MTHFR Support Global

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MTHFR Support Global

MTHFR Support Australia was created to provide support & raise awareness about MTHFR gene mutations & methylation. http://www.mthfrsupport.com.au

About MTHFR Support Australia:

Why did we decide to focus on MTHFR? Well we started to see more and more chronically ill people who had been to doctors , specialists and countless naturopaths and were just not getting the results they should have been. Individuals with a MTHFR mutation or disordered methylation are presenting with cardiovascular disease, chronic inflammation, depression, anxiety, Diabetes, autoimmune conditions, ADD/ADHD, Down's Syndrome, recurrent miscarriage and cancer- to name a few! We need to heal at a cellular level and what we now see is that nutritional methyl donors are restoring our patients health because we are breaking down the obstacles to healing and decreasing inflammation. We work with nutrition, co-factors and substrates required to bring the methylation cycle back into balance to reduce symptoms

Our learning always continues and it seems the more we know the more we need to know. We truly believe in a collaborative health care approach. The patient has to come first. We all have to try harder to ensure that sick people get better. We need to think outside the square and all put our heads together to ensure this works. We've seen this every day. We know this works. If you are a practitioner, join our PRACTITIONERS ONLY group: https://www.facebook.com/groups/MTHFRPractitionerMembersGroup

21/12/2025

🎄 Mindful Monday: Christmas Edition 🎄

Mindful Monday reminder:
Christmas doesn’t have to be perfect to be meaningful.

Between busy schedules, social expectations, and sensory overload, this season can feel like a lot — especially if you’re already managing stress, fatigue, or health challenges.

✨ This week’s gentle invitation:
• Slow your pace where you can
• Choose rest without guilt
• Honour your boundaries
• Focus on what feels nourishing, not obligatory

Mindfulness at Christmas isn’t about doing more rituals.
It’s about noticing what your nervous system needs, and responding with kindness. 🤍

Take a breath. You’re allowed to do this season your way.

18/12/2025

🌿 Folate: A Small Nutrient with a Big Job 🌿

Folate isn’t just a “pregnancy vitamin”. It’s a foundational nutrient involved in some of your body’s most important processes, every single day. 🧬

🔍 What does folate actually do?
Folate supports:
🧬 DNA synthesis & repair (essential for cell division)
🩸 Healthy red blood cell production
🌱 Normal cell growth and tissue repair
♻️ Methylation — a key pathway for detoxification, hormone balance & nervous system health

🤰 Why folate matters before and during pregnancy
Adequate folate status is associated with a reduced risk of:
🚼 Neural tube defects (e.g. spina bifida)
❤️‍🩹 Certain pregnancy complications
👶 Some congenital abnormalities

This is why folate sufficiency is recommended before conception, not just after a positive test.

⚠️ Folate vs Folic Acid. Not the same thing
These terms are often used interchangeably, but they’re very different:
• Folate = naturally occurring, biologically active
• Folic acid = synthetic form that must be converted in the body

For individuals with reduced folate-converting capacity (including some with MTHFR variants), this conversion may be less efficient.
👉 That’s why many practitioners recommend methylfolate (L-5-MTHF) — the active form the body can use directly.

✨ The key takeaway
Folate isn’t about “more is better”. It’s about the proper form, at the correct dose, for the right person.
Personalised nutrition matters.

💬 Curious about folate, methylation, or which form may be right for you?
Drop your questions below, we’re here to help.

17/12/2025

🌿 Serotonin: More Than a “Feel-Good” Chemical 🌿

Serotonin plays a vital role in mood, sleep, digestion, motivation, and nervous system balance. While it’s often simplified as the “happy hormone,” serotonin is actually a complex signalling molecule influenced by nutrition, gut health, stress, inflammation, hormones, and genetics. 🧬

When serotonin pathways are disrupted, both mental and physical symptoms can appear.

⚠️ What can interfere with healthy serotonin balance?
🍽️ Nutrition & gut health
Serotonin is made from tryptophan, an amino acid found in protein-rich foods.
Poor dietary intake, restrictive eating, or an imbalanced gut microbiome can reduce serotonin synthesis, as most serotonin is produced in the gut.

🦠 Digestive dysfunction
Gut infections, chronic GI conditions, surgery, or ongoing inflammation can impair serotonin production and signalling, reinforcing the gut–brain loop.

😰 Chronic stress & unresolved trauma
Long-term stress elevates cortisol, which can suppress serotonin activity over time, contributing to anxiety, low mood, poor sleep, and emotional dysregulation.

🌞 Low sunlight & limited movement
Sunlight exposure and regular physical activity both stimulate serotonin pathways.
Reduced exposure (especially in winter) may contribute to fatigue, low mood, or seasonal changes in mental health.

💊 Certain medications
Some medications can alter serotonin production, metabolism, or receptor activity. Effects vary widely and depend on the individual and overall biochemical context.

🧬 Genetic influences
Variants in genes involved in serotonin transport and metabolism (such as SLC6A4) can affect how serotonin is produced, recycled, or utilised, influencing stress sensitivity and mood regulation.

🔥 Inflammation & immune activation
Chronic inflammation, particularly in the gut, can divert tryptophan away from serotonin production and inflammatory pathways (such as the kynurenine pathway), reducing serotonin availability.

💡 Hormonal shifts
Hormonal changes (e.g. pregnancy, menopause, thyroid imbalance) can significantly influence serotonin synthesis and receptor sensitivity.

✨ The key takeaway
Supporting serotonin isn’t about boosting one chemical. It’s about supporting the whole system:
🥗 Nutrient sufficiency
🦠 Gut health
🌿 Inflammation balance
☀️ Light & movement
🧠 Stress regulation
🧬 Genetic context

Small, targeted changes can have a meaningful impact on mood and resilience.
💬 Curious how serotonin, gut health, inflammation, or genetics may be affecting you?
Drop your questions below, we’re here to help.

16/12/2025

🌞 Wellness Wednesday: Sydney Summer Stress Is Real (And It’s Not Just the Heat)

Sydney summer looks beautiful on the outside…
But inside, many people are feeling wired, tired, irritable, foggy, and overstimulated 😵‍💫

Heat, humidity, long days, end-of-year pressure, and constant social plans all place extra demand on your nervous system, detox pathways, and hydration status, especially if you have MTHFR or other methylation variants.

🔥 Why Summer Can Feel Hard on the Body
☀️ Heat + humidity increase fluid and mineral loss
🧠 Overstimulation (noise, crowds, screens, social events) raises cortisol
💦 Dehydration worsens fatigue, headaches, and anxiety
🧬 Detox pathways work harder in summer → more nutrient demand
😴 Poor sleep from heat disrupts mood and recovery

Result?
More burnout, more brain fog, less resilience — even when life “should” feel lighter.

💛 Sydney-Friendly Summer Wellness Reset
Try these simple, realistic supports:
💧 Hydrate smarter
Add electrolytes or mineral-rich foods (leafy greens, avocado, coconut water).

🌿 Support methylation & detox
Think folate-rich greens, adequate protein, magnesium, and gentle liver support.

🧘‍♀️ Protect your nervous system daily
Even 5 minutes of breathwork, stretching, or barefoot grounding helps.

😴 Prioritise calm, consistent sleep
Lower lights earlier, keep evenings calm, and cool the room if possible.

🚫 Do less, on purpose
Summer doesn’t need to be busy to be meaningful.

✨ Wellness isn’t about pushing harder; it’s about adapting to your environment.
How is Sydney's summer affecting you right now?

15/12/2025

🧬 Is MTHFR linked to cancer risk?
Yes, but not in the way social media often claims.

MTHFR variants don’t “cause” cancer.
They influence how well your body methylates DNA, repairs damage, and maintains genomic stability, and that influence depends heavily on context.

📍 Folate status
📍 Alcohol intake
📍 Ethnicity
📍 Tumour biology
📍 Overall metabolic load

In some populations, specific variants increase risk.
In others, they appear neutral — or even protective.

💡 The real takeaway?
Genes load the gun. The environment pulls (or disarms) the trigger.

This is why one-size-fits-all advice fails — and why personalised nutrition and genomics matter.

🔖 Save this for reference
💬 Share with someone who’s been scared by oversimplified MTHFR claims

🔍 Reference
Araszkiewicz, A.F., Jańczak, K., Wójcik, P., Białecki, B., Kubiak, S., Szczechowski, M., & Januszkiewicz-Lewandowska, D. (2025). MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications—A Review. Genes, 16. DOI:10.3390/genes16040441

14/12/2025

🚨 STOP SCROLLING 🚨
Mindful Monday (Read This Before You Keep Going)

If your body feels tired but your mind won’t switch off.
This is your sign to pause.

Not later.
Not tonight.
Now.

🌿 The 10-Second Nervous System Check
Ask yourself, no fixing, no judging:
✨ Are my shoulders tense?
✨ Is my jaw clenched?
✨ Am I holding my breath?

Gently release one of them.

That’s mindfulness.
No meditation.
No deep breathing.
Just awareness → relief.

Why this works
🧠 Your brain can’t calm what it hasn’t noticed
🔥 Stress often lives in the body first
🌱 Small awareness shifts create real regulation

You don’t need more motivation.
You need moments of pause built into real life.

💬 Which one did you notice first? Shoulders, jaw, or breath?

11/12/2025

✨ Serotonin isn’t just your “happy hormone”… it’s your BODY’S ENTIRE CONTROL PANEL.
If your serotonin is low, it doesn’t just affect mood; it can ripple through your gut, your sleep, your appetite, your hormones, and even your ability to heal. 😮‍💨

Here’s what serotonin is really doing behind the scenes 👇
🧠 1. Mood & stress resilience
Keeps your emotional “baseline” steady so small things don’t feel huge.

😴 2. Deep, restorative sleep
Serotonin converts to melatonin, which regulates your circadian rhythm.

🍽️ 3. Appetite regulation
Helps control cravings and signals “I’m satisfied.”

🥦 4. Gut function
95% of serotonin is made in your gut! No wonder your mood and digestion are linked.

🩹 5. Healing & tissue repair
Supports clotting, inflammation balance, and cellular recovery.

🔌 6. Nervous system communication
Acts like a messenger between neurons, essential for cognitive function.

🧬 BUT HERE’S THE REAL TWIST…
Your ability to make serotonin depends on:
✔️ Tryptophan intake
✔️ Healthy methylation (MTHFR matters!)
✔️ B6 levels (PLP)
✔️ Gut integrity

If any of these are off, serotonin production plummets, even if your diet is “perfect.”

🍽️ TRY TOP TRYPTOPHAN FOODS:
🐔 Chicken, turkey, lamb
🐟 Wild fish
🌱 Soy, beans, nuts, seeds
🧀 Cheese, eggs, oats
🍌 Banana, pineapple, avocado, potato-with-skin

🌿 Want to understand how your GENES impact serotonin?
We’re breaking down neurotransmitters, methylation, and mood all month. Follow along to learn what your blood tests never explained.

🧬 Practitioners: Join our Functional Genomics Institute Learning Program or our Practitioner Facebook Group to understand this clinically.

📌 SAVE this post to support your patients & your own mental health.

10/12/2025

🌏 Australia, We Need to Talk About Allergies… 🤧🔥

If it feels like everyone you know has allergies now… you’re not wrong.
And the numbers are honestly shocking:

📈 The reality no one is talking about
🇦🇺 20% of Australians are already living with allergic disease.
👶 40–50% of Aussie kids show allergy symptoms before age 4.
🚨 And experts predict a 70% surge by 2050 — that’s 7.7 million people.

Australia officially has one of the highest allergy rates in the world… but why?

🌬️ What’s Driving the Allergy Explosion?

It’s more than just bad luck:
🦠 Hyper-clean living post-COVID → Less germ exposure = overreactive immune system
🏠 Indoor lifestyles → carpets, AC, cleaning products, low airflow
🌳 Low biodiversity → weaker gut microbiome = higher allergy risk
😷 Air pollution & urban environments → irritated airways
💨 Hidden mould & humidity swings → major trigger for histamine overload

This is NOT just seasonal sniffles, it’s an immune system under pressure.

✨ The Good News
You’re not stuck with these symptoms.

If you’re dealing with:
❗constant congestion
❗headaches
❗histamine reactions
❗skin flare-ups
❗unexplained fatigue
…there are solutions deeper than a symptom band-aid.

👉 Our Histamine Relief Packages help you uncover what’s driving your reactions, whether it’s genes, mould, histamine, or your gut.

Take back control of your health:
🔗https://loom.ly/Wd1nMjs

Save this post so you don’t forget, and share it with a parent or friend who needs answers. 💛

09/12/2025

☀️ Low Vitamin D… in Summer?! Yes, it happens more than you think

If you’ve been feeling tired, moody, or not quite yourself lately, it might still be your sunshine vitamin out of balance, even as we head into long, bright Aussie summer days. 💛🌞

Here’s the twist:
Vitamin D deficiency is still common in summer because many of us avoid the sun altogether, stay indoors with the AC on, or apply sunscreen before any natural light hits our skin.

And for those with MTHFR variations?
Vitamin D influences mood, immunity, inflammation, and methylation, making it a key nutrient to monitor.

🌴 Why Vitamin D Drops Even in Summer
☀️ sunscreen blocks UVB (which we need to make Vit D)
🏖️ midday sun feels too harsh
💻 indoor work + weekend errands
🧴 fear of skin damage → overprotection
🌡️ heatwaves = staying inside

☀️ Safe Sun Exposure Without Damaging Your Skin
You don’t need to tan or burn.
Gentle exposure is safest and most effective:
✨ 5–15 minutes of early-morning or late-afternoon sun
✨ No sunscreen for the first few minutes, then apply
✨ Aim for arms, legs, or back (bigger areas = better synthesis)

Pair this with Vitamin D–rich foods:
🐟 salmon + sardines
🍳 egg yolks
🍄 sun-exposed mushrooms
🧀 fortified dairy/plant milks

And if symptoms persist? Testing your levels is the best place to start.

Drop a ☀️ below if you want us to create a post on how to optimise Vitamin D without risking sun damage.

07/12/2025

🌞 Mindful Monday: The “Micro-Pause” That Changes Your Whole Day

Summer can feel fast, with long days, noise, plans, heat, and movement.
Here’s your reminder: you don’t need a whole routine to feel grounded.
You need micro-moments.

🌿 The 5-Second Micro-Pause

Anytime you feel rushed today, try this:
✨ Stop for 5 seconds.
✨ Notice one thing your body appreciates right now.
(A breeze, shade, cold drink, comfy clothes, soft light…)
✨ Let your shoulders soften.

That’s it.
This tiny pause helps reset your stress response and stops your brain from slipping into “auto-overwhelm mode.”
Why it’s powerful

🧠 Gives the prefrontal cortex a break
🔥 Reduces heat-induced irritability
🌡️ Helps regulate sensory overload
🌱 Builds mindfulness without effort

You don’t need more discipline; you need more gentle moments.

What’s one thing your body appreciates today? 🌞

04/12/2025

🌱 Fertility Friday 🌱
Struggling to understand how MTHFR and fertility connect? Here’s the quick, need-to-know guide 👇🧬

🧩 MTHFR is inherited, not random.
You get one copy of the MTHFR gene from each parent.
So if Mum has two variants and Dad has one, you’ll either inherit one or two variants, never zero. 🎲
(And yes… this matters more than many people realise.)

💔 Why it matters for fertility:
Research links MTHFR variants with:
• Recurrent pregnancy loss
• Implantation issues
• Poor methylation → poor egg/sperm quality
• Higher risk of complications if folate pathways are sluggish

🧪 Both partners should be tested.
Fertility isn’t just about one person; methylation is a team sport.

✨ The good news?
You can’t change your genes. …but you can change how they behave.
Nutrients, stress, inflammation, and environment all influence MTHFR activity.

🥦 Already know you have an MTHFR polymorphism?
Focus on:
• Increasing active folate (not folic acid)
• Reducing inflammation
• Supporting detox + stress resilience
• Building a methylation-friendly lifestyle

Every small shift supports a healthier fertility journey and may reduce the risk of miscarriage. 💚

If you’re trying to conceive, this is your sign to check your genes.
Speak to our practitioners & order your MTHFR testing kit today: https://loom.ly/FUWo9Jc

02/12/2025

🌿 Happy Wellness Wednesday 🌸

If life has felt busy, heavy, or a little overwhelming lately… this is your reminder to come back to the basics.
Self-care isn’t indulgent, it’s essential. 💖
And the small things you do daily can completely shift your mood, energy, and MTHFR-related wellbeing.

🌱 1. Nourish early
Start your morning with a nutrient-rich breakfast that fuels your brain and supports methylation.
Think: healthy fats 🥑 + colourful fruit 🍇 + leafy greens 🥬.
Tiny choices → big genetic support.

💧 2. Hydration is a habit
Water boosts energy, detox pathways, and mood.
Add folate-rich foods like broccoli, spinach, herbs & avocado to give your MTHFR pathways some love. 🍀💚

🧘‍♀️ 3. Move or pause - just choose one
A slow walk, gentle stretch, or 5-minute meditation can reset your nervous system instantly.
Yo.
Your mind + body will thank you for even the smallest pause. 🌞

😴 4. Protect your sleep like it’s medicine
Because… it is.
A calm bedtime routine supports hormones, stress recovery, and methylation.
Try soft lighting, magnesium, or a warm herbal tea. 🌙💤

✨ Your Turn:
What’s ONE self-care habit that helps you feel more grounded?
Drop it below so we can inspire each other 💕👇
Let’s build a community that supports wellness. One simple habit at a time. 💚

Address

40 Yeo Street
Crows Nest, NSW
2089

Telephone

+61299081888

Website

http://www.mthfrsupport.com.au/

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Our Story

About MTHFR Support Global: Why did we decide to focus on MTHFR? Well we started to see more and more chronically ill people who had been to doctors , specialists and countless naturopaths and were just not getting the results they should have been. Individuals with a MTHFR mutation or disordered methylation are presenting with cardiovascular disease, chronic inflammation, depression, anxiety, Diabetes, autoimmune conditions, ADD/ADHD, Down's Syndrome, recurrent miscarriage and cancer- to name a few! We need to heal at a cellular level and what we now see is that nutritional methyl donors are restoring our patients health because we are breaking down the obstacles to healing and decreasing inflammation. We work with nutrition, co-factors and substrates required to bring the methylation cycle back into balance to reduce symptoms Our learning always continues and it seems the more we know the more we need to know. We truly believe in a collaborative health care approach. The patient has to come first. We all have to try harder to ensure that sick people get better. We need to think outside the square and all put our heads together to ensure this works. We've seen this every day. We know this works.