
15/09/2025
Amniotic Membrane can be donated post-birth and prepared into tissue grafts for treating burns, wounds, ulcers, and some eye conditions.
WHAT IS AMNION?
The amniotic membrane is a thin-walled sac that surrounds the foetus inside the placenta. It holds the fluid within which the baby can develop and grow until birth.
WOUND HEALING PROPERTIES OF AMNIOTIC MEMBRANE:
Amnion is composed of a diverse collection of stem cells, growth factors, anti-inflammatory factors, and immunosuppressive cytokines, and has been used in wound care since 1910.
The amniotic membrane:
▪ is non-immunogenic (will not be seen as a ‘foreign’ material)
▪ enhances the wound healing process
▪ reduces scar tissue formation, inflammation, and pain when applied to a wound
▪ provides a matrix for the accumulation and proliferation of new cells
▪ provides a biological anti-bacterial barrier that protects injuries from infection
Ophthalmologists use amniotic membrane as a treatment for eye injuries and conditions, such as:
▪ persistent epithelial defects and non-healing corneal ulcers,
▪ corneal perforations and descemetoceles,
▪ bullous keratopathy,
▪ corneal disorders with associated limbal stem cell deficiency, and
▪ conjunctival reconstruction
AMNION DONATION
▪ Amnion is collected AFTER a live birth which has been delivered by an elective caesarean section.
▪ Neither the mother nor the foetus is harmed or affected in any way.
▪ It is a legal requirement for the mother to volunteer to donate her placental tissue.
▪ Donors do not need to pay towards any costs associated with donating.
For more information on amnion and/or to find out more about becoming a donor please speak to your medical doctor or email Bay Tissue Institute (BTI): admin@baytissue.co.za.
BTI is a Port Elizabeth based, non-profit organisation registered to harvest and supply amnion tissue (https://baytissue.co.za/).