ENDIA

Australia's largest study into the cause of type 1 diabetes. Recruitment to the study is now complete. Find out more at www.endia.org.au and Harry B.

Recruitment to the ENDIA Study has closed. The ENDIA (Environmental Determinants of Islet Autoimmunity) study is looking into what contributes to the development of Type 1 Diabetes in early childhood. Type 1 Diabetes in children is twice as common as it was 20 years ago. This is because our environment has changed and at-risk children are more likely to develop Type 1 Diabetes. If we can understand exactly what in the environment is harmful or protective, we can develop strategies to prevent Type 1 Diabetes. We believe that children are exposed to these environmental triggers very early in life, perhaps even before they are born. Accordingly, the ENDIA study has recruited 1511 participants across Australia from the pregnancy or up to 6 months of age that have a first-degree relative (i.e. baby's Mum, Dad or older sibling) with Type 1 Diabetes. ENDIA is an observational investigation and does not involve any study medications or treatments. Further information is available on the ENDIA website at www.endia.org.au. This research has been supported by JDRF Australia, JDRF-I, Australian Research Council Special Research Initiative in Type 1 Juvenile Diabetes and the Leona M. Helmsley Charitable Trust. Please note, comments and opinions made by others are not necessarily endorsed by the ENDIA Study Team. All content posted by the ENDIA Team has had ethical approval for public view. Thanks for your interest in finding the causes of Type 1 Diabetes!

06/09/2025

Naomi is 10! ! And although she came to visit ENDIA again and again, those visits have now come to an end. Naomi is joining over 150 graduates who have completed the ENDIA Study’s 10 years of follow-up.

All those p**ps, wees, swabs and blood tests are being processed or frozen in -80C freezers for future testing. What causes type 1 diabetes? We’re not sure yet, but we’re certainly on the road to finding out thanks to Naomi and all 1500 others who enrolled in the ENDIA Study. Thank you!

You can find all our current findings summarised and published on our website: https://www.endia.org.au/publications/

ENDIA does recommend graduates continue monitoring to adulthood (around 20 years of age) through Type1Screen www.type1screen.org . This is much less invasive and much less often if there are no antibodies. Also check out for the latest updates on . 💙

03/09/2025

Meet Valentina, the fearless flyer from who’s just hanging out above the loo like it’s totally normal. After providing a precious samples like **p 💩for ENDIA and the study with Dr Maddy, this photo seemed entirely sensible.

Physics? Optional.
Toilet humour? Mandatory. Thanks for visiting again, Valentina!

31/08/2025

🎉🧪 A big ENDIA congratulations to Zane on completing his final study visit!

From his very first check-up to his last , Zane has been a superstar; curious, brave, and always ready with a smile (and maybe a few questions for the scientists! 🧠✨).

Thank you, Zane, and to your family, for being such an important part of the ENDIA journey. Your contribution is helping us learn more about how develops and how we might one day prevent it. 💙

28/08/2025

🌟 Attention ENDIA Families! We Need Your Voice! 🌟

The ENDIA team is preparing several exciting grant applications for further funding. We would love to include the perspectives of our incredible ENDIA families. Your lived experiences are invaluable in shaping research that truly matters.

We’re developing projects that aim to:
1. 👶 Improve pregnancy and baby outcomes for mothers with .
2. 💾 Build a secure data repository for the terabytes of information already collected from the samples YOU provided, including , , , and much more. This could incorporate a participant portal allowing ENDIA families to access and engage with results arising from the study.
3. 🧬 Identify new early-life that may reveal additional risk or protective factors influencing whether a child develops islet autoimmunity and .
4. 🔍 Develop better ways to predict progression to type 1 diabetes among who have .

If you and/or your family would like to contribute your ideas and insights to help guide these projects, please reach out! 🙌
📩 Comment below, send us a DM, or email us at endia@adelaide.edu.au to express your interest, either generally or in a specific project above.

Your level of involvement can range from answering a few questions via email about your priorities for ENDIA researchers, through to participating in Zoom meetings, reviewing documents, and even being named as a contributor on ENDIA grants as a consumer researcher.

Together, we can make sure ENDIA research continues to reflect the voices and priorities of the families at its heart. 💙

25/08/2025

🧸✨ Today’s ENDIA is Mia from the — and she brought backup: her brave little Care Bear! 💪💖
With courage in one hand and cuddles in the other, Mia powered through her visit like a total champ. Whether it’s giving , getting measured, or flashing that superstar smile, Mia shows us what strength and sweetness look like.
Thank you, Mia (and Care Bear!), for helping us learn more about preventing . You're a hero in every way! 🌟

22/08/2025

🦠👶 Can Childhood Infections Trigger ?

The NSW ENDIA research team conducted a major new and . This combined data consisted of over 12 million participants! The review found a significant link between respiratory tract infections (RTIs) in early and an increased risk of developing .
📌 Key findings:
🔹 Childhood RTIs were associated with a 47% higher odds of developing T1D.
🔹 No consistent link was found between gestational (during ) RTIs and T1D in children.
🔹 More research is needed, especially using molecular testing, to understand how infections might influence autoimmune risk.
💡 This work adds weight to the idea that early-life environmental factors could shape long-term health, including the risk of all like T1D.
Read more at: https://doi.org/10.1016/j.eclinm.2025.103324

19/08/2025

Brilliant Beau and his brilliant mum came for his very final visit with the ENDIA Study Team. We can’t believe you are 10 years old already, Beau!

What a journey it has been with all the samples and information you have provided. We are hopeful we can use these to make a big contribution to finding , so we can find ways to prevent it in the future for all generations.

Thank you Beau! We couldn’t do it without you; without all of your ENDIA peers 🥰

16/08/2025

A large study from suggests that eating more pro-inflammatory foods during , like processed meats, fried foods, and sugary snacks, might slightly increase the risk of in .

Researchers followed over 67,000 pregnancies and found that for every increase in a mother’s "inflammatory diet score," the risk of in their child rose by 16%.

But here’s what’s important: is a complex . This study doesn't prove cause, and so many factors are out of our control.

💬 The real takeaway? We need better education and support for to access nourishing, fresh, less processed, anti-inflammatory foods.

Access the article at https://doi.org/10.1136/jech-2024-223320

13/08/2025

Today’s scientist is Aubree from !

Aubree showed keen interest in where all her samples went after she gave them to the ENDIA coordinator.

, Dex, showed Aubree how samples are processed in the lab, and where they are stored.

Could this be a future career for Aubree? Might she be one of the next generation of scientists helping to make ?

Thank you for your participation, Aubree!

10/08/2025

To all our ENDIA families, we’d like to share a message from ENDIA, Type1Screen and ATIC Investigator, Prof John Wentworth

"Hi Everyone! I wanted to communicate the exciting news that a trial aiming to prevent or delay the onset of will open later this year.
Around November 2025 we hope to open recruitment to a that will treat people with two or more diabetes antibodies and abnormal glucose with a tablet. There are also two TrialNet studies coming to Australia. More details will be available on the ATIC page and ther website: https://atic.svi.edu.au/, so keep checking in to these. The website also has the latest studies for all stages of available: https://breakthrought1d.org.au/clinical-trials/
If you haven’t had an ENDIA visit for some time, or have registered with but have not yet had the screening test you may like to consider actioning this soon.
Finally, if you know of other families living with who are yet to arrange screening please let them know that these new trials will provide access to promising therapies.
With best wishes
Prof John Wentworth"

07/08/2025

Here’s a little snapshot of the ENDIA coordinator team over the last few years. You will see some very familiar face and a few new.

Amazing SA nurse, Alison, received her 10 year research star medal at the recent ENDIA symposium, as did the awesome Alex from WA. This year we also welcomed Shivvangi to The Royal Melbourne Hospital Team.

We’d like to take a moment to thank all our past and present ENDIA Coordinators for all their care, dedication and skill.

04/08/2025

Today we’re celebrating 10‑year‑old Audra, who’s just completed her final ENDIA Study follow‑up; what an incredible achievement!

💙 Audra’s journey:
From the through to today, Audra and her family have shown remarkable dedication—turning up for blood and stool sample collections with positivity and teamwork, and faithfully providing answers to lots of questionnaires. Every piece of data she’s contributed brings us closer to understanding how starts and how we might stop it in its tracks.
🩸Audra’s Journey Highlights:
• Regular and 💩collections that have helped map early markers
• Parents’ insights on nutrition, health and wellbeing, giving vital context to the science
• A cheerful attitude that has inspired our research team at every visit
🤷‍♀️What’s Next:
With her follow‑up complete, Audra’s active participation in ENDIA ends—so this is a fond farewell to study visits! But she’ll always be part of the ENDIA family, and we look forward to sharing future findings made possible by her generosity. We do recommend graduates continue screening with Type1Screen Check out www.type1screen.org
😁Thank You, Audra!
Your courage, good humour and generous spirit have made a lasting difference. Here’s to you—for helping pave the way towards preventing for generations to come!💙

Address

Adelaide, SA

Website

http://www.endia.org.au/

Alerts

Be the first to know and let us send you an email when ENDIA posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Practice

Send a message to ENDIA:

Shortcuts

Featured

Kate Gardner Wellbeing & Colonics Adelaide
222 Old South Road, Old Reynella

Want your practice to be the top-listed Clinic in Adelaide?