
27/08/2025
Cancer: A Red Herring?
For decades, cancer has been explained as a genetic disease. Billions have been invested in sequencing mutations, developing targeted drugs, and chasing the “driver genes” of cancer.
But here’s the challenge:
Two people with the same cancer often show completely different mutations.
Even within a single tumor, mutations vary from cell to cell.
Many so-called “cancer mutations” appear in healthy tissues without causing disease.
So, are mutations really the root cause? Or are they a red herring distracting us from a deeper truth?
Dr. Thomas Seyfried, in his pioneering book Cancer as a Metabolic Disease, argues that cancer begins not in our genes, but in our mitochondria—the tiny powerhouses of our cells.
When mitochondria are damaged by inflammation, toxins, poor diet, or stress, cells lose their ability to produce energy efficiently. To survive, they shift to an ancient, less efficient pathway: fermentation of glucose and glutamine (the Warburg Effect). This metabolic reprogramming drives uncontrolled growth and instability, the hallmarks of cancer.
This perspective changes everything:
Genetic mutations are not the cause, but a consequence of dysfunctional metabolism.
Targeted genetic therapies will remain limited.
By contrast, metabolic therapies aim at the true root: cancer’s reliance on glucose and glutamine.
Emerging strategies include:
• Nutritional ketosis and intermittent fasting
• Caloric restriction to reduce glucose and insulin
• Modulating glutamine metabolism
• Hyperbaric oxygen to exploit cancer’s metabolic weakness
At the Metabolic Health Clinic, we believe prevention and therapy must focus on restoring mitochondrial health. Stable blood sugar, anti-inflammatory nutrition, circadian alignment, movement, and toxin avoidance are not “alternative”, they are foundational.
Over the next 5 years, integrity in medicine will depend not on follower counts, but on scientific clarity. If we continue chasing genetic shadows, we risk missing the deeper battle.
Cancer may well be a red herring. The real fight is for our metabolic health.
Dr. Tariq Naeem
Founder, Metabolic Health Clinic