10/02/2026
Pregnancy and Birth
Human development begins with fertilization in the ampulla of the fallopian tube, where a s***m fuses with the secondary oocyte to form a diploid Human development begins with fertilization in the ampulla of the fallopian tube, where a s***m fuses with the secondary oocyte to form a diploid.
The zygote undergoes cleavage into 2-cell, 4-cell, and 8-cell stages without increase in size, leading to morula formation. The morula enters the uterine cavity and converts into a blastocyst consisting of trophoblast and inner cell mass.
The blastocyst implants into the endometrium, establishing maternal support for embryonic growth.
The inner cell mass forms the embryo, while the trophoblast forms the chorion and contributes to placenta formation.
Chorionic villi develop to increase the surface area for maternal–fetal exchange. The placenta connects to the fetus through the umbilical cord containing two umbilical arteries and one umbilical vein. The fetus remains enclosed within the amniotic sac filled with amniotic fluid, providing protection, temperature regulation, and movement.
Maternal and fetal blood do not mix directly; exchange occurs through placental membranes. Fetal circulation includes ductus venosus, foramen ovale, and ductus arteriosus to bypass liver and lungs.
The first trimester establishes all major organ systems. The second trimester shows rapid growth and structural differentiation. The third trimester shows functional maturation and weight gain.
At term, the fetus lies in cephalic position within the uterine cavity above the cervix. Labor begins with rhythmic uterine contractions.
The first stage causes cervical effacement and dilation. The second stage results in expulsion of the fetus through the birth canal. The third stage results in expulsion of placenta and membranes. After birth, the umbilical cord is cut, fetal shunts close, pulmonary circulation starts, and independent respiration begins.
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