Annointed Hands Soft Tissue Therapies

25/11/2025

Drink a Lot and You'll Gain a Lot

👉Drinking alcohol interferes with the body's weight regulation system by preventing adipose tissue (fat cells) from releasing fat for fuel. At the same time, alcohol's high calorie content easily creates a positive energy balance and increases fat storage. British researchers found that high alcohol consumption was associated with general body fat and to a greater extent abdominal fat deposition. Factors such as type of alcohol or the time of consumption (i.e., with or without meals) didn't affect the results. Drinking alcoholic beverages affects both sides of the energy equation (i.e., energy in and energy out). Every gram of alcohol has 7.5 calories - almost as much as fat. A typical 8-ounce beer has 150 calories. If you drink six beers, that's an extra 900 calories (3,500 calories make up 1 pound of fat). Also, that much beer inhibits your fat cells from releasing fat. Your gut starts to grow: you deposit fat rapidly from drinking extra calories, and you use less fat for fuel because alcohol inhibits fat breakdown. Consequently, you gain weight.
👀(Int J Obesity, 29:1436-1444)

25/11/2025

Growth Hormone Cuts Fat

👉Every bodybuilder on the planet knows that growth hormone (GH)
fights fat, but what do the studies tell Us? Danish researchers examined 19 human studies and several animal studies to assess the effects of growth hormone on obesity. Most of the larger studies found that growth hormone promoted weight and fat loss. The hormone was particularly effective for decreasing visceral fat. GH increases fat mobilization by inhibiting an enzyme called hormone-sensitive lipase and counteracting the effects of insulin in storing fat. The researchers speculated that manipulating the diet might be important for the optimum action of the drug. GH is extremely expensive and most studies used lower dosages than used by most bodybuilders. GH may be a more effective fat fighter at higher dosages.

👀(Metabolic Syndrome Related
Disorders, 4: 57-69)

24/11/2025

20/11/2025

MIGRAINE FIX REDUCES BODY FAT

👉Topiramate is used to treat migraine headaches. German researchers discovered that it also reduced body fat and enhanced metabolic health. They gave 100 milligrams of the drug per day to six patients for 20 weeks, which reduced body mass index (proportion of weight to height) by 7 percent, body fat by 12 percent, waist circumference by 4 percent, leptin (controls appetite and metabolic rate) by 39 percent and insulin resistance by 37 percent.
It increased adiponectin (helps control blood sugar and fat deposition) by 70 percent.
Topiramate decreased body fat and improved metabolic health.
👀(Experimental and Clinical
Endocrinology & Diabetes, published online)

20/11/2025

Drug Cuts Blood Supply to Fat Cells

👉Napoleon Bonaparte said that an army marches on its stomach. If he had been a biochemist, he might have said that fat cells get fatter by increasing their 🩸blood supply. A University of Cincinnati study on 🐁mice found that chemicals called propoptotic peptides promoted weight loss and decreased food intake by decreasing blood vessel density in the fat cells.
Fat cells have a rich blood supply.
Blood vessel density increases as people gain body fat. Each additional pound of fat tissue requires a mile of new blood vessels. Cutting the fat cells' blood supply starved the fat cells and reversed the fat-promoting effects of a high-fat, high-calorie diet. Fat loss resulted from a decrease in food intake, rather than an increase in energy expenditure.
The animals experienced no side effects from the treatment. Regulating fat cell blood supply with drugs might be an important way to prevent obesity.
👀(Diabetes, published online)

19/11/2025

Foods That Make You Fat

👉Diet is the key to weight control - and a study from Harvard 👨‍🔬University backs up what nutritionists and contest-prep gurus alike have been saying for years. Researchers that examined more than 120,000 people in a series of four-year increments found that people gained more than 3 pounds during each four-year period. Foods linked to weight gain ncluded potato chips (1.7 pounds), french fries (1.3 pounds), high-sugar drinks (1 pound), ed meat (1 pound) and processed meats (0.9 pounds). Foods that triggered long-term weight loss included vegetables (-0.2 pounds), whole grains (-0.4 pounds), fruits (-0.5 sounds), nuts (-0.6 pounds) and yogurt (-0.8 pounds). Increasing physical activity caused an average four-year weight loss of 1.8 pounds, while watching television increased weight y 0.3 pounds per hour per day. The best advice for long-term weight control is to eat a lean diet that includes more yogurt, nuts, fruits, whole grains and less red meat, and xercise more - and ditch the junk food such as potato chips, french fries and sweetened rinks if you haven't done so already.
👀(New England Journal of Medicine 364: 2392-2404)

19/11/2025

Crash Diets Mess Up Hormones

👉Dieting to lose weight causes serious changes in hormones controlling blood sugar, fat deposition, appetite and metabolic rate. Australian researchers measured hormones controlling appetite and metabolic rate in 50 overweight patients undergoing a 10-week weight-loss program. They also measured these hormones one year after the end of the study. Dieting had long-term effects on leptin, peptide Y Y cholecystokinin, insulin, ghrelin, gastric inhibitory polypeptide and pancreatic polypeptide. The test subjects also reported greater hunger levels one year after the study. Crash dieting causes long-term changes in factors controlling appetite and metabolic rate, which makes it extremely difficult to maintain weight loss.
👀(New England Journal of Medicine 365: 1597-1604)

18/11/2025

14/11/2025

Immune System Promotes Fat Burning

👉Bodyweight maintenance involves balancing caloric intake and expenditure.
Unfortunately, it's not as simple as that. The body has intricate control mechanisms that influence appetite and caloric expenditure. The brain and nerves release hormones called catecholamines that can speed up metabolic rate and fat burning. Catecholamines activate specialized tissue called brown fat that generates heat rather than storing energy as fat. Immune system cells called macrophages also release catecholamines that can activate brown fat and increase heat production and metabolic rate. Scientists are finding out that weight control is a complex process.
Each variable that controls weight is a target for possible medical therapies that can help people lose weight and body fat.
👀(Nature 480: 46-47)

14/11/2025

Free Radicals and Cell
Inflammation LINKED TO OBESITY

👉Oxidative stress (OS) is caused by the naturat production of free
"radicals, which are highly reactive chemicals produced naturally in the body during metabolism. It damages DNA and the protein and fat componënts of cells. OS is like biological ust that destroys cell membranes, disrupts, cell function, depresses immúne function, causes
Chronic low-grade inflammation and promotes aging. Obesity increases free radical formation and contributes to their health-destroying properties. Contributing factors include high blood sugar; high blood fats; high fat levels in tissues, inadequate antioxidant defenses, increased rates of freé radical formation, chronic inflammation and disrupted chemistry in the inner lining of blood vessels. Losing body fat through low calorie diets, exercist, weight-loss drugs or surgery reduces free radical damage to the cells. Leading a healthy lifestyle is the best way to promote a healthy, viable metabolism that can fight disease.
👀(Intérnational Journal Obesity, 30:400-418)