
16/09/2025
We all know that foggy-headed feeling that sets in after a poor night’s sleep, right?
Rather than reaching for coffee which can crash your nervous system, a study has shown that supplementing with creatine can temporarily improve cognitive performance and reduce fatigue during sleep deprivation.
STUDY METHOD
Participants were split into two groups. One group received a high dose of creatine (0.35 g per kg), while the other took a placebo during a 21-hour period of partial sleep deprivation.
Researchers monitored brain chemistry and tested participants’ cognitive function with standard assessments.
RESULT
They found that creatine supplementation helped sustain normal phosphocreatine and ATP levels in the brain, even when participants were severely sleep-deprived. Creatine users also performed better on tasks measuring working memory and processing speed than those who received the placebo.
The study used a relatively high dose of creatine, around 24.5 g of creatine, which aligns with discussions that the brain may require a higher dose than muscles.
🤍
It all makes sense. As creatine creates energy which your brain and muscles constantly rely on, poor sleep will deplete your body's natural supply.
A temporary high dose is shown to be beneficial in times of sleep deprivation but I recommend taking 3-5grams daily to build up and maintain your body's creatine stores and see how you feel.
I take and recommend Creatine Bioactive