01/04/2024
Increasing your glutathione may provide health benefits, including reducing the oxidative stress that can contribute to symptoms in many different chronic conditions, including autoimmune disease. Glutathione is an antioxidant produced in cells. It’s comprised largely of three amino acids: glutamine, glycine, and cysteine. Glutathione levels in the body may be reduced by a number of factors, including poor nutrition, environmental toxins, and stress. Its levels also decline with age.
The Benefits of Glutathione
1. Reduces oxidative stress: Oxidative stress occurs when there’s an imbalance between the production of free radicals and the body’s ability to fight them off. Too-high levels of oxidative stress may be a precursor to multiple diseases. These include diabetes, cancer, and rheumatoid arthritis. Glutathione helps stave off the impact of oxidative stress, which may, in turn, reduce disease. An article cited in Journal of Cancer Science and Therapy indicated that glutathione deficiency leads to increased levels of oxidative stress, which might lead to cancer. It also stated that elevated glutathione levels raised antioxidant levels and resistance to oxidative stress in cancer cells.
2. May improve psoriasis
3. Reduces cell damage in alcoholic and nonalcoholic fatty liver disease
Cell death in the liver may be exacerbated by a deficiency in antioxidants, including glutathione. This can lead to fatty liver disease in both those who misuse alcohol and those who don’t. Glutathione has been shown to improve protein, enzyme, and bilirubin levels in the blood of individuals with alcoholic and nonalcoholic chronic fatty liver disease.
4. Improves insulin resistance in older individuals
As people age, they produce less glutathione. Researchers at Baylor School of Medicine used a combination of animal and human studies to explore the role of glutathione in weight management and insulin resistance in older individuals. Study findings indicated that low glutathione levels were associated with less fat burning and higher rates of fat storing in the body.
5. Increases mobility for people with peripheral artery disease
Peripheral artery disease occurs when the peripheral arteries become clogged by plaque. It most commonly Trusted Source happens in the legs. One study reported that glutathione improved circulation, increasing the ability of study participants to walk pain-free for longer distances.
6. Reduces symptoms of Parkinson’s disease
Parkinson’s disease affects the central nervous system and is defined by symptoms such as tremors. It currently has no cure. One older study documented intravenous glutathione’s positive effects on symptoms such as tremors and rigidity. While more research is needed, this case report suggests that glutathione may help reduce symptoms, improving quality of life in people with this disease.
7. May help fight against autoimmune disease
The chronic inflammation caused by autoimmune diseases can increase oxidative stress. These diseases include rheumatoid arthritis, celiac disease, and lupus. According to one study Trusted Source, glutathione helps reduce oxidative stress by either stimulating or reducing the body’s immunological response. Autoimmune diseases attack the mitochondria in specific cells. Glutathione works to protect cell mitochondria by eliminating free radicals.
8. May reduce oxidative damage in children with autism
Several studies Trusted Source, including a clinical trial reported in Medical Science Monitor Trusted Source, indicate that children with autism have higher levels of oxidative damage and lower levels of glutathione in their brain.
9. May reduce the impact of uncontrolled diabetes
Long-term high blood sugar is associated with reduced amounts of glutathione. This can lead to oxidative stress and tissue damage.
10. May reduce respiratory disease symptoms
Glutathione is found in some foods, although cooking and pasteurization diminish its levels significantly. Its highest concentrations are in raw or very rare meat, unpasteurized milk and other unpasteurized dairy products, freshly picked fruits and vegetables, such as avocado, and asparagus. Glutathione contains sulfur molecules, which may be why foods high in sulfur help to boost its natural production in the body. These foods include cruciferous vegetables, such as broccoli, cauliflower, Brussels sprouts, Bok choy, allium vegetables, such as garlic and onions, eggs, nuts, legumes, lean protein, such as fish, and chicken. Other foods and herbs that help to naturally boost glutathione levels include milk thistle, flaxseed, seaweed, and grass-fed whey.
Glutathione is also negatively affected by insomnia. Getting enough rest on a regular basis can help increase levels.
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