The GUT CLUB

30/07/2025

Published today:

There is growing evidence for the relationship between the gut microbiota and the effect of chemotherapy. Therefore, this systematic review provides an overview of the current evidence on the effects of the gut microbiota on chemotherapy response, efficacy and toxicity in patients with cancer. PubMe...

30/07/2025

30/07/2025

Trying to quit, but making excuses?
Or, using ni****ne as therapy in context of Bacteroidetes dominance coupled with reduced butyrate and niacin producers?

Please join The Gut Club: Stool Test Discussion Group
p.s.- niacin (nicotinic acid) is oxidized ni****ne.

(2024) Estimating causality between smoking and abdominal obesity by Mendelian randomization. Addiction. doi.org/10.1111/add.16454

Article:
‘Smoking linked to increased abdominal fat’
https://www.news-medical.net/news/20240321/Smoking-linked-to-increased-abdominal-fat.aspx

'Effects of Smoking and Smoking Cessation on the Intestinal Microbiota' (2020)
https://doi.org/10.3390/jcm9092963
"After 12 weeks, relative abundances of the phylum Bacteroidetes increased (pANCOVA = 0.048) and Firmicutes decreased among abstainers compared to continuing smokers. Increases in alpha-diversity were associated with heart rates, systolic blood pressures, and C-reactive protein."

'Sodium butyrate (SB) ameliorated inflammation of COPD induced by cigarette smoke through activating the GPR43 to inhibit NF-κB/MAPKs signaling pathways' (2023)
https://www.sciencedirect.com/science/article/pii/S0161589023002055
"Our results showed that CSE down-regulated the mRNA levels of G-protein-coupled receptor 43 (GPR43) and GPR109A, while SB only up-regulated the expression of GPR43 and had no effect on GPR109A."

Control of MCAS via butyrate and niacin activating GPR109A:
https://www.facebook.com/photo/?fbid=1107318521451427&set=a.433819348801351

29/07/2025

2025:

As the adsorption receptor of bacteriophage tail protein, bacterial lipopolysaccharide (LPS) is a main culprit responsible for nonalcoholic fatty liver disease (NAFLD) caused by high-fat diets. However, few studies have focused on how the interaction between intestinal bacteriophages and bacterial L...

29/07/2025

https://journals.asm.org/doi/10.1128/msphere.00781-23

Rising antimicrobial resistance has made treatment of bacterial infections increasingly difficult. According to the World Health Organization, it has become a burgeoning threat to hospital and public health systems worldwide. This threat is largely ...

29/07/2025

Please join The Gut Club Stool Test Discussion Group:
https://www.facebook.com/groups/TheGutClubStoolTestDiscussionGroup/

The Gut Club is now producing Ketosana Advanced Kefir Grains™:
https://thegutclub.org/product/ketosana-advanced-kefir-grains/

Interview with Dr. Mindy Pelz-Hall:
https://www.facebook.com/thegutclub23/photos/a.1277925552233310/3074531092572738/?type=3&theater

29/07/2025

April 2020, still applies/
https://thegutclub.org/the-coronavirus-covid-19-gut-lung-axis-shortlist

The Coronavirus COVID-19 Gut-Lung Axis Shortlist This is about needing balanced microbes in our intestines in order to have a healthy immune response which doesn’t damage our lungs. That’s the gut-lung axis where our microbiota guide immune response to the new SARS-CoV-2 virus (severe acute resp...

29/07/2025

Intestinal Permeability Targeted Re**al E***a Nutraceutical Intervention in Dogs with Cutaneous Adverse Food Reactions: Gut-Brain-Skin Axis Directed Pro-active Treatment Abstract views: 219 / PDF downloads: 178 Authors Kerem Ural Hasan Erdogan Songul Erdogan Tuğba Aslan Cansu Balıkçı Gamze Gök....

29/07/2025

Tiger nuts:

How to Make Orxata de Xufa When it really gets hot in Barcelona, many reach for a cold glass of orxata. There are many orxaterias in town, or you can try your hand at making your own! Orxata: What and How Orxata de xufa (or horchata de chufa in Castilian) is a common sight in the summer months, with...