Science Based Nrf2

10/03/2021

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31/12/2019

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29/11/2019

STOP THE PRESSES 🛑‼️
..NO. WAIT. KEEP THEM RUNNING AT FULL CAPACITY!!! 🔥🔥🔥🔥

From our CSO, Dr. Brian Dixon!!

"Our scientific colleague, Dr. Christina Beer, was working on a research project. She found FOUR additional scientific, peer-reviewed studies on our own Nrf2 Synergizer.

That brings the total number of scientific studies on this one product alone to 31. THIRTY ONE!!!

I've never seen anything like this in the industry. And it continues to get better and better!"

We are seriously SO BLESSED to have our hands on this!!!!😍

SCIENCE Matters, Period.
No wonder there are so many doctors & health professionals a part our company!! This is why I’m here! Science done independently - not funded by our company - on a finished product (and NOT resting on the research of single ingredients).

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23/11/2019

👉Have you ever wondered why there are billions of dollars going towards cancer “research” (and other diseases) but still have no answers other than to pump drugs into the body? 🤔 There is NO MONEY in cures. However, there is A LOT of profit in “sickcare.” Side effects lead to more sales.

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“Nutrigenomics is the future...not medications.
Nutrigenomics is a field that combines the study of nutrition and gene expression. Scientists working in this field investigate how nutrients and other bioactive components in food affect important metabolic and physiological processes by “turning on” or “turning off” certain genes.”

- Eddie Hendricks 🎩🙌💙




13/09/2019

It just keeps getting better, I absolutely love being apart of the biggest shift in medicine. Do your homework.

NRF2 IN THE NEWS: 🛡💉🦠

The National Cancer Institute Cancer Therapy Evaluation Program JUST approved the University of Texas MD Anderson Cancer Center to start clinical research of the Nrf2 pathway this month.👍

⚠️THE STUDY: "A Phase II Basket Trial of Glutaminase Inhibitor (BeGIN) CB-839 HCl in Patients with NF1 Aberrations, NF1 Mutant Malignant Peripheral Nerve Sheath Tumors (MPNST), KEAP1/NRF2 and LKB1 Aberrant Tumors"

🤔What does that mean? Well, a "malignant peripheral nerve sheath tumor" (MPNST) is a tumor that develops in the protective lining that covers nerves. The first symptom of MPNST is often a lump or mass that increases in size, sometimes causing pain or a tingling sensation. So in short, it's not a good thing!!! 😰

What does it mean for us? 🤔
The take home message is quite simple for all of us. Activate your Nrf2 Pathway daily!!!

Nrf2 is a potent modulator of antioxidant response and can rapidly target oxidative stressors. While Nrf2 responds to oxidative stress directly, certain key nutrients can improve this effect, the exact source of these nutrients varies widely but dark green and leafy vegetables or reddy vegetables can help and of course there are herbs when compounded in a "right" ratio have been proven to reduce Oxidative stress as much as 40% in just 30 days! If you truly care about your health and the health of your family, get educated then get activated!!!!❤️👍💪

07/06/2019

A good read about what oxidative stress is and why Nrf2 Activation is so vital to prevention and overall good health🤓👇💙.

*Our all-natural Nrf2 activator is clinically proven to reduce oxidative stress by an average of 40% in 30 days and by 70% in 120 days.

http://sciencebasednrf2.lifevantage.com/

https://www.theepochtimes.com/coping-with-the-oxygen-paradox_2941770.html

Our body relies on this highly reactive substance to fuel essential chemical reactions, but sometimes oxygen does more than we'd ever want it to.

28/04/2019

When Nrf2 goes viral, traditional direct antioxidants will all but turn obsolete (they already are, they just aren’t aware of it yet). Choosing traditional antioxidants over Nrf2 activation is like choosing to travel by horse carriage over a jet🤷‍♂️.

✈️>🐎

“Nrf2 may well be the greatest scientific breakthrough in the history of medicine”

- Washington State University

https://newswire.net/newsroom/pr/00109289-growing-number-of-research-studies-suggests-antioxidants-prevent-various-diseases.html

NutraHerbals Ashwagandha is further recommended by the researchers because this natural remedy works wonders in decreasing kidney injury caused by oxidative stress.

31/03/2019

Dr. David Perlmutter, MD is a well-known educator in the area of brain health. He has been called the leading integrative medicine neurologist in North America today. He has written books such as Grain Brain, Brain Maker, and Power Up Your Brain.

He talks about the decline of brain health stemming from:
1. inflammation -> 2. free radicals -> 3. brain cell death.

He states, based on research that was published in Therapeutic Advances in Chronic Disease, that the level of inflammation in the body is correlated to both the rate of degeneration of the brain, as well as the degree of cognitive impairment during aging.

There are many reasons to decrease inflammation in the body, and brain health is just one of them.

One important way to control inflammation in the body is to reduce sugar intake. High blood sugar is a common contributor in our modern day diets to inflammation. It’s not the only cause of inflammation, but it is a MAJOR one that is under our control.

Secondly, another potent and easy way to decrease inflammation is NRF2 activation. NRF2 increases the expression of anti-inflammatory genes and decreases expression of pro-inflammatory genes.

Overall result -> decreased inflammation.

Not only does NRF2 activation directly address inflammation, but it powerfully activates the production of anti-oxidants, (including the master anti-oxidant, glutathione), which can get to work on quenching an over-abundance of free radicals.

If Dr. Perlmutter is right that: Inflammation -> Free Radicals -> Brain Cell Death

And NRF2 activation decreases BOTH Inflammation AND free radicals…

I can tell you how grateful I am to have NRF2 activation in my toolkit for my own health, as well as that of my friends and family.

31/03/2019

FRIENDS; WE HAVE BIO-HACKED THE BRAIN through the newest research results of brain mapping a teenager before and after using our world-renowned Nrf2 activation program. What are you waiting for--come join a company that is light-years ahead in research and development.
Get back with whomever shared this technology and page info with you.

14/03/2019

🤓 NEW STUDY: "Nrf2 appears to be a potential target for preventing and treating type 1 diabetes." 🔥

The transcription factor Nrf2...plays a critical role in oxidative stress responses. While activation of Nrf2 signaling is known to exert anti-inflammatory effects, Nrf2 function in inflammation-mediated autoimmune disorders, such as type 1 diabetes,... READ THE WHOLE STUDY BY GOING TO THE LINK BELOW:

https://joe.bioscientifica.com/view/journals/joe/240/3/JOE-18-0355.xml

16/12/2018

A MESSAGE FROM ADMIN: To all members of this page: “Science Based Nrf2” is being transitioned into our sister group “Friends Who Like Science Based Activators.” If you would like to be a member of our new and improved page, simply click on the link I provided in the comment section. Thank you for your support here and we look forward to seeing you at the new site.

22/11/2018

***PSA***

Oxidative Stress is directly linked to nearly ALL non-infectious disease. If you would like to know if a specific disease or condition is a result of OS, go to the National Library of Published Medical Research @ pubmed.gov and type “oxidative stress” followed by your disease/condition.

07/08/2018

05/08/2018

Three years ago, Dr. Martin Pall, PhD and Dr. Stephen Levine, PhD from Washington State University had their research findings published in a journal called Acta Physiologica Sinica titled, "Nrf2, a master regulator of detoxification and also antioxidant, antiinflammatory and other cytoprotective mechanisms, is raised by health promoting factors"

In this peer-reviewed publication, Drs. Pall and Levine proclaimed:
💥"[W]e may be on the verge of a new literature on health effects of Nrf2 which may well become the most extraordinary therapeutic and most extraordinary preventive breakthrough in the history of medicine."

A BOLD and REVOLUTIONARY statement, but a TRUE one.
Would you like to know what else these scientists stated about Nrf2?

I am not making claims of cure, treatment, mitigation, or prevention. I am simply posting EXCERPTS from Drs. Paul and Levine's research :

💥Raising Nrf2 has been found to PREVENT and/or TREAT a large number of CHRONIC INFLAMMATORY diseases in animal models and/or humans.

💥Nrf2 has been shown more recently to have many cytoprotective effects that go far beyond antioxidant effects. These include activation of over two dozen genes involved in DETOXIFICATION of a wide variety of xenobiotic toxicants.

💥Nrf2 and the system that regulates Nrf2 LOWER INFLAMMATORY responses, IMPROVE MITOCHONDRIAL FUNCTION and STIMULATE AUTOPHAGY, a process by which both toxic protein aggregates and dysfunctional organelles can be degraded. Three of these effects, the LOWERING OXIDATIVE STRESS, INFLAMMATORY BIOCHEMISTRY and IMPROVING MITOCHONDRIAL FUNCTION should LOWER the PATHOPHYSIOLOGY involved in dozens of CHRONIC INFLAMMATORY DISEASES and so may be expected to be useful in the prevention or treatment of many common chronic diseases.

💥The important DETOXIFICATION roles of Nrf2 mean that raising Nrf2 activity is likely to be of particular importance to the HUNDREDS OF MILLIONS OF PEOPLE around the globe who are regularly exposed to toxic chemicals that cause diseases characterized by oxidative stress, inflammation and mitochondrial dysfunction, diseases which include most of the chronic diseases of 21st century life.

💥The components of Protandim were shown in cell culture to act synergistically in raising Nrf2 responses, probably due to the role of multiple signaling pathways in their actions in raising Nrf2.

💥The STUNNING apparent BREADTH of the EFFECTS of Nrf2 on diverse diseases produces a challenge for medicine. Medicine has historically focused mainly on the ways in which these various diseases differ from one another, as a way of understanding their differences. However it is possible that these DIVERSE CHRONIC INFLAMMATORY DISEASES ALL have a SIMILAR UNDERLYING MECHANISM and differ from one another primarily in their localization in the body, with the differences in localization being responsible for any differences in their etiologies.

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The scientists then list "diseases where raising Nrf2 is reported to be useful in prevention and/or treatment in animal models and/or humans".

Cardiovascular diseases including atherosclerosis, ischemic cardiovascular disease, vascular
endothelial dysfunction, and heart failure
Neurodegenerative diseases including Alzheimer’s, Parkinson’s, ALS, Huntington’s diseases
Cancer (prevention)
Chronic kidney diseases
Metabolic diseases: Type 2 diabetes; metabolic syndrome; obesity
Several types of toxic liver disease
Chronic lung diseases including emphysema, asthma, and pulmonary fibrosis
Sepsis
Autoimmune diseases
Inflammatory bowel disease
HIV/AIDS
Multiple sclerosis
Epilepsy
Hemoglobinopathies including sickle cell disease and β-thalassemia
Malaria
Spinal cord injury
Traumatic brain injury
Altitude sickness
The three classic Psychiatric diseases, major Depression, Schizophrenia and Bipolar disorder
Gastric ulcers
Glaucoma
Age-related macular degeneration
Cataract
Pathophysiological responses to herpes activation
Benign prostatic hyperplasia


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If this doesn't make you want to take that Little Yellow Pill every day for the rest of your life, I don't know what will!!!😁😁😁

05/07/2018

http://www.herald-dispatch.com/news/marshall_university/mu-research-team-defines-possible-anti-aging-intervention/article_be49cbf1-b641-5633-8e50-b5b12be8578d.html

The Herald-DispatchHUNTINGTON - New research from a team at the Marshall University Joan C. Edwards School of Medicine demonstrates the Na/K-ATPase oxidant amplification loop, known as NAKL, is intimately involved

01/07/2018

H/T Kate Thanh Ly!

💥Mayo Clinic Translational Study on Protandim Nrf2💥
A translation study aims to "translate" findings in fundamental research into medical practice and meaningful health outcomes.

Dr. Prasongsook, an MD (internal medicine) seeking his graduate research degree in Medical Oncology at the Mayo Clinic in Rochester, MN, was looking for nutraceutical approaches for the treatment of ovarian cancer.🤔

He studied our awesome Little Yellow Pill.

👀 See for yourself what Dr. Prasongsook found. You will be AMAZED 😮

29/06/2018

https://www.eurekalert.org/pub_releases/2018-06/ru-bfc062818.php

The National Institutes of Health has awarded a five-year grant for Rice University scientists to investigate a biochemical domino effect that may be involved in diseases and conditions ranging from Alzheimer's and cancer to Parkinson's and age-related muscle atrophy.

13/05/2018

https://pubs.acs.org/doi/abs/10.1021/acs.jpcb.8b03295?journalCode=jpcbfk

Prediction of Binding Energy of Keap1 Interaction Motifs in the Nrf2 Antioxidant Pathway and Design of Potential High Affinity Peptides

26/04/2018

New Study from the National Institute of Aging Interventions Testing Program (NIA ITP) Shows Protandim Significantly Extends Lifespan!

Let me repeat that, and let it sink in..our NRF2 activator is the only natural supplement PROVEN to extend lifespan, by improving health!!
Join the Biohacking Revolution today!

24/04/2018

https://www.eurekalert.org/pub_releases/2018-04/eb2-get041218.php

Increased awareness of the importance of the microbes that live in our gut has spurred a great deal of research on the microbiome and fueled a booming probiotics industry. A new study suggests probiotics can improve not only the health of our gut but liver health, as well.

24/04/2018

Yet, another study validating that oxidative stress is the culprit of Parkinson’s.
https://www.medicalnewstoday.com/articles/321572.php

The results of a decade-long study are in: a new therapeutic target is found, and scientists manage to slow the progression of the disease in animals.

22/04/2018

https://www.fasebj.org/doi/abs/10.1096/fasebj.26.1_supplement.1118.5

Pharmacology/Experimental TherapeuticsComparison of the Dietary Supplement Protandim and 4- Hydroxytamoxifen on Pre-malignant Human Breast Cancer Cells in 3D CultureAllison Dugan, Michelle Carroll-Turpin, Samuel Crooks, Songlin Zhang, Michael Mathis, and Heather E Kleiner-HancockAllison DuganPharmac...

21/04/2018

If you know anybody with fibromyalgia, NRF2 could help.
https://www.nrf2.com/fibromyalgia-oxidative-stress-and-nrf2-any-hope/

Before jumping into the impact of Nrf2 activation on Fibromyalgia and it potential benefits, let’s review a few common facts about the illness. What is Fibromyalgia? Fibromyalgia is a relatively common condition in which an individual experiences pain and discomfort throughout the body. Side effec...

17/04/2018

https://www.dovepress.com/ketamine-ameliorates-oxidative-stress-induced-apoptosis-in-experimenta-peer-reviewed-article-DDDT

Ketamine ameliorates oxidative stress-induced apoptosis in experimental traumatic brain injury via the Nrf2 pathway Jinwei Liang, Shanhu Wu, Wenxi Xie, Hefan He Department of Anesthesiology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People’s Republ...

16/04/2018

Our Nrf2 Activator reduces oxidative stress, the root cause of Rheumatoid Arthritis.

This is a conclusion from a clinical study on the role of oxidative stress in rheumatoid arthritis, published at PubMed.

CONCLUSION: These results provide strong evidence that oxidative stress is significantly involved in cartilage degradation in experimental arthritis, and indicate that the presence of a functional Nrf2 gene is a major requirement for limiting cartilage destruction.

You may read full details of the clinical study here:
http://www.ncbi.nlm.nih.gov/m/pubmed/21173018/

If you have questions, please contact
me.

Ann Rheum Dis. 2011 May;70(5):844-50. doi: 10.1136/ard.2010.132720. Epub 2010 Dec 20. Research Support, Non-U.S. Gov't

14/04/2018

Peer reviewed paper #17...ALS.

https://www.tandfonline.com/doi/full/10.3109/21678421.2015.1088707

(2016). ALSUntangled No. 31: Protandim. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration: Vol. 17, No. 1-2, pp. 154-156.

14/04/2018

If only there was a way to activate the body’s own antioxidant response, indirectly🤔.

https://mitochondrialdiseasenews.com/2018/04/13/antioxidants-show-promise-models-mitochondrial-disease-study/

The antioxidants vitamin E and N-acetylcysteine (NAC) prolonged survival and protected against brain damage in models of mitochondrial disease and will be tested in clinical trials.