26/02/2026
Can lung cancer cause syndromes?
Yes. Lung cancer can sometimes trigger syndromes that affect nerves, blood flow, or hormones, such as:
• Horner syndrome: symptoms include drooping eyelid, smaller pupil, reduced facial sweating, and shoulder pain
• Superior vena cava (SVC) syndrome: symptoms include swelling of the face, neck or arms, headaches or dizziness
• Paraneoplastic syndromes (SIADH, Cushing syndrome, hypercalcaemia): symptoms include fatigue, muscle weakness, nausea, appetite changes or confusion
These signs don’t mean lung cancer on their own, but if symptoms are unusual, persistent or unexplained, they’re worth checking.