16/11/2022
1. A 6-year-old boy presents to his pediatrician
with skin lesions all over his body. For several
years he has been very sensitive to sunlight.
Neither the boy's parents nor his siblings have
the same skin lesions or sun sensitivity. Biop-
sies of several of the boy's lesions reveal
squamous cell carcinoma. Which mutation
would one expect to see in this patient's DNA?
(A) Methylation of the gene
(B) Missense mutation in the gene
(C) Nonsense mutation in the middle of the
gene
(D) Point mutation within the enhancer region
(E) Point mutation within the operator region
(F) Point mutation within the promoter region
(G) Thymidine dimers
