Oroboros Instruments

Oroboros Instruments Oroboros Instruments distributes the gold standard for O2k-technology High-Resolution Respirometry. We are a scientifically oriented organization.

The oxygen solubility factor of the respiratory medium 𝘍M depends on temperature and medium composition. In MiR05 and Mi...
21/05/2026

The oxygen solubility factor of the respiratory medium 𝘍M depends on temperature and medium composition. In MiR05 and MiR06, 𝘍M is 0.92 (determined at 30 °C and 37 °C; assumed identical at 25 °C), while in culture media it is 0.89 (at 37 °C). For other media, 𝘍M can be estimated by treating KCl-based media as “seawater” of varying salinity.
Learn more: https://buff.ly/NT1im3x

The POS service manual describes how to perform cathode and anode cleaning, cleaning of electrical connections, and memb...
19/05/2026

The POS service manual describes how to perform cathode and anode cleaning, cleaning of electrical connections, and membrane mounting. These steps are essential to ensure signal stability, low noise, and high time-resolution.
https://buff.ly/0wo3DaZ

Last week, three of our team members took part in the Innsbruck Alpine Trailrun Festival and achieved 3ʳᵈ place in the ...
06/05/2026

Last week, three of our team members took part in the Innsbruck Alpine Trailrun Festival and achieved 3ʳᵈ place in the Women’s Business Trail!🥉
A great example of mitochondria in action — in research and on the trail.

Congratulations to Team Oroboros LAB - Lisa, Ana and Bente! 🎉

We are delighted to share that we will be presenting at several upcoming events this May and June. Discover our latest r...
05/05/2026

We are delighted to share that we will be presenting at several upcoming events this May and June. Discover our latest research and connect with our team - we look forward to meeting you. Here's where you can find us:

📍 EUROMIT 2026, Angers FR | May 31 – June 4
Diagnostic OXPHOS Precision Analysis with Cryopreserved PBMCs – Poster presentation by Alejandro Romero Martinez
Optimization of Human PBMC Isolation to Preserve Viability and Mitochondrial Function for Diagnostic Applications - Poster Presentation by Jaime Willis
More information: https://buff.ly/V1Mesme

📍 IBEC 2026, Roanoke VA US | June 1 – 6
Mitochondrial Ca²⁺ uptake is constrained in an exercise-mimicking model of functional hypoxia – Poster presentation by Elettra Leo
More information: https://buff.ly/qWaJbbj

📍 SFRR-E Meeting, Mainz DE | June 3 – 5
Oxygen dependence of hydrogen peroxide production in isolated mitochondria and permeabilized cells – Poster presentation by Sabine Schmitt
More information: https://buff.ly/rQufWxY

📍 GIBB 2026, Udine IT | June 11 – 13
Challenges of functional diagnostics in mitochondrial physiology – Keynote lecture by Erich Gnaiger
More information: https://buff.ly/vYLP4Cq

To clear a clogged needle, insert the provided cleaning wire to remove the blockage, then flush the syringe several time...
01/05/2026

To clear a clogged needle, insert the provided cleaning wire to remove the blockage, then flush the syringe several times with the appropriate solvent. If needed, soak it overnight in a flask of deionized or double-distilled water.
👉️ Find more information in our Microsyringe-Manual: https://buff.ly/EejG8VD

Thank you to everyone who visited our booth at the Long Night of Research in Innsbruck last Friday!We had a great time s...
28/04/2026

Thank you to everyone who visited our booth at the Long Night of Research in Innsbruck last Friday!

We had a great time sharing insights into why mitochondria and proteins are so central to the human body, and discussing our current research, including the MitoDrugs project in collaboration with KinCon biolabs.

We really appreciated all the engaging conversations and your interest in our work!

See more photos: https://buff.ly/3uzewaF

Oroboros Manual Chapter 1.4. describes the volume calibration—done after chamber assembly and with your experiment-speci...
27/04/2026

Oroboros Manual Chapter 1.4. describes the volume calibration—done after chamber assembly and with your experiment-specific stopper (single-port or multisensor design) to ensure accurate normalization of experimental flux.
📖 https://buff.ly/03wGmpA

Stubborn colored layers on the cathode?Does the cathode remain dirty after polishing with the cloth and powder? If a stu...
24/04/2026

Stubborn colored layers on the cathode?
Does the cathode remain dirty after polishing with the cloth and powder? If a stubborn colored layer persists, apply a drop of 50–75 % nitric acid solution for no more than 15 seconds. Rinse thoroughly with distilled water.
Learn more 👉https://buff.ly/eeloRMD

🟨 Ready, Set, Respire: Your Oroboros Experiment Starts Here!Get your high-resolution respirometry experiment off to a fl...
23/04/2026

🟨 Ready, Set, Respire: Your Oroboros Experiment Starts Here!
Get your high-resolution respirometry experiment off to a flawless start with this essential Oroboros checklist—covering setup, calibration, and key preparation steps. Follow these guidelines to ensure accurate results and smooth operation from the very first measurement.
📋https://buff.ly/o9gTSUl

High signal at zero oxygen? If you observe a high signal at zero oxygen during the O₂ zero calibration despite injection...
20/04/2026

High signal at zero oxygen?
If you observe a high signal at zero oxygen during the O₂ zero calibration despite injection of an excess volume of a freshly prepared dithionite solution, run the leak current test to identify which component is causing the elevated R0 signal.
Learn more about it 👉 https://buff.ly/tpziMKL

The isolation and cryopreservation of human peripheral blood mononuclear cells (PBMCs) necessitate standardized methodol...
17/04/2026

The isolation and cryopreservation of human peripheral blood mononuclear cells (PBMCs) necessitate standardized methodologies to ensure comparability across laboratories and studies. Romero et al. describe an optimized workflow for PBMC isolation and cryopreservation that emphasizes the reduction of platelet contamination and the preservation of cell viability and functional integrity for high-resolution respirometry.
Read the preprint 👉 https://buff.ly/eXSgvD6

Medizinische Universität Innsbruck

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