30/07/2023
Heatwave: How hot is too hot for the human body?
By James Gallagher
Europe has been baking in a heatwave nicknamed the settimana infernale - "week of hell" - in Italy. Temperatures above 50C have been recorded in China and the US, where body bags filled with ice are being used to cool hospital patients. The UK has just had its hottest ever June.
And in 2022, the UK recorded a temperature above 40C for the first time. Last year's heatwave has been blamed for 60,000 deaths across Europe.
It's no wonder the United Nations has warned we now live in the era of "global boiling".
"I think it's really important to realise it's no longer just something that's distant or far away from us or something in the future. We are really seeing it now," says Prof Lizzie Kendon from the Met Office.
So what does the changing climate mean for our bodies and our health?
I tend to collapse into a sweaty puddle when it gets hot, but I've been invited to take part in a heatwave experiment.
Prof Damian Bailey from the University of South Wales wants to give me a typical heatwave encounter. So we're going to start at 21C, crank up the thermostat to 35C and then finally up to 40.3C - equivalent to the UK's hottest day.
"You will be sweating and your body's physiology is going to change quite considerably," Prof Bailey warns me.
Prof Bailey leads me into his environmental chamber. It's a room-sized piece of scientific equipment that can precisely control the temperature, humidity and oxygen levels inside this airtight space.
I've been here once before to explore the effects of cold.
But the shiny steel walls, heavy door and tiny portholes take on new meaning in anticipation of the temperature being cranked up.
I feel like I'm staring out of my oven.
The temperature starts at a perfectly pleasant 21C when the first instruction to "completely strip everything off" comes from Prof Bailey.
In response to a raised eyebrow, I'm reassured we're going to work out how sweaty I get, by seeing how my weight changes.
Next, I'm connected to a dizzying array of gizmos tracking the temperature of my skin and my internal organs, my heart rate and blood pressure. A huge mouthpiece analyses the air I exhale and an ultrasound inspects the flow of blood to my brain through the carotid arteries in my neck.
"Blood pressure is working nicely, heart rate is working nicely, all of the physiological signals at the moment are telling me that you're in spiffing shape," Prof Bailey tells me.
We have one quick brain test to complete - memorising a list of 30 words - and then the fans kick in. The temperature is starting to rise.
My body has one simple goal - to keep the core temperature around my heart, lungs, liver and other organs at about 37C.
"The thermostat in the brain, or hypothalamus, is constantly tasting the temperature, then it sends out all of these signals to try to maintain that," says Prof Bailey.
We take a pause at 35C to take some more measurements. It's warm in here now. It's not uncomfortable - I'm just relaxing in a chair - but I wouldn't want to work or exercise in this.
Some changes in my body are already clear. I look redder. Damian does too, he's stuck in here with me. That's because the blood vessels near the surface of my skin are opening up to make it easier for my warm blood to lose heat into the air.
Also I'm sweating - not dripping, but positively glistening - and as the sweat evaporates, that cools me down.
We then plough on to 40.3C, and now I feel like the heat is pounding me.
"It's not linear, it's exponential. Five degrees centigrade [more] doesn't sound much, but it really is physiologically so much more of a challenge," Prof Bailey says.
I'm glad we're not going higher. When I wipe my hand across my brow it is sodden. It's time to repeat the tests.
When I chuck my sweaty clothes on the floor, towel off and climb back on the scales I'm shocked to learn I've lost more than a third of a litre's worth of water during the course of the experiment.
The cost of opening up all those blood vessels near my skin to lose heat is also clear. My heart rate has increased significantly and at 40C it is pumping an extra litre of blood per minute around my body than it was at 21C.
This extra strain on the heart is why there is an increase in deaths from heart attacks and strokes when temperatures soar.
And as the blood heads to my skin, it's my brain that loses out. Blood flow goes down and so does my short-term memory.
But my body's main goal - keeping my core temperature at around 37C - has been achieved.
"Your body is working really quite nicely to try to defend that core temperature, but of course, the numbers are suggesting you weren't the same beast at 40 degrees as you were at 21 and that's in less than an hour," says Prof Bailey.