24/12/2025
🚨 A new peer-reviewed analysis in Molecular Oncology highlights the potential of routine daily vitamin D supplementation for adults aged 50+ to prevent approximately 30,000 cancer deaths annually in Germany alone.
This is driven by a consistent ~13% reduction in cancer mortality, as demonstrated across multiple meta-analyses of randomized controlled trials (RCTs).
Key findings from the study:
• Lives saved: ~30,000 fewer cancer deaths per year in Germany
• Life-years gained: ~322,000 life-years saved annually
• Cost per person: ~€11–€55 (approx. $12–$60 USD) per year
• Total supplementation cost: ~€1.0 billion annually
• Net healthcare savings: ~€280 million ($300 million USD) per year, due to reduced end-of-life cancer care expenses
• Cost per life-year saved (conservative estimate, ignoring care savings): ~€3,100—far below thresholds for new cancer drugs
This intervention is supported by over 900 recent studies detailing vitamin D's anti-cancer mechanisms, including:
• Suppression of tumor growth, proliferation, metastasis, and epithelial-to-mesenchymal transition (EMT)
• Induction of cell death (apoptosis and ferroptosis)
• Immune modulation and improved tumor microenvironment control
• Enhanced response to chemotherapy and immunotherapy, with reduced treatment resistance
Benefits observed across multiple cancers, such as breast (including triple-negative), prostate, colorectal, ovarian, lung, melanoma, bladder, and more.
Low vitamin D levels are linked to worse prognosis and more aggressive disease, while adequate levels correlate with better survival.
In contrast to modern oncology drugs—which often cost tens of thousands per patient for marginal survival gains of weeks or months—vitamin D offers a low-cost, evidence-based option that could shift focus toward effective prevention and lower overall healthcare spending.
As the analysis notes: "The only real question left is why public health policy continues to ignore it."
Especially relevant during winter months when vitamin D levels typically decline—consider discussing testing and supplementation with your healthcare provider.
🔗 https://febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12924
🔗 https://www.sciencedirect.com/science/article/pii/S0960076023000638
🔗 Full article: https://www.thefocalpoints.com/p/vitamin-d-could-prevent-30000-cancer