19/10/2025
In a comprehensive analysis involving 700,000 patients with psoriasis across four countries, researchers found an increased risk for cancer overall and for multiple types of cancer.
Researchers conducted population-based cohort studies in four countries — Denmark, England, Israel, and Taiwan.
Psoriasis was associated with an overall 5% increased risk for cancer overall after adjustment for confounding factors. No association was observed between psoriasis and cancer in Denmark.
Significant associations were found for the following cancers: oral cavity (pHR, 1.29), pharynx (pHR, 1.30), oesophagus (pHR, 1.17), liver (pHR, 1.53), pancreas (pHR, 1.09), kidney (pHR, 1.19), Hodgkin lymphoma (pHR, 1.56), keratinocyte cancer (pHR, 1.37), non-Hodgkin lymphoma (pHR, 1.43), and leukemia (pHR, 1.61).
The researchers concluded that "these findings emphasize the need to reinforce cancer prevention strategies in the care of psoriasis patients so as to reduce the cancer burden.” (risk of cancer).
Cancer Thrivers
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An increased risk of cancer in psoriasis has been postulated, but the association remains incompletely understood. This study sought to examine the risk of