effect on the activation of GTPases in macrophages, neutrophils, and bone marrow cells. These receptors have also been implicated in the migration of B cells into the marginal zone and the regulation
Analgesia – Pain Relief
The endocannabinoid most researched in pain is palmitoylethanolamide. Palmitoylethanolamide is a fatty amine related to anandamide, but saturated and although initially it was thought that palmitoylethanolamide would bind to the CB1 and the CB2 receptor, later it was found that the most important receptors are the PPAR-alpha receptor, the TRPV receptor and the GPR55 receptor. Palmitoylethanolamide has been evaluated for its analgesic actions in a great variety of pain indications[63] and found to be safe and effective.
Autonomic nervous system
Peripheral expression of cannabinoid receptors led researchers to investigate the role of cannabinoids in the autonomic nervous system. Research found that the CB1 receptor is expressed presynaptically by motor neurons that innervate visceral organs. Cannabinoid-mediated inhibition of electric potentials results in a reduction in noradrenaline release from sympathetic nervous system nerves. Other studies have found similar effects in endocannabinoid regulation of intestinal motility, including the innervation of smooth muscles associated with the digestive, urinary, and reproductive systems.[23]
Sleep
Increased endocannabinoid signaling within the central nervous system promotes sleep-inducing effects
