MTHFR Support Global

MTHFR Support Global MTHFR Support Australia was created to provide support & raise awareness about MTHFR gene mutations & methylation. http://www.mthfrsupport.com.au

About MTHFR Support Australia:

Why did we decide to focus on MTHFR? Well we started to see more and more chronically ill people who had been to doctors , specialists and countless naturopaths and were just not getting the results they should have been. Individuals with a MTHFR mutation or disordered methylation are presenting with cardiovascular disease, chronic inflammation, depression, anxiety, Diabetes, autoimmune conditions, ADD/ADHD, Down's Syndrome, recurrent miscarriage and cancer- to name a few! We need to heal at a cellular level and what we now see is that nutritional methyl donors are restoring our patients health because we are breaking down the obstacles to healing and decreasing inflammation. We work with nutrition, co-factors and substrates required to bring the methylation cycle back into balance to reduce symptoms

Our learning always continues and it seems the more we know the more we need to know. We truly believe in a collaborative health care approach. The patient has to come first. We all have to try harder to ensure that sick people get better. We need to think outside the square and all put our heads together to ensure this works. We've seen this every day. We know this works. If you are a practitioner, join our PRACTITIONERS ONLY group: https://www.facebook.com/groups/MTHFRPractitionerMembersGroup

🧠 Mindful Monday: Mental health isn’t just in your headIf you’ve been feeling:• flat• anxious• emotionally reactive• dis...
08/02/2026

🧠 Mindful Monday: Mental health isn’t just in your head

If you’ve been feeling:
• flat
• anxious
• emotionally reactive
• disconnected
• or mentally exhausted

This isn’t a personal failure.
It’s often your nervous system asking for support.

Mental health isn’t about “thinking better thoughts”.
It’s about how safe, supported, and regulated your body feels.

🌿 A gentle mindful moment for today

Try this once today. No fixing, no forcing:
✨ Place one hand on your chest
✨ Notice one sensation in your body (warmth, tightness, ease, movement)
✨ Name it silently, without judgement

That’s it.

This kind of body-based awareness helps calm the stress response and creates space for emotional clarity, especially on days when your mind feels loud or heavy.

A reminder you might need

You don’t have to be positive to be healing.
You don’t have to push through to be strong.
You’re allowed to move slowly and still make progress.

💬 What’s your mental health needing more of right now: rest, support, boundaries, or gentleness?

Over the past couple of weeks, we’ve shared real case studies where genomics changed everything:• chronic fatigue that w...
05/02/2026

Over the past couple of weeks, we’ve shared real case studies where genomics changed everything:

• chronic fatigue that worsened with B-vitamins
• anxiety triggered by magnesium
• “leaky gut” that was actually a detox bottleneck
• unexplained fertility loss
• histamine intolerance that wasn’t histamine
• autoimmune flares that became predictable
• insomnia with normal sleep studies
• depression resistant to multiple medications
• chronic pain that wouldn’t switch off
• dozens of food sensitivities that weren’t food-related

Different symptoms.
Different diagnoses.
One common thread: genetic pathways were being missed.

Each of these cases improved once practitioners understood how the individual’s body processed nutrients, hormones, neurotransmitters, inflammation, and detoxification.

That’s exactly what the Functional Genomics Institute was created for: to give practitioners the skills and frameworks to stop guessing, stop cycling protocols, and start seeing patterns earlier.

⏰ Important timing note:
The annual membership is currently $270/year, but this price increases on February 7. After that, the same access and training will be $444/year.

Nothing changes except the price.

🔗https://loom.ly/4h4J1g4

If genomics has helped these cases make sense for you, imagine what it could do inside your own practice.

“When everything seems to trigger symptoms, look at the genetics, not the foods.”This case completely reframed how I vie...
04/02/2026

“When everything seems to trigger symptoms, look at the genetics, not the foods.”

This case completely reframed how I view severe food sensitivities.

A 35-year-old woman came in after 18 months of progressively worsening reactions.
Her diet had narrowed to rice, chicken, and a few vegetables. Yet she still experienced bloating, brain fog, joint pain, rashes, and crushing fatigue after every meal.

She wasn’t reacting to bad foods.
She was reacting to normal food chemistry.

🧬 Genomics revealed the missing layer:
Her body struggled to metabolise naturally occurring compounds found in most foods - histamines, phenols, salicylates, aldehydes, and amines - due to impaired detoxification and methylation pathways.

The result?
What appeared to be “47 food sensitivities” was actually metabolic overload, not a true allergy or leaky gut failure.

Once support shifted away from endless restriction and toward histamine handling, sulfation, methylation, and detox capacity, her tolerance began to return.

✨ Weeks later, foods came back.
✨ Months later, food fear disappeared.
✨ A year later, she was eating freely again.

🧠 Clinical reminder:
Extensive food reaction lists often reflect how the body processes foods rather than the foods themselves.

When elimination diets keep expanding, it’s time to look upstream.

❗FINAL OPPORTUNITY: Your chance to join the Functional Genomics Institute at or $29 p/m ends February 7th. After that date, the same comprehensive training jumps to $37 - now is your chance to save $174 more annually for the exact same genetic insights that solve complex cases like these.
👉https://loom.ly/4h4J1g4

🌿 Wellness Wednesday: Chronic pain is not “all in your head”If you live with chronic pain, you’ve probably been told to ...
03/02/2026

🌿 Wellness Wednesday: Chronic pain is not “all in your head”

If you live with chronic pain, you’ve probably been told to push through, stretch more, or that everything looks normal on your tests.

But chronic pain isn’t just a muscle or joint issue. It’s often a nervous system, inflammation and biochemistry issue.

Here’s what’s really happening 👇
🧠 Pain can become learned
When pain signals repeatedly fire, the nervous system can become hypersensitive, causing pain to persist even after tissues have healed.

🔥 Inflammation keeps the signal alive
Low-grade, chronic inflammation amplifies pain pathways and reduces your body’s ability to modulate them.

🧬 Genetics can play a role
Variations in genes like MTHFR, COMT, and others can affect how you process stress hormones, neurotransmitters, and inflammation, all of which influence pain perception.

😴 Poor sleep + stress = louder pain
When your body doesn’t rest or feel safe, pain thresholds drop even further.

🌱 A gentler way to support chronic pain

This isn’t about “doing more”, it’s about supporting the system behind the pain:
✨ Calm the nervous system (breathing, gentle movement, safety cues)
✨ Reduce inflammation through nutrition and lifestyle
✨ Support methylation & detox pathways
✨ Prioritise sleep and pacing
✨ Validate the experience, pain is real, even when scans are normal

💛 Chronic pain doesn’t mean your body is broken.
It means your system needs understanding, safety, and support.

💬 If you live with chronic pain, you’re not alone. What helps you most on hard days?

02/02/2026

🧠 When chronic pain isn’t about injury. It’s about amplification

This case completely changed how I think about chronic pain.

A 47-year-old woman developed widespread pain after a minor car accident.
What started as neck pain spread throughout her body and stayed for five years.

She did everything “right”: physio, massage, acupuncture, medications, and even daily opioids.
Nothing touched the pain long-term.

The big question was never “where is the pain coming from?”
It was “why won’t the body turn it off?”

🧬 Genetics revealed the missing layer.
Her profile showed variants affecting:
• pain signal processing
• opioid receptor response
• inflammation and cytokine activity
• detox and neurotransmitter pathways

In simple terms, her nervous system was amplifying pain instead of resolving it, and her medications were poorly matched to her biology.

Once support shifted from symptom suppression to genetic pain processing, inflammation regulation, and neuroplasticity, everything changed.

Weeks later, pain intensity softened.
Months later, opioids were reduced, then stopped.
A year later, she was hiking again.

✨ Clinical reminder:
Chronic pain that persists beyond normal healing time is often not “structural damage.”
It’s altered signalling, and genetics frequently explains why.

Understanding how the body processes pain can be the difference between lifelong management and real recovery.

Want to confidently solve cases like this, before protocols backfire?
That’s exactly what the Functional Genomics Institute Annual Membership teaches.
💡 Right now: $270/year
⏰ Price increases Feb 7 to $444/year

✔️ Save $174 every year
✔️ Lock in your lower rate for life
Master the genomic insights behind real clinical breakthroughs, without trial and error.
👉 https://loom.ly/4h4J1g4

Mindful Monday: how you eat matters as much as what you eatIf you’re eating “well” but still feel bloated, tired, or fog...
01/02/2026

Mindful Monday: how you eat matters as much as what you eat

If you’re eating “well” but still feel bloated, tired, or foggy.
This might be the missing piece.

👉 Your body can’t digest properly when it feels rushed or stressed.

Digestion isn’t just about food.
It’s a nervous system process.

🍽️ A 60-Second Mindful Eating Reset

Try this with your next meal or snack:
✨ Take one slow bite
✨ Put the fork down
✨ Chew until the texture changes
✨ Notice taste, temperature, and smell

That’s it.

This small pause helps activate the rest-and-digest response, improving digestion, nutrient absorption, and how your body handles food.

Why this matters
🧠 Stress diverts blood away from digestion
🍃 Calm supports enzyme release & gut motility
🧬 This is especially important for people with sensitivities, gut issues, or MTHFR-related overload

A gentle reminder

You don’t need a perfect diet.
You need a supported digestive system.

💬 Will you try one mindful bite today?

🧬 MTHFR isn’t the problem. It’s the ContextYou don’t have an MTHFR problem.You have a pathway that may need different su...
29/01/2026

🧬 MTHFR isn’t the problem. It’s the Context

You don’t have an MTHFR problem.
You have a pathway that may need different support.

MTHFR doesn’t decide your health outcomes. It influences how efficiently your body handles:
• folate
• methylation
• detoxification
• neurotransmitters
• hormones
• inflammation

For some people, MTHFR variants are completely silent.
For others, they help explain why stress hits harder, why certain supplements backfire, or why “standard” health advice doesn’t quite work.

❗The key point?
MTHFR never acts alone.

Nutrition, stress load, sleep, hormones, gut health, and other genes all determine whether it becomes relevant or stays quiet.

✨ Understanding MTHFR isn’t about labels or fear.
It’s about working with your biology instead of fighting it.

And that shift, from blame to context, changes everything.

🌿 A Gentle reminder (...not a push) 🌿If you’ve been feeling sluggish, bloated, or out of sync with your body lately, thi...
28/01/2026

🌿 A Gentle reminder (...not a push) 🌿

If you’ve been feeling sluggish, bloated, or out of sync with your body lately, this is your permission to pause and reflect.

Not to judge yourself.
Not to rush.
Just to notice.

Many people start the year telling themselves, “I’ll focus on my health soon.”
Soon becomes weeks.
Weeks become months.
And the body keeps asking for support.

The Feeling Fantastic Detox Program was created for people who’ve tried “doing all the right things” but whose bodies didn’t respond well to aggressive detoxes or one-size-fits-all plans.

It’s not about forcing change.
It’s about working with your body, gently and intelligently.

For the next 72 hours, the program is available at 50% off. After January 30, it returns to full price. No tricks. No extensions.

Access via link in the bio or click here: https://loom.ly/kMJhFi0

Whether you start now or later, the question is simply this:
✨ What does your body need right now? And are you willing to listen?

🧬 Wellness Wednesday: Genomics 101: What it is & why it mattersYou’ve probably heard the word genomics everywhere lately...
27/01/2026

🧬 Wellness Wednesday: Genomics 101: What it is & why it matters

You’ve probably heard the word genomics everywhere lately…
But what does it actually mean, and why is it showing up in wellness, mental health, and chronic illness conversations? 👀

Let’s break it down simply 👇
🧠 What Is Genomics?
Genomics is the study of how your genes interact with your environment.
Your genes are NOT your destiny.
They’re more like a set of instructions, and how they behave depends on things like:
🍽️ nutrition
😴 sleep
🧘 stress
🧪 toxins
🏃 movement
💊 medications

This is where genomics meets epigenetics, the science of turning genes up or down.

🧬 So how does genomics work in real life?
Certain genes influence how you:
• detox
• produce neurotransmitters
• manage inflammation
• regulate mood
• respond to stress
• process nutrients

For example, genes like MTHFR, COMT, MAOA, GST, and DAO can affect:
🧠 mental health
🔥 inflammation
😴 energy & sleep
🌱 nutrient needs

Genomics helps explain why the same diet, supplement, or lifestyle works for one person… but not another.

🌿 Why genomics matters for wellness
Instead of guessing, genomics helps you:
✨ personalise nutrition
✨ support mental health more effectively
✨ understand stubborn symptoms
✨ reduce trial-and-error
✨ work with your biology, not against it

It’s not about perfection; it’s about precision + compassion.

✨ Genomics doesn’t tell you what’s “wrong” with you.
It helps you understand what your body needs to thrive.

💬 Curious to learn more about your genes? This is just the beginning.

“I feel like a guinea pig.”That’s how this 31-year-old man described his experience after three years and seven failed a...
26/01/2026

“I feel like a guinea pig.”

That’s how this 31-year-old man described his experience after three years and seven failed antidepressants.
❌SSRIs.
❌SNRIs.
❌Tricyclics.
❌Atypicals.

Some did nothing.
Others made him worse.

His psychiatrist was preparing to discuss ECT. Not because he wasn’t trying, but because nothing was working.

And he was starting to believe the problem was him.

🔍 What the medication history really showed
His failed trials weren’t random side effects; they were clues:
• severe reactions at low doses
• no response even at maximum doses
• agitation, insomnia, sedation, cognitive fog
• worsening anxiety instead of relief

This wasn’t psychological resistance.
It was a pharmacogenetic mismatch.

🧬 What genomics revealed
His genetic profile explained everything:
• poor metabolism of most antidepressants
• reduced serotonin transporter activity
• impaired dopamine & catecholamine clearance
• significant methylation impairment

In simple terms:
👉 Most antidepressants couldn’t work properly in his body.
👉 Serotonin wasn’t the main issue; dopamine & noradrenaline were.

✨ The breakthrough
Once treatment aligned with his genetics rather than trial-and-error prescribing, the shift was profound.

Within weeks:
✅mental clarity returned
✅mood lifted
✅engagement came back

Months later, he was thriving again, socially, professionally, and emotionally.

🧠 Clinical pearl
“Treatment-resistant depression” is often not reresistant illness.
It’s reresistant medication choice.

When pharmacogenetics and neurotransmitter pathways are ignored, suffering is prolonged unnecessarily.

Genetics doesn’t replace care. It guides it before harm occurs.

Want to confidently solve cases like this, before protocols backfire?
That’s exactly what the Functional Genomics Institute Annual Membership teaches.
💡 Right now: $270/year
⏰ Price increases Feb 7 to $444/year

✔️ Save $174 every year
✔️ Lock in your lower rate for life
Master the genomic insights behind real clinical breakthroughs, without trial and error.
👉https://loom.ly/QEpA1PM

“I never know when the flare is coming.”That’s what this 42-year-old woman with Hashimoto’s told me after years of unpre...
22/01/2026

“I never know when the flare is coming.”

That’s what this 42-year-old woman with Hashimoto’s told me after years of unpredictable autoimmune flares, weight gain, brain fog, joint pain, crushing fatigue, despite ongoing thyroid medication adjustments.

Her tests looked normal between flares.
Her diet was consistent.
Nothing obvious explained the pattern.

But genetics did.

Her profile revealed a combination of immune susceptibility, inflammatory signalling, and poor stress-hormone clearance, creating a stress-triggered autoimmune flare pattern that looked random until it wasn’t.

Once we stopped reacting to flares and started anticipating them, everything changed.
By tracking stress load and supporting her genetic vulnerabilities before immune activation, flares became predictable and preventable.

🧠 Clinical insight:
Autoimmune flares aren’t always random.
When stress, inflammation, and immune regulation genetics intersect, patterns emerge, and prevention becomes possible.

Want to confidently solve cases like this, before protocols backfire?
That’s exactly what the Functional Genomics Institute Annual Membership teaches.
💡 Right now: $270/year
⏰ Price increases Feb 7 to $444/year

✔️ Save $174 every year
✔️ Lock in your lower rate for life
Master the genomic insights behind real clinical breakthroughs, without trial and error.

“All my tests are normal… so why can’t I sleep?”This was a 38-year-old woman with two years of severe insomnia, waking e...
21/01/2026

“All my tests are normal… so why can’t I sleep?”

This was a 38-year-old woman with two years of severe insomnia, waking every night at 2–3 am with racing thoughts, exhaustion the next day, and relying on caffeine just to function.

Sleep studies? Normal.
Cortisol rhythm? Normal.
Melatonin? Normal.
Mental health screening? Normal.

And yet, she hadn’t slept through the night in years.

This case was a powerful reminder that normal test results don’t always reflect normal physiology.

Genomic analysis revealed a very different story, one where dopamine, adrenaline, caffeine metabolism, GABA signalling, and melatonin sensitivity were all working against sleep.

Once her care shifted from “sleep hygiene” to supporting neurotransmitter metabolism and clearance, the pattern changed.

Within weeks, she was sleeping through the night again.

🧠 Clinical insight:
When insomnia persists despite normal testing, it’s often not a sleep problem. It’s a neurotransmitter clearance problem.

Genetics can reveal what standard testing misses.

🔔 SPECIAL ANNOUNCEMENT
Want to confidently solve cases like this, before protocols backfire?
That’s exactly what the Functional Genomics Institute Annual Membership teaches.
💡 Right now: $270/year
⏰ Price increases Feb 7 to $444/year

✔️ Save $174 every year
✔️ Lock in your lower rate for life
Master the genomic insights behind real clinical breakthroughs, without trial and error.

Address

40 Yeo Street
Crows Nest, NSW
2089

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Our Story

About MTHFR Support Global: Why did we decide to focus on MTHFR? Well we started to see more and more chronically ill people who had been to doctors , specialists and countless naturopaths and were just not getting the results they should have been. Individuals with a MTHFR mutation or disordered methylation are presenting with cardiovascular disease, chronic inflammation, depression, anxiety, Diabetes, autoimmune conditions, ADD/ADHD, Down's Syndrome, recurrent miscarriage and cancer- to name a few! We need to heal at a cellular level and what we now see is that nutritional methyl donors are restoring our patients health because we are breaking down the obstacles to healing and decreasing inflammation. We work with nutrition, co-factors and substrates required to bring the methylation cycle back into balance to reduce symptoms Our learning always continues and it seems the more we know the more we need to know. We truly believe in a collaborative health care approach. The patient has to come first. We all have to try harder to ensure that sick people get better. We need to think outside the square and all put our heads together to ensure this works. We've seen this every day. We know this works.