
02/07/2025
Scientists created a cream that can bring hair back — it cures baldness with just one week of use.
The age-old quest for a cure for baldness may be entering a promising new chapter, thanks to groundbreaking research from UCLA scientists.
After years of experimentation, the team has identified a molecule—dubbed PP405—that can successfully awaken dormant hair follicles. In early human trials, participants who applied the molecule topically at bedtime for just one week showed statistically significant results.
Unlike many existing treatments that produce only wispy hair, PP405 is believed to stimulate the growth of full, terminal strands.
The molecule works by inhibiting a protein that keeps follicle stem cells dormant, effectively reactivating the body’s natural hair-growing capabilities.
The breakthrough comes from a trio of UCLA researchers: William Lowry, Heather Christofk, and Michael Jung, who have co-founded a startup, Pelage Pharmaceuticals, to further develop and commercialize the treatment. With $16.4 million in backing from Google Ventures, the team is preparing for larger clinical trials and working toward FDA approval. While the treatment won’t work for everyone, it holds promise for the majority of individuals affected by hair loss, including those who lose hair due to aging, stress, genetics, or chemotherapy. As the researchers cautiously advance through regulatory hurdles, optimism is mounting that a reliable cure for baldness may finally be on the horizon.
learn more https://newsroom.ucla.edu/magazine/baldness-cure-pp405-molecule-breakthrough-treatment