13/07/2025
𝐑𝐚𝐛𝐢𝐞𝐬: 𝐀 𝐃𝐞𝐚𝐝𝐥𝐲 𝐛𝐮𝐭 𝐏𝐫𝐞𝐯𝐞𝐧𝐭𝐚𝐛𝐥𝐞 𝐃𝐢𝐬𝐞𝐚𝐬𝐞
Rabies is a viral zoonotic disease that affects the central nervous system of mammals, including humans. It is caused by the Rabies virus, belonging to the genus Lyssavirus.
Transmission
Rabies is primarily transmitted through the bite of an infected animal. Dogs are the main source of human rabies deaths, contributing to about 99% of all transmissions. The virus can also enter the body through saliva contact with open wounds or mucous membranes.
Pathogenesis
After entering the body, the virus travels via peripheral nerves toward the brain. Once it reaches the central nervous system, it causes fatal encephalitis. Death is almost certain once clinical symptoms appear.
Clinical Signs in Animals
Rabies occurs in two forms:
Furious Rabies: Aggression, biting, excessive salivation, inability to swallow.
Paralytic Rabies: Weakness, incoordination, progressive paralysis, drooping jaw.
Symptoms in Humans
Initial signs include fever and tingling at the wound site, followed by confusion, agitation, hydrophobia (fear of water), hallucinations, and eventually coma and death.
Prevention
Vaccination of dogs and cats is the most effective way to prevent rabies.
Post-exposure prophylaxis (PEP) in humans is critical after any potential exposure.
Community-wide dog vaccination programs are essential for breaking the transmission cycle.
Veterinary Importance
Veterinarians play a crucial role in:
Preventing rabies at its animal source.
Promoting public education on responsible pet ownership and bite prevention.
Leading vaccination campaigns and reporting suspected cases.
Global Concern
Rabies causes around 59,000 human deaths each year, mainly in Asia and Africa. Despite its severity, rabies is 100% preventable through timely vaccination and awareness.
References:
World Health Organization (WHO):
WHO fact sheet on rabies, providing key facts and information on symptoms, diagnosis, transmission, post-exposure prophylaxis, local treatment, prevention, WHO response