25/09/2025
24 September 2025 is World Metastatic Colorectal Cancer (mCRC) Day.
A day dedicated to raising awareness about the most advanced form of bowel cancer and to promoting the importance more tailored care.
Metastatic / Stage 4 bowel (colorectal) cancer is where the cancer has metastasised (spread) to another part of the body - most often the liver or lungs - requiring a more individualised therapeutic approach and increased support.
This year, we again join our international charity partners in raising awareness of biomarkers and their impact on metastatic bowel cancer treatment.
Cancer biomarkers are markers, changes and mutations in genes, DNA or proteins that are found in blood, tissue, or other body fluids and give your specialist / medical team valuable information about the characteristics of your tumour.
Biomarkers can confirm the likelihood of a positive response or side effects to a treatment.
By testing for biomarkers, your medical team can personalise your treatment based on the unique mutations in your tumour and help you avoid unnecessary treatment or side effects.
By identifying tumour-specific mutations, biomarkers can:
+ Predict how your tumour will respond to a specific treatment or not.
+ Help in monitoring if your cancer is coming back after it has been treated.
+ Support in figuring out which clinical trial may be the best fit for you.
Although treatments have advanced more than ever, mCRC still demands greater personalisation and ongoing research. That is why we’re collectively speaking up about the need for:
+ Early access to biomarker testing.
+ Personalised treatment based on genetic markers like RAS, BRAF, and MSI/dMMR.
+ More research, equity, and support for all those affected.
+ Support for patients, caregivers, and families.
For more information on biomarkers visit bowelcanceraustralia.org/biomarkers
You are unique. So is your tumour.
Bowel Cancer Australia Colorectal Cancer Canada Colorectal Cancer Alliance Digestive Cancers Europe - for Patients Fight Colorectal Cancer Global Colon Cancer Association
