DR Reena Kumari-Medical Oncologist

28/03/2025

BREAKING 🚨: The U.S. Food and Drug Administration has expanded the indication for lutetium Lu 177 vipivotide tetraxetan to include adult patients with PSA-positive mCRPC who have been treated with ARPI therapy and are considered appropriate to delay taxane-based chemotherapy.

Read more here: https://hubs.li/Q03dXmlJ0

02/02/2025

New research shows that avoiding the preservatives parabens & phthalates for just 28 days reverses cancer-related changes in breast tissue.

The study was published in Chemosphere.

Researchers analyzed breast tissue samples before and after a 28 day period, revealing significant reversals of cancer-associated phenotypes. These changes included alterations in key cellular pathways such as PI3K-AKT/mTOR, autophagy, and apoptotic signaling, which are all linked to cancer development.

The study suggests that even short-term avoidance of these chemicals may have a measurable impact on breast tissue at the molecular level.

Parabens and phthalates are widely used as preservatives and fragrance enhancers in cosmetics and personal care products, but they also act as xenoestrogens — synthetic compounds that mimic estrogen in the body.

Since estrogen plays a role in breast cancer development, reducing exposure to these chemicals may help lower the risk of cancer-related cellular changes. This research underscores the importance of choosing products free from harmful endocrine disruptors and highlights a potential preventive strategy against breast cancer.

Learn more: https://pubmed.ncbi.nlm.nih.gov/36746253/ #:~:text=Breast%20Cancer%20Over%20Time%2C%20San%20Francisco%2C%20CA%2C,USA.%20*%20PMID:%2036746253.%20*%20DOI:%2010.1016/j.chemosphere.2023.138014.

13/07/2023

❕ Check out our new living guideline update, Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: https://fal.cn/3zNX8

01/03/2023

22/10/2022

Molecular subtypes of invasive , common associated gene mutations, incidence, metastatic patterns and relapse.

20/10/2022

The American Society of Clinical Oncology (ASCO) Guideline on Treatment of Metastatic Colorectal Cancer - https://fal.cn/3sOlo

08/09/2022

https://rb.gy/psudws

In a systematic review and meta-analysis of phase III trials of treatment in patients with advanced reported in JAMA Oncology, expression was the strongest predictor of overall survival benefit in patients with and the second-strongest predictor—after –high status—in those with .

29/06/2022

In the words of Dame Deborah James — please check your poo.

Deborah's amazing attitude was humbling and a lesson to us all. Her fundraising has helped countless cancer patients and her determination to raise awareness will have saved many lives.

The three main symptoms of bowel cancer are: blood in your poo, persistent change in your bowel habit, or persistent tummy pain or bloating.

If you're worried, please contact your GP. https://www.nhs.uk/conditions/bowel-cancer/

27/05/2022

Historically, invasive lobular carcinoma and ductal carcinoma breast cancers have been grouped together. But new research from our Dr. Jason Mouabbi highlights how these two subtypes differ and how treating lobular carcinoma differently will allow for more personalized treatment approaches. https://bit.ly/3t4ubKL