BioViva Sciences Inc

01/03/2026

https://pulse.ly/8p6qo1zb0h

In this episode, Anders Indset speaks with Liz Parrish, CEO of BioViva, pioneering advocate for gene therapies, and likely the world's most gene-modified per...

01/03/2026

Dustin Vidrine, who is losing his vision from inherited retinitis pigmentosa, represents how life-changing gene therapies offer hope to preserve sight but remain difficult to access due to high costs, limited specialist availability, and insurance and geographic barriers.

Gene therapies have the potential to cure some diseases, but they are extraordinarily expensive. Location can also be a big hurdle for patients seeking this specialized care.

28/02/2026

Scientists have identified a conserved aging-related protein, EPS8, that promotes toxic protein aggregation linked to neurodegenerative diseases.

Scientists have identified a conserved aging-related protein, EPS8, that promotes toxic protein aggregation linked to neurodegenerative diseases.

27/02/2026

Gold represents transformation. And few embody that more than Liz Parrish. ✨

She didn’t just speak about changing the future—she stepped into it AGAIN. By undergoing two gene therapies never taken before and targeting the pathways against fatty liver disease, metabolic dysfunction, and the deeper mechanisms of aging itself. She took the risk - we applied for the patent to open it to the world.

A decision made not just for self, but for humanity. We wish her the best health and success.

The future doesn’t arrive on its own. Someone has to build it.

26/02/2026

I am pleased to announce that I will be speaking at the Unicorn Summit 2026 Europe Edition, in Lisbon, Portugal, on May 30, 31st, 2026. I look forward to joining Jeff Hoffman, Naveen Jain, Jack McCauley, and many other outstanding speakers, investors, and startup founders for this exceptional event. Will you be joining us?

26/02/2026

A hyaluronic acid hydrogel for sustained delivery of FGF21-enriched mesenchymal stem cell exosomes that promotes protective microglial polarization via STAT3/SOCS3 signaling, reduces neuroinflammation, and improves functional recovery after spinal cord injury.

Spinal cord injury (SCI) initiates a cascade of secondary pathological events largely driven by neuroinflammation, where microglial polarization plays a pivotal role. Modulating microglial polarizati...

25/02/2026

NIH-funded researchers identified specific transcription factors (such as EZH2, E2F3, STAT3, and ZFX) that can partially reverse age-related gene expression changes, improving cell function and liver health in aged mice, suggesting that targeting transcription factors may help slow or reverse aging-related diseases.

By altering levels of molecules called transcription factors in mice, researchers were able to reverse some of the effects of aging.

23/02/2026

The idea is that each cell in the body that receives the initial delivery will make lots of copies of the gene-editing machinery and pass most of them on to its neighbours, amplifying the effect.

The idea of self-amplifying gene editing is to get cells to pass on packages of CRISPR machinery to their neighbours, boosting the effect

22/02/2026

A large international study found that shorter telomere length—a marker of biological aging—is strongly linked to a higher risk and greater severity of age-related cataracts, suggesting that cataracts reflect systemic aging processes rather than just normal wear and tear of the eye.

Age-related cataract is often viewed as an unavoidable consequence of growing older, yet people of the same age frequently show striking differences in when cataracts appear and how severe they become.

21/02/2026

Laminopathies are rare genetic diseases caused by changes in a gene called LMNA, and we found that these changes can lead to shortened chromosome ends (telomeres) in heart cells, causing the heart muscle cells to enlarge and function abnormally—helping explain why these patients often show signs of early aging, especially in the heart. Find PDF in the Link

Laminopathies are a group of rare disease due to mutations in the LMNA gene, which is crucial for nuclear integrity and cellular rigidity. Depending on the mutation, the disease manifests in striated muscles, adipose tissues, nerves, and the heart. Although many laminopathic patients exhibit acceler...

20/02/2026

Within this group, the team identified two transcription factors, ZSCAN20 and JDP2, that had not previously been associated with T cell exhaustion. When these factors were turned off, exhausted T cells recovered their ability to destroy tumors while still retaining their potential to provide long-term immune memory.

Scientists uncover a new “recipe” that shows how exhausted T cells can be reprogrammed to regain their ability to attack tumors.