28/01/2026
In clinical practice, we often see a distinct pattern emerge during the transition into perimenopause—one that goes far beyond physical symptoms like hot flashes.
It is a subtle, yet profound, shift in how we process our environment and our relationships.
As progesterone levels begin to fluctuate and decline, we lose a vital neurological buffer. Progesterone is a key precursor to allopregnanolone, which modulates GABA receptors in the brain.
This is our primary "inhibitory" neurotransmitter—the one responsible for emotional regulation, patience, and the ability to process stress without entering a "fight or flight" response.
When this internal buffer thins:
👉🏻 Our threshold for sensory overload drops.
👉🏻 The nervous system remains in a state of high vigilance.
👉🏻 Communication that once felt easy can suddenly feel like a source of significant friction.
It is common for women to misinterpret this physiological shift as a personal or relational crisis. However, once we understand the neurochemical "why," we can move away from frustration and toward targeted support.
The scope of naturopathic care is to stabilise this internal environment. By supporting the nervous system and hormonal precursors, we don’t just address a "symptom", we help restore the capacity for calm, clear connection in your daily life. 🩵
Biology shapes our perspective. Let’s ensure yours is supported.
