Dr. Ralf Kleef - Immunotherapy

17/08/2022

HUGE DISCOUNT FOR THE NEXT 48 HOURS
Lindsay McDonell is one of dr. Kleef’s great success stories. Today she released her book that documents her story with cancer including her time spent in the Kleef Clinic called Your Dance with Cancer. You can find it at https://linktr.ee/yourdancewithcancer

10/01/2022

Dear Friends, Patients, and Colleagues,
Please be informed about the details of the Funeral.
If you wish to participate please let us know at the office@dr-kleef.at email address.

31/12/2021

The Team of Dr Kleef Medical Center is wishing all of You a Happy New Year filled with health, happiness, prosperity and success!🥂💫

06/12/2021

Dr. Kleef’s Team wishes a Happy Saint Nicholas Day to Everyone! 🎅🏻🎁✨

02/12/2021

✨Right Nutrition, Strong Immunity✨

The main tasks of the body’s immune system are to fight disease-causing germs (pathogens) like bacteria, viruses, parasites or fungi, and to remove them from the body, and to fight disease-causing changes in the body, such as cancer cells.

Therefore choosing a variety of nutrients and eating healthy helps strengthen your body’s immune system. Here are some must-haves to boost your immunity:

🍋 Citrus fruits – The high vitamin C content in citrus fruits helps increase the production of white blood cells, which are key to fighting infections. Such as oranges, grapefruits, kiwi, and tangerines. They are rich in antioxidants (citrus bioflavonoids) which helps to neutralize free radicals.

🥦 Broccoli – Broccoli is packed with vitamins A, C, and E, as well as fibre and many other antioxidants. It is one of the healthiest vegetables and must be lightly cooked.

Turmeric – It contains strong anti-inflammatory agents like curcumin, demethoxycurcumin and bisdemethoxycurcumin. Turmeric is excellent against free radicals and inflammation.

Ginger – Since ages, ginger has been used for medicinal purposes, due to its rich nutritional properties. It is also great against nausea.

🧄 Garlic – Its immune-boosting properties seem to come from a heavy concentration of sulfur-containing compounds, such as allicin.

🌱 Spinach -Spinach is packed with numerous antioxidants and beta carotene, which helps increase the infection-fighting ability of your immune systems.

Yogurt – Yogurt is considered a probiotic that is essential to your immune system’s health. The good bacteria directly affects your gut, and helps improve your immunity.

☕️ Green Tea – Green tea contains excellent antioxidant properties that help the body detox toxins and other harmful elements.

29/11/2021

In order to have a consultation with Dr. Kleef (or his doctor colleague) the first step is to get in touch with us. Either via:
📱 Phone
📧 Email or
🌐 Website contact form.

📂The following documentations are required to be sent to us before the consultation:

-Relevant medical findings in order to analyze the medical history, and current health condition
-First and latest CT / MR / Ultrasound report
-Final diagnostic report
-Latest lab
-Biopsy report
-Histological result
-Already attended therapies.

Based on the received information and documentations Dr. Kleef is creating an anamnesis.
In the 45 minutes of Skype video consultation this document is being discussed together with a preliminary treatment suggestion and schedule.

Within 24 hours after the consultation with Dr. Kleef, our Coordination Team gets in contact with the patient via email. The Team sends the anamnesis document, any additional information noted down on the consultation, cost calculation with the preliminary treatment suggestion, and information of the treatment types and procedures. The Team also offers 2 starting dates. And taking into account the current Covid-19 circumstances we send all the in-travel information.

For further information please see our website:
🌐 https://drkleefimmuneoncology.com/

25/11/2021

✨ What is the super power of one of our treatments, the Whole Body Hyperthermia? ✨

🌡 By increasing the body temperature, the body activates strong self-healing powers and thus accelerates recovery over the long term.

💡 Hyperthermia is the targeted increase in the core body temperature. It is considered to be one of the most effective therapeutic methods in physical medicine.

🩺 Using hyperthermia to treat cancer requires collaboration between various professionals such as oncologists, radiation therapists, surgeons, general practitioners, immunologists, medical physicists, engineers and other professionals who help the doctor treat the patient, especially the radiology technician and, last but not least, the nurse.

Central mechanism of action of hyperthermia: The regulation of the basic system (matrix). Hyperthermia initiates a fever-like state and thus causes an intensive, sustained increase in core body temperature.

In this way, hyperthermia activates the body’s natural healing powers.

It clearly supports the so-called extravasation (trafficking of immunocompetent cells in the organism into the tumors areas) of lymphocytes (immune cells), modulates the complex cytokine network (hormones of the immune system) by switching them from a protective to a tumor attacking mode (e.g. M1/M2 switch), and also most importantly to increase the efficiency of chemotherapy, radiation and immunotherapy. In cases of tumor fatigue and exhaustion shorter and milder forms of whole-body hyperthermia have proven to be powerful measures to improve quality of life and fight cancer fatigue.

For further information please see our website:
🌐 https://drkleefimmuneoncology.com/

19/11/2021

Staying on a healthy weight and lifestyle helps to lower the risk of stomach cancer.

Here are some advices how to take care of your health:
🏃‍♂️ regular physical activity
😴 7-9 hours of sleep
🥬 eating wide range of fresh vegetables, and fruits
🍞 eating whole grain products, such as whole grain bread, cereals, pasta and rice
🚫 avoiding red and processed meats, highly processed, salty foods and sugar-sweetened beverages
🚭 avoiding alcohol and smoking
💦 drinking 3 l of water
🌱 drinking green tea, which helps the body’s metabolism

❗️Always remember that keeping healthy is a key part of our life. It is a long-term decision, which brings benefits to our life from several aspects.

16/11/2021

✨How has this long journey of the Founder, Dr. Kleef, started?✨

When Dr. Kleef was 19 years old, he met a large group of native American Indians at an NGO conference at the United Nations in Geneva. He was introduced to the sacred ceremony of the Indian sweat lodge. This was far more than a sauna and he was deeply impressed by the power of the heat.

Years later as a medical student again Dr. Kleef was drawn to the phenomenon of heat from another perspective: mistletoe therapy. Rudolf Steiner recognized cancer as an illness of the cold where the beneficial body heat (fever) is missing.

In the early 90s when Dr. Kleef started his education as an oncologist at the first German Hospital that used hyperthermia in cancer treatment he felt this to be his destiny as a scientist and medical doctor: To explore the possibilities of heat and fever in oncology.

After he finished his training in oncology he, therefore, chose to train as an immunologist. He became a close friend of Helen Coley-Nauts, a distinguished research scientist, whose father was William B. Coley, named to be the father of Cancer Immunotherapy.

In 2015 the discovery and later on Nobel prize for medicine for the detection of immune Checkpoint inhibitors brought him to the idea to combine the latter with all types of fever treatment in cancer: Local regional hyperthermia, whole-body hyperthermia and direct fever treatment with IL-2 (a powerful immunostimulatory cytokine capable of inducing fever).

This combined concept may be looked upon as a future possible breakthrough treatment in cancer treatment. Dr. Kleef and his Medical Team continue actively exploring scientifically and clinically the fascinating aspects of this multimodal treatment with a growing number of unusually successfully treated patients.

For further information visit our website:
🌐 https://drkleefimmuneoncology.com/

28/09/2021

Our mission is to support patients with neoplastic & other chronic illnesses on their healing journey with the best of our heart, knowledge, and decades of experience. 👨‍⚕️💛

Our innovative, unique, and individualized therapy concept is based on immunotherapy combined with hyperthermia treatments in an integrated therapy approach. ‍⚕️🏥
Contact us for consultation 🧬✅ https://drkleefimmuneoncology.com/

Our mission is to support patients with neoplastic & other chronic illnesses on their healing journey with the best of our hearts and decades of experience.

24/09/2021

🎬Join us for watching Dr. Ralf Kleef's new weekly video series.
In this series, Dr. Kleef will talk about immunotherapy and other treatments we provide, our best cases and results, and many interesting topics in our field. Stay tuned!
https://youtu.be/0jHx912YbCs

Dr. Ralf Kleef, MD talks about our unique therapy approach. Feel free to join us on Facebook and follow us here to watch the upcoming video series.

21/09/2021

Curcumin is a bioactive secondary metabolite in turmeric, which is widely used in traditional medicine due to its antioxidant, anti-cancer, and anti-inflammatory properties. The last one makes it a potential new agent in the treatment of COVID-19. Curcumin was found to reduce the viral load and modulate the cytokine-mediated inflammatory pathway involving IL-6, TNFα / NF-kβ, thereby suppressing the “cytokine storm”, significantly reducing morbidity and mortality in COVID 19. Curcumin infusions are also essential parts of Dr. Kleef´s biological treatment plan using it as a potent natural anti-cancer agent. Following chemosensitivity testing (TCA – tumor chemosensitivity assay) it will be determined whether cancer cells are sensitive or not to curcumin. If so, the starting dose is 150 mg, which will be increased to 300 mg, later on, infusions are applied 2-3 times per week.
Curcumin is a bioactive secondary metabolite in turmeric, which is widely used in traditional medicine due to its antioxidant, anti-cancer, and anti-inflammatory properties. The last one makes it a potential new agent in the treatment of COVID-19. Curcumin was found to reduce the viral load and modulate the cytokine-mediated inflammatory pathway involving IL-6, TNFα / NF-kβ, thereby suppressing the “cytokine storm”, significantly reducing morbidity and mortality in COVID 19.
Curcumin infusions are also essential parts of Dr. Ralf Kleef - Immunotherapy´s biological treatment plan using it as a potent natural anti-cancer agent. Following chemosensitivity testing (TCA – tumor chemosensitivity assay) it will be determined whether cancer cells are sensitive or not to curcumin. If so, the starting dose is 150 mg, which will be increased to 300 mg, later on, infusions are applied 2-3 times per week.

Coronavirus disease 2019 (COVID-19) is an infectious disease that rapidly spread throughout the world leading to high mortality rates. Despite the knowledge of previous diseases caused by viruses of the same family, such as MERS and SARS-CoV, management and treatment of patients with COVID-19 is a c...

20/09/2021

Our new branded website has been launched. Feel free to subscribe to our newsletter to keep yourself updated with the latest news, articles, videos, announcements, publications, and patient stories.
https://drkleefimmuneoncology.com/

Medicus curat Natura Sanat Doctor treats, nature heals Our mission is to support patients with neoplastic & other chronic illnesses on their healing journey with the best of our heart, knowledge and decades of experience. Our innovative, unique and individualized therapy concept is based on immunoth...

17/09/2021

Dr. Kleef speaks about a case of a young patient, who had vocal cord cancer and was treated with Low-Dose Ipilimumab Plus Nivolumab Combined With Interleukin-2 and Hyperthermia at our Clinic. The study of the case is published on Cureus: cureus.com/articles/53302
https://www.youtube.com/watch?v=yAd2M1hUPz4

Dr. Kleef tells about the case of Michael Silva Kutalek, who had vocal cord cancer at 44 years old, and was treated at our Clinic. Let us share his words abo...

08/09/2021

We proudly share that one of the most eminent immunology journals is citing our work (reference #127).
This article emphasizes the importance of the tumor microenvironment during the therapy with immune checkpoint inhibitors (ICI-s), which can be modulated in a positive way through the application of hyperthermia (artificial fever). The synergetic effect of these treatments also plays a key role in Dr. Kleef´s concept, who is applying both loco-regional and whole-body hyperthermia in combination with checkpoint-inhibitors Ipilimumab and Nivolumab. To explore more about Dr. Kleef´s unique therapy concept, tune in these next weeks to watch short explanatory videos by the doctor himself.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680736/