29/04/2025
Another discovery backing the power of our gut! If you have an autoimmune disease I would highly encourage you to address your gut health and lifestyle. It does require a holistic approach. For me I have seen remarkable differences in my health and blood test results by doing just that.
✓ What Happened - Scientists from the University of California, San Francisco and international collaborators have identified specific gut bacteria that appear to trigger or worsen multiple sclerosis. Published in Nature, their study analyzed gut microbiomes of MS patients and healthy individuals, discovering several bacterial strains significantly more abundant in people with MS.
These microbes stimulate immune responses directly linked to the disease, particularly by activating pro-inflammatory T cells. The researchers demonstrated causality by introducing these bacteria to mice with humanized immune systems, which subsequently developed MS-like inflammation in their central nervous systems. Conversely, when they removed or suppressed these bacteria, the inflammatory response decreased significantly.
💡 Why It's Important - This discoverychanges our understanding of MS, transforming it from a purely neurological disease to one with potential origins in gut microbial imbalance. For patients with this debilitating condition, this research might offer new pathways for intervention beyond current immunosuppressive therapies.
The findings suggest ways to perhaps treat MS but also prevent it in the future. This research adds to growing evidence that the gut microbiome significantly influences conditions previously considered unrelated to digestive health. It's interesting to note that good regulation in the nervous system, i.e. keeping stress and trauma low and well processed, is also linked with healthy gut bacteria balance.
♾️ The Takeaway - Throughout medical history in the West, we've often compartmentalized diseases by organ systems or individual causes, but this research continues to point to the value of a holistic approach. Whether it's environmental factors contributing to the loss of a healthy gut biome, or whether it is stress and unprocessed trauma, everything points back to focusing on the whole person when we think about preventing and treating disease.
Study: https://www.pnas.org/doi/10.1073/pnas.2419689122