CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences At the center of CeMMโ€™s interest are patients and associated diseases.

CeMM integrates basic research and clinical expertise to pursue innovative diagnostic and therapeutic approaches focused on cancer, inflammation and immune disorders.

๐Ÿ“ข ๐—”๐—ฝ๐—ฝ๐—น๐˜† ๐—ณ๐—ผ๐—ฟ ๐˜๐—ต๐—ฒ ๐—”๐—œ๐—ง๐—›๐—ฌ๐—ฅ๐—”โ€“๐—–๐—ฒ๐— ๐—  ๐—œ๐—ป๐˜๐—ฒ๐—ฟ๐—ป๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐—ฎ๐—น ๐—ฃ๐—ต๐—— ๐—ฃ๐—ฟ๐—ผ๐—ด๐—ฟ๐—ฎ๐—บ!๐Ÿญ๐Ÿฑโ€“๐Ÿฎ๐Ÿฌ ๐—ณ๐˜‚๐—น๐—น๐˜† ๐—ณ๐˜‚๐—ป๐—ฑ๐—ฒ๐—ฑ ๐—ฃ๐—ต๐—— ๐—ณ๐—ฒ๐—น๐—น๐—ผ๐˜„๐˜€๐—ต๐—ถ๐—ฝ๐˜€ ๐—ถ๐—ป ๐—”๐—œ/๐— ๐—Ÿ ๐—ฎ๐—ป๐—ฑ ๐—Ÿ๐—ถ๐—ณ๐—ฒ ๐—ฆ๐—ฐ๐—ถ๐—ฒ๐—ป๐—ฐ๐—ฒ๐˜€ are...
07/25/2025

๐Ÿ“ข ๐—”๐—ฝ๐—ฝ๐—น๐˜† ๐—ณ๐—ผ๐—ฟ ๐˜๐—ต๐—ฒ ๐—”๐—œ๐—ง๐—›๐—ฌ๐—ฅ๐—”โ€“๐—–๐—ฒ๐— ๐—  ๐—œ๐—ป๐˜๐—ฒ๐—ฟ๐—ป๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐—ฎ๐—น ๐—ฃ๐—ต๐—— ๐—ฃ๐—ฟ๐—ผ๐—ด๐—ฟ๐—ฎ๐—บ!

๐Ÿญ๐Ÿฑโ€“๐Ÿฎ๐Ÿฌ ๐—ณ๐˜‚๐—น๐—น๐˜† ๐—ณ๐˜‚๐—ป๐—ฑ๐—ฒ๐—ฑ ๐—ฃ๐—ต๐—— ๐—ณ๐—ฒ๐—น๐—น๐—ผ๐˜„๐˜€๐—ต๐—ถ๐—ฝ๐˜€ ๐—ถ๐—ป ๐—”๐—œ/๐— ๐—Ÿ ๐—ฎ๐—ป๐—ฑ ๐—Ÿ๐—ถ๐—ณ๐—ฒ ๐—ฆ๐—ฐ๐—ถ๐—ฒ๐—ป๐—ฐ๐—ฒ๐˜€ are available in Vienna, Austria ๐Ÿ‡ฆ๐Ÿ‡น

๐Ÿ“… ๐——๐—ฒ๐—ฎ๐—ฑ๐—น๐—ถ๐—ป๐—ฒ ๐—ณ๐—ผ๐—ฟ ๐—ฎ๐—ฝ๐—ฝ๐—น๐—ถ๐—ฐ๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐˜€: ๐Ÿญ๐Ÿฌ ๐—ฆ๐—ฒ๐—ฝ๐˜๐—ฒ๐—บ๐—ฏ๐—ฒ๐—ฟ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฑ
โžก๏ธ https://apply.cemm.at/

โ€๐Ÿ”ฌ Are you a computer scientist, engineer, physicist, mathematician, medic, biologist, chemist, bioinformatician, or do you hold a degree in a similar subject?
Would you like to work on an exciting research project to improve human health?

We offer:
โœ… ๐Ÿฐ ๐˜†๐—ฒ๐—ฎ๐—ฟ๐˜€ ๐—ณ๐˜‚๐—ป๐—ฑ๐—ถ๐—ป๐—ด and ๐—ฒ๐—บ๐—ฝ๐—น๐—ผ๐˜†๐—บ๐—ฒ๐—ป๐˜ ๐—ฐ๐—ผ๐—ป๐˜๐—ฟ๐—ฎ๐—ฐ๐˜ (includes research costs and health insurance).
โœ… A ๐—ต๐—ถ๐—ด๐—ต๐—น๐˜† ๐—ถ๐—ป๐˜๐—ฒ๐—ฟ๐—ฎ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ introductory training program.
โœ… Full access to ๐˜€๐˜๐—ฎ๐˜๐—ฒ-๐—ผ๐—ณ-๐˜๐—ต๐—ฒ-๐—ฎ๐—ฟ๐˜ ๐˜๐—ฒ๐—ฐ๐—ต๐—ป๐—ผ๐—น๐—ผ๐—ด๐—ถ๐—ฒ๐˜€.
โœ… ๐—ฆ๐˜‚๐—ฝ๐—ฒ๐—ฟ๐˜ƒ๐—ถ๐˜€๐—ถ๐—ผ๐—ป ๐—ฏ๐˜† ๐˜๐—ผ๐—ฝ ๐˜€๐—ฐ๐—ถ๐—ฒ๐—ป๐˜๐—ถ๐˜€๐˜๐˜€ and support from the full CeMM and AITHYRA Faculty.
โœ… ๐—” ๐—ฃ๐—ต๐—— ๐—ฑ๐—ฒ๐—ด๐—ฟ๐—ฒ๐—ฒ ๐—ฎ๐˜„๐—ฎ๐—ฟ๐—ฑ๐—ฒ๐—ฑ ๐—ฏ๐˜† ๐˜๐—ต๐—ฒ ๐— ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐—ฎ๐—น ๐—จ๐—ป๐—ถ๐˜ƒ๐—ฒ๐—ฟ๐˜€๐—ถ๐˜๐˜† ๐—ผ๐—ฟ ๐—ง๐—ฒ๐—ฐ๐—ต๐—ป๐—ถ๐—ฐ๐—ฎ๐—น ๐—จ๐—ป๐—ถ๐˜ƒ๐—ฒ๐—ฟ๐˜€๐—ถ๐˜๐˜† ๐—ผ๐—ณ ๐—ฉ๐—ถ๐—ฒ๐—ป๐—ป๐—ฎ.
โœ… An ๐—ถ๐—ป๐˜๐—ฒ๐—ฟ๐—ป๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐—ฎ๐—น ๐—ฝ๐—ฟ๐—ผ๐—ด๐—ฟ๐—ฎ๐—บ in the heart of a scientifically active and culturally vibrant European city.

โญ CeMM is happy to have contributed once again, together with the ร–sterreichische Akademie der Wissenschaften (ร–AW), to ...
07/21/2025

โญ CeMM is happy to have contributed once again, together with the ร–sterreichische Akademie der Wissenschaften (ร–AW), to KinderuniWien! We created special online contentโ€”including a video, quiz, and memory gameโ€”for children to explore and understand what happens in the body when we get injured, and how wounds close and heal.

In the short video โ€œDie Blutbaustelle - Helfer im Einsatz!โ€, we show how blood platelets and white blood cells rush to a wound to repair the body and protect it from harm.

๐Ÿ”— The content is now freely accessible (in German) here: https://bit.ly/3IuoEI2

KinderuniWien (Children's University Vienna) gives kids aged 7 to 12 the opportunity to experience real university life for two weeksโ€”attending lectures, joining hands-on workshops, and meeting scientists across Viennaโ€™s major universities. This year, KinderuniWien took place from 7 to 18 July 2025, combining online content with live events.

We thank our colleagues Lisa Kleissl, Tatyana Tyschuk, Anna Hurt, and Wolfgang Dรคuble who created the educational online content, and we hope children will enjoy it and learn more about how our amazing bodies work! ๐Ÿ™

Ein blutendes Knie? Kein Problem, denn in deinem Kรถrper startet sofort der Superhelden-Einsatz! Im kurzen Video โ€žDie Blutbaustelle โ€“ Helfer im Einsatz!โ€œ zeigen wir dir, wie Plรคtti und die weiรŸen Blutkรถrperchen blitzschnell zur Wunde eilen, um dich zu schรผtzen und um alles zu reparieren.

Teresa Neuwirth, from the group of CeMM Adjunct PI and MedUni Prof. Georg Stary (Medizinische Universitรคt Wien), success...
07/17/2025

Teresa Neuwirth, from the group of CeMM Adjunct PI and MedUni Prof. Georg Stary (Medizinische Universitรคt Wien), successfully defended her PhD thesis today, entitled "Good cop gone bad: dysregulation of regulatory T cells in chronic skin inflammation."

Well done, Teresa! Congratulations from your colleagues and friends at CeMM! ๐ŸŽ“๐Ÿ‘๐ŸŽ‰

๐Ÿ“ธ Barbara Bachmann / CeMM

๐—œ๐—ฆ๐—– ๐—œ๐—ป๐—ป๐—ผ๐˜ƒ๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—ฆ๐—ต๐—ผ๐˜„๐—ฐ๐—ฎ๐˜€๐—ฒ ๐—ฎ๐—ป๐—ฑ ๐—ฆ๐˜‚๐—บ๐—บ๐—ฒ๐—ฟ ๐—˜๐˜ƒ๐—ฒ๐—ป๐˜ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฑ in Wรผrzburg ๐Ÿ‡ฉ๐Ÿ‡ชThank you to Miriam Unterlass, Fraunhofer Institute Director...
07/16/2025

๐—œ๐—ฆ๐—– ๐—œ๐—ป๐—ป๐—ผ๐˜ƒ๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—ฆ๐—ต๐—ผ๐˜„๐—ฐ๐—ฎ๐˜€๐—ฒ ๐—ฎ๐—ป๐—ฑ ๐—ฆ๐˜‚๐—บ๐—บ๐—ฒ๐—ฟ ๐—˜๐˜ƒ๐—ฒ๐—ป๐˜ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฑ in Wรผrzburg ๐Ÿ‡ฉ๐Ÿ‡ช

Thank you to Miriam Unterlass, Fraunhofer Institute Director and CeMM Adjunct PI, as well as to the ISC members, for introducing the science, innovation and achievements of the Fraunhofer-Institut fรผr Silicatforschung ISC with great commitment and style. Wishing you all the best in your future endeavors!

Find out more about the institute โžก๏ธ https://www.isc.fraunhofer.de/en.html

On 15 July 2025, CeMM PhD representatives organized the ๐—–๐—ฒ๐— ๐—  ๐—ฆ๐˜‚๐—บ๐—บ๐—ฒ๐—ฟ ๐—ฃ๐—ถ๐—ฐ๐—ป๐—ถ๐—ฐ, a relaxed and fun gathering in the CeMM cafe...
07/16/2025

On 15 July 2025, CeMM PhD representatives organized the ๐—–๐—ฒ๐— ๐—  ๐—ฆ๐˜‚๐—บ๐—บ๐—ฒ๐—ฟ ๐—ฃ๐—ถ๐—ฐ๐—ป๐—ถ๐—ฐ, a relaxed and fun gathering in the CeMM cafeteria and terrace to connect with colleagues and unwind.

CeMMies gathered to enjoy food, drinks, and nice conversations overlooking the beautiful cityscape of Vienna โ€” the perfect setting to exchange ideas, discuss projects, and strengthen our research community.

A big thank you to the PhD representatives for organizing such a pleasant evening! ๐Ÿ™Œ

๐Ÿ“ธ Chrysanthi Kagiou, Jan Leszczynski / CeMM

On 15 July 2025, Mariem Radhouani from the group of former CeMM PI and MedUni Vienna Prof. Sylvia Knapp (now in the grou...
07/15/2025

On 15 July 2025, Mariem Radhouani from the group of former CeMM PI and MedUni Vienna Prof. Sylvia Knapp (now in the group of Philipp Starkl, both Medizinische Universitรคt Wien) successfully defended her PhD thesis entitled "The impact of bacterial skin infection on allergic asthma development."

Well done, Mariem! Congratulations from your colleagues and friends at CeMM! ๐ŸŽ“๐Ÿ‘๐ŸŽ‰

๐Ÿ“ธ Laura Alvarez / CeMM

On 10 July 2025, CeMM hosted the ๐—ฉ๐—•๐—– ๐—ฆ๐˜‚๐—บ๐—บ๐—ฒ๐—ฟ ๐—ฆ๐—ฐ๐—ต๐—ผ๐—ผ๐—น ๐—ฒ๐˜ƒ๐—ฒ๐—ป๐˜, an inspiring afternoon of life sciences and connection. We wel...
07/11/2025

On 10 July 2025, CeMM hosted the ๐—ฉ๐—•๐—– ๐—ฆ๐˜‚๐—บ๐—บ๐—ฒ๐—ฟ ๐—ฆ๐—ฐ๐—ต๐—ผ๐—ผ๐—น ๐—ฒ๐˜ƒ๐—ฒ๐—ป๐˜, an inspiring afternoon of life sciences and connection. We welcomed the summer school students, including three who are currently in the labs of CeMM Principal Investigators Christoph Bock, Laura de Rooij, and Barbara Maier.

The event kicked off with a lecture by Christoph Bock, followed by a get-together over food, offering a chance to chat with Christoph and engage in lively discussions with fellow students on the CeMM terrace.

It was a great opportunity for the students to network and share ideas. Thank you to everyone who joined us, and we wish the students all the best in their summer research programme in Vienna! ๐Ÿงช๐Ÿ™Œ

๐Ÿ“ธ Matthew Spencer / CeMM

On 7โ€“8 July the CeMM Recess 2025 took place: a two-day retreat dedicated to our postdoc community.๐Ÿ‘ฉโ€๐Ÿ”ฌ๐Ÿ‘จ๐Ÿพโ€๐Ÿ”ฌThe retreat fea...
07/09/2025

On 7โ€“8 July the CeMM Recess 2025 took place: a two-day retreat dedicated to our postdoc community.๐Ÿ‘ฉโ€๐Ÿ”ฌ๐Ÿ‘จ๐Ÿพโ€๐Ÿ”ฌ

The retreat featured a dynamic mix of presentations, discussions, and creative sessionsโ€”exploring every stage of the postdoc journey, from publishing a paper to launching a future lab, daring to pitch wild, creative research ideas.

Set against the peaceful backdrop of Steinschalerhof ๐Ÿ‡ฆ๐Ÿ‡น, participants engaged in scientific talks, received valuable peer feedback, exchanged fresh perspectives, and explored potential collaborations, all while also enjoying a scenic hike and a fun evening quiz.

Special thanks to the organizers: CeMM P*s Barbara Maier and Abdel Rahman Abdel Fattah, and CeMM Adjunct PI Davide Seruggia, and to all CeMM colleagues who brought their energy, curiosity, and bold ideas to the event!

๐Ÿ“ธ Lukas Beck / CeMM

๐Ÿ”ฌ For the final   spotlight, we celebrate the backbone of CeMM: the ๐—”๐—ฑ๐—บ๐—ถ๐—ป๐—ถ๐˜€๐˜๐—ฟ๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—ฎ๐—ป๐—ฑ ๐—ฆ๐—ฐ๐—ถ๐—ฒ๐—ป๐˜๐—ถ๐—ณ๐—ถ๐—ฐ ๐—ฆ๐˜‚๐—ฝ๐—ฝ๐—ผ๐—ฟ๐˜ ๐—ง๐—ฒ๐—ฎ๐—บ!Under the...
07/03/2025

๐Ÿ”ฌ For the final spotlight, we celebrate the backbone of CeMM: the ๐—”๐—ฑ๐—บ๐—ถ๐—ป๐—ถ๐˜€๐˜๐—ฟ๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—ฎ๐—ป๐—ฑ ๐—ฆ๐—ฐ๐—ถ๐—ฒ๐—ป๐˜๐—ถ๐—ณ๐—ถ๐—ฐ ๐—ฆ๐˜‚๐—ฝ๐—ฝ๐—ผ๐—ฟ๐˜ ๐—ง๐—ฒ๐—ฎ๐—บ!

Under the leadership of CeMM Administrative Director Anita Ender, this team keeps our institute running by maintaining and constantly improving CeMMโ€™s technical, operational, educational, financial, and ethical infrastructure. Their work is essential to CeMMโ€™s success and ongoing commitment to research excellence. It lays the foundation for groundbreaking science, international collaboration, and continuous institutional growth.

Their equation of choice is Kirchhoffโ€™s theoremโ€”a principle from graph theory used to calculate the number of unique ways nodes in a network can be connected without creating loops. This reflects CeMM Administrationโ€™s vision: enabling efficient, dynamic, and non-redundant connections across the institute.

In 2024, the team played a central role in hosting the EU-LIFE Community Meeting, organizing the AI in the Life Sciences conference, and supporting the launch of AITHYRA Research Institute for Biomedical Artificial Intelligence, the new AI institute of the Austrian Academy of Sciences. From finance to HR, from tech transfer to trainingโ€”CeMMโ€™s Administration proves that strong science needs strong systems.

๐Ÿ”Ž Read more in the CeMM Research Report: https://tinyurl.com/CeMMRR2024-Admin

๐Ÿ“ธ Klaus Pichler / CeMM

๐—–๐—ผ๐—ป๐—ด๐—ฟ๐—ฎ๐˜๐˜‚๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐˜€ ๐˜๐—ผ ๐—–๐—ต๐—ฟ๐—ถ๐˜€๐˜๐—ผ๐—ฝ๐—ต ๐—•๐—ผ๐—ฐ๐—ธ, ๐—–๐—ฒ๐— ๐—  ๐—ฃ๐—ฟ๐—ถ๐—ป๐—ฐ๐—ถ๐—ฝ๐—ฎ๐—น ๐—œ๐—ป๐˜ƒ๐—ฒ๐˜€๐˜๐—ถ๐—ด๐—ฎ๐˜๐—ผ๐—ฟ ๐—ฎ๐—ป๐—ฑ Medizinische Universitรคt Wien, ๐—ผ๐—ป ๐—ฏ๐—ฒ๐—ถ๐—ป๐—ด ๐—ฒ๐—น๐—ฒ๐—ฐ๐˜๐—ฒ๐—ฑ ๐—ฎ๐˜€ ๐—ฎ ...
07/01/2025

๐—–๐—ผ๐—ป๐—ด๐—ฟ๐—ฎ๐˜๐˜‚๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐˜€ ๐˜๐—ผ ๐—–๐—ต๐—ฟ๐—ถ๐˜€๐˜๐—ผ๐—ฝ๐—ต ๐—•๐—ผ๐—ฐ๐—ธ, ๐—–๐—ฒ๐— ๐—  ๐—ฃ๐—ฟ๐—ถ๐—ป๐—ฐ๐—ถ๐—ฝ๐—ฎ๐—น ๐—œ๐—ป๐˜ƒ๐—ฒ๐˜€๐˜๐—ถ๐—ด๐—ฎ๐˜๐—ผ๐—ฟ ๐—ฎ๐—ป๐—ฑ Medizinische Universitรคt Wien, ๐—ผ๐—ป ๐—ฏ๐—ฒ๐—ถ๐—ป๐—ด ๐—ฒ๐—น๐—ฒ๐—ฐ๐˜๐—ฒ๐—ฑ ๐—ฎ๐˜€ ๐—ฎ ๐—ป๐—ฒ๐˜„ ๐—˜๐— ๐—•๐—ข ๐—บ๐—ฒ๐—บ๐—ฏ๐—ฒ๐—ฟ! ๐ŸŽ‰

EMBO honors Christoph for his outstanding contributions in biotechnology, bioinformatics, and molecular medicine. His groundbreaking research integrates experimental immunology and cancer biology with AI and machine-learning-powered computational methods to decode complex diseases and design immune-based therapies.

Election to EMBO membership is a prestigious lifetime honor, recognizing scientific excellence and promoting collaboration across a network of 2,100+ leading life scientists in Europe and beyond. Christophโ€™s election reflects both his international impact and the high scientific quality fostered at CeMM.

๐Ÿ”— Read more: https://bit.ly/4eluojm

๐Ÿ“ธ MedUni Vienna

๐Ÿง  Citrate is essential for the metabolism and development of neurons, and the membrane transport protein SLC13A5 plays a...
06/30/2025

๐Ÿง  Citrate is essential for the metabolism and development of neurons, and the membrane transport protein SLC13A5 plays a key role in this process. However, mutations in the SLC13A5 gene can lead to a severe form of epilepsy. But which mutations are involvedโ€”and how do they disrupt the transporterโ€™s molecular function and influence disease progression?

Building on data from the recently completed RESOLUTE and REsolution flagship projects, researchers at CeMM analyzed the effects of ~10,000 genetic mutations on SLC13A5 function. Their findings, published in Science Advances, shed new light on the mechanisms behind this diseaseโ€”laying the groundwork for future research and potential treatments for epilepsy and related conditions.

โžก๏ธ Read more: https://cemm.at/news/detail/how-a-faulty-transport-protein-in-the-brain-can-trigger-severe-epilepsy

๐Ÿ“„The Study โ€œLarge-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5โ€ was published in Science Advances on June 27, 2025. DOI: 10.1126/sciadv.adx3011
๐Ÿ”— https://www.science.org/doi/10.1126/sciadv.adx3011

๐Ÿ“ธ From L to R: Co-first author Wen-An Wang (ยฉ CeMM), senior author Giulio Superti-Furga (ยฉ Franzi Kreis/CeMM), and co-first author Evandro Ferrada (ยฉ CeMM).

โ˜€๏ธ ๐˜๐˜ณ๐˜ฐ๐˜ฎ ๐˜ต๐˜ฉ๐˜ฆ ๐˜š๐˜ถ๐˜ฏ๐˜ด๐˜ฉ๐˜ช๐˜ฏ๐˜ฆ ๐˜Š๐˜ฐ๐˜ข๐˜ด๐˜ต ๐˜ต๐˜ฐ ๐˜ด๐˜ถ๐˜ฏ๐˜ฏ๐˜บ ๐˜๐˜ช๐˜ฆ๐˜ฏ๐˜ฏ๐˜ข: we finished the week with the visit of ๐—Ÿ๐—ผ๐—ฐ๐—ต๐—น๐—ฎ๐—ป ๐—™๐—ฒ๐—ป๐—ป๐—ฒ๐—น๐—น from the University o...
06/27/2025

โ˜€๏ธ ๐˜๐˜ณ๐˜ฐ๐˜ฎ ๐˜ต๐˜ฉ๐˜ฆ ๐˜š๐˜ถ๐˜ฏ๐˜ด๐˜ฉ๐˜ช๐˜ฏ๐˜ฆ ๐˜Š๐˜ฐ๐˜ข๐˜ด๐˜ต ๐˜ต๐˜ฐ ๐˜ด๐˜ถ๐˜ฏ๐˜ฏ๐˜บ ๐˜๐˜ช๐˜ฆ๐˜ฏ๐˜ฏ๐˜ข: we finished the week with the visit of ๐—Ÿ๐—ผ๐—ฐ๐—ต๐—น๐—ฎ๐—ป ๐—™๐—ฒ๐—ป๐—ป๐—ฒ๐—น๐—น from the University of the Sunshine Coast, Australia, for an Impromptu Seminar hosted by CeMM PI Andrรฉ Rendeiro.

In his talk, โ€œ๐˜›๐˜ฉ๐˜ฆ ๐˜ด๐˜ฑ๐˜ข๐˜ต๐˜ช๐˜ข๐˜ญ ๐˜ญ๐˜ข๐˜ฏ๐˜ฅ๐˜ด๐˜ค๐˜ข๐˜ฑ๐˜ฆ ๐˜ฐ๐˜ง ๐˜ค๐˜ฐ๐˜ญ๐˜ฐ๐˜ณ๐˜ฆ๐˜ค๐˜ต๐˜ข๐˜ญ ๐˜ค๐˜ข๐˜ฏ๐˜ค๐˜ฆ๐˜ณ ๐˜ข๐˜ต ๐˜ด๐˜ช๐˜ฏ๐˜จ๐˜ญ๐˜ฆ-๐˜ค๐˜ฆ๐˜ญ๐˜ญ ๐˜ณ๐˜ฆ๐˜ด๐˜ฐ๐˜ญ๐˜ถ๐˜ต๐˜ช๐˜ฐ๐˜ฏ ๐˜ณ๐˜ฆ๐˜ท๐˜ฆ๐˜ข๐˜ญ๐˜ด ๐˜ฎ๐˜ฆ๐˜ค๐˜ฉ๐˜ข๐˜ฏ๐˜ช๐˜ด๐˜ต๐˜ช๐˜ค ๐˜ช๐˜ฏ๐˜ด๐˜ช๐˜จ๐˜ฉ๐˜ต๐˜ด ๐˜ช๐˜ฏ๐˜ต๐˜ฐ ๐˜ต๐˜ถ๐˜ฎ๐˜ฐ๐˜ถ๐˜ณ-๐˜ช๐˜ฎ๐˜ฎ๐˜ถ๐˜ฏ๐˜ฆ ๐˜ช๐˜ฏ๐˜ต๐˜ฆ๐˜ณ๐˜ข๐˜ค๐˜ต๐˜ช๐˜ฐ๐˜ฏ๐˜ดโ€, Lochlan shared insights into how his team explored the spatial organisation of the tumourโ€“immune microenvironment by profiling the expression of ~1,000 genes in nearly 850,000 cells across 23 tumour and normal colorectal tissue samples. They identified distinct cellular niches, revealing niche-specific shifts in chemokine signalling, T cell infiltration, and myeloid cell polarisation.

Lochlan Fennell is a computational biologist and group leader at the Biomedicine Discovery Institute, and currently heads the Oncogenic Aging Laboratory at the University of the Sunshine Coast, where he also leads the USCโ€“Griffith University Hub for Advanced Spatial Biology. His work is redefining how we visualise and understand tumour ecosystems.

Thank you, Lochlan, for an inspiring seminar and a very engaging and informative discussion with the CeMM community!

๐Ÿ“ธ Barbara Bachmann / CeMM

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CeMMโ€™s mission is to achieve maximum scientific innovation in molecular medicine to improve healthcare.

At CeMM, an international and creative team of scientists and medical doctors pursues free-minded basic life science research in a large and vibrant hospital environment of outstanding medical tradition and practice.

CeMMโ€™s research is based on post-genomic technologies and focuses on societally important diseases, such as immune disorders and infections, cancer and metabolic disorders.

CeMM operates in a unique mode of super-cooperation, connecting biology with medicine, experiments with computation, discovery with translation, and science with society and the arts.