Dr. Sandeep Gupta

Dr. Sandeep Gupta Updates from the world of holistic medicine.

Bring your body's terrain back into balance through high-nutrient plant-foods, connection with the earth, letting go of emotional chains and finding spiritual connection within.

18/12/2025

With regards to systemic mold-related illness, key supplements like bentonite and zeolite clays and benfotiamine may help improve elimination of mycotoxins and boost mitochondrial function respectively.

Practitioners can join the pre-launch of the Mold Illness Mastery Course to dive deeper into these essential insights and enhance your health knowledge with Dr. Amy Derksen and myself.

https://lotusinstitutehh.com/mold-illness-mastery/

Use "XMAS25" code for 20% off the full price. Launching in January.

14/12/2025

Ever wondered why symptoms can vary so much with one condition? The chronic activation of mast cells, your body's guard cells, might be the answer. These cells adapt to their environment, creating diverse responses and therefore symptoms. All from the response of one cell. Check out Mast Cells Made Simple for further information. 🧐

11/12/2025

Ever felt a worsening of mast cell activation syndrome in response to weather changes? This may be an evolutionary protective response which may be your body's way of interpreting changes as possible threats to be wary of. Dr. Olivia Lesslar dives into the science behind transient receptor ion channels in these types of responses.

Check out Mast Cells Made Simple online course to find out more.

Very interesting data on saunas !
10/12/2025

Very interesting data on saunas !

Sauna is one of the most effective health protocols I've done. Here is everything I've learned; it's the most robust characterization ever produced.

Results:

1) Fifteen sessions of sauna dramatically reduced environmental toxins in my body:

+ 65% drop in 2,4-D
+ 100% drop in MEP
+ 15% drop in MBP
+ 100% drop in MEHP (undetectable post sauna)
+ 56% drop in NAPR
+ 56% drop in HEMA
+ 100% drop in Perchlorate (undetectable post sauna)

2. Sauna eliminated 85% of microplastics from my ej*****te.

Nov 2024:
165 particles/mL
July 2025: 20 particles/mL

Nearly identical drop in my blood same time period:
Oct 2024: 70 particles/mL
May 2025: 10 particles/mL

3. Sauna, without ice on the boys, devastated my fertility markers.

Total Motile Count: –56%
Concentration: –30%
Motility: –50%
Morphology: –48%
Count: –9%

4. Sauna coincided with my fertility markers being at an all-time high. I have more total and motile s***m than 99.6% of men of any age, including men under 25.

+ total count: 600 M
+ concentration: 162 M
+ motility: 55%
+ total motile count: 330M
+ morphology (normal): 10%

We do not know what to make of these improvements. Was it the sauna? Sauna + ice? Ice only? We don't know but we did not identify any other protocols or lifestyle changes during this interval that would plausibly account for the change.

5. My vascular function improved by a ten year reduction in age. Now I have the vascular age of an elite 18-early 20s.

+ Central Systolic Blood Pressure: 96 mmHg
+ Central Pulse Pressure: 20 mmHg
+ Pulse Pressure Amplification: 160%
+ SEVR: 227%
+ Augmentation Pressure: 1 mmHg
+ Augmentation Index Wave: 3%
+ Traditional blood pressure: 107/75 mmHg

6. What type of sauna?
Use a dry sauna with high temperatures between 80-100°C (176 to 212°F) and 5-20% relative air humidity. Aim for the lower end of this spectrum, especially as a beginner. Higher temperatures closer to the boiling point can cause side effects like headaches and severely dried nose and eyes.

Note: Steam baths, hot tubs, and infrared saunas fail to replicate the same effects because they do not allow you to safely reach the required high temperatures and do not induce the same level of sweating, the necessary inverted (skin-to-core) temperature gradient, and the massive re-direction of blood to the skin with resulting vasodilation.

Dry sauna is unique, and very likely superior to wet (steam bath) and infrared saunas. By heating up your skin way faster than your core, dry hot sauna flips your core skin temperature gradient, eliciting the following hormetic benefits:

+ enhanced blood flow: the heart pumps up to 70% more blood, similar to intense aerobic exercise (zone 2-+ increased sweating for detoxification: to maintain a stable core temperature, the skin produces 0.6-1 liter of sweat per hour, facilitating significant detoxification.
+ improved heat tolerance: the body becomes better at handling heat, leading to a lower core body temperature (offering metabolic advantages)
+ safe activation of heat shock proteins: the skin experiences substantial heat shock protein activation, while a modest 1°C increase in core temperature is sufficient to activate these proteins without the risk of hyperthermia.
+ extended Exposure at higher temperatures: dry saunas are more tolerable for longer durations and at higher temperatures, maximizing the benefits.

7. Sauna protocol and frequency
Type: hot dry sauna
Temperature: 176–212°F ( I do 200°F)
Relative air humidity: very low, 5-20%
Duration: 20 min
Frequency: 4–7x a week

8. Heat Protection

If you'd like, you can protect your head from the heat by wearing a sauna hat or wrapping it with a towel (use only cotton or other 100% natural material). You can breathe through a towel or cloth if needed to protect your nose. I am personally fine not doing this.

Most importantly, ice the balls.

Icing the testicles is absolutely required to prevent heat from damaging fertility markers.

+ Ice the te**es during the sauna session.
+ Use a non-toxic, reusable ice pack material.
+ Wear cotton boxers and shorts.
+ Place ice packs in between the boxers and shorts.
+ Keep them in place for the entire session.

Men should care about preserving fertility markers even when they are not trying to conceive. S***m quality is tightly coupled to testicular function, which governs testosterone production, metabolic health, and long term endocrine stability. When fertility parameters decline, the same upstream dysfunction often drives lower testosterone, higher inflammation, and increased cardiometabolic risk.

9. Hydration

Dry sauna induces sweating as part of its beneficial mechanism. Be sure to hydrate properly. In general, you might need to rehydrate with up to 16–32 oz (0.5–1 L) of fluid after a sauna session. Be sure to add electrolytes.

If you want to be precise, measure your sweat amount and electrolytes (saltiness) using a patch (e.g., from Gatorade) to quantify your liquid and electrolyte loss, and rehydrate accordingly. Some people have saltier sweat than others and must ensure they replenish electrolytes as well as water.

My results: my body sweats 18 oz during a 20 min sauna at 200 °F, with a sodium concentration of 25-39 mg/oz. A single sauna session flushes 450–700 mg of sodium out of my body.

#

I wish you all the best in life my friend. A new era or being human is here. One where existence is the highest virtue. Prioritize sleep, daily exercise and eat well and you'll be in a strong position. Try to avoid the bad stuff. Anything that takes away your agency.

Be a warrior and caretaker of existence. Don't Die.

08/12/2025

The symptoms of mast cell activation syndrome are manifestations of your body's persistent attempts to protect you from perceived threats. This can be considered a maladaptive form of an evolutionary proective mechanism. Bringing in a sense of enduring safety is a vital step to recovering.

05/12/2025

Struggling with Mast Cell Activation Syndrome (MCAS)? The symptoms of MCAS can affect virtually any body system and can include burning pain, flushing, fatigue, depression and many more symptoms. It may be that for some, understanding and treating mast cells can create the space needed for healing . 🎙️

Struggling with unexplained symptoms like flushing, fatigue, pain, gut issues or mood changes? 🧠🔥Mast cells may be playi...
03/12/2025

Struggling with unexplained symptoms like flushing, fatigue, pain, gut issues or mood changes? 🧠🔥

Mast cells may be playing a bigger role than you realise. Although intended to be a short-term response, activation of the mast cells can be ongoing when your body is perceived as being under threat from external material, such as chronic infections, toxicity or emotional trauma.

Join Dr Olivia Lesslar and myself for a free webinar: "Why Mast Cells May Be Involved In Your Chronic Symptoms". We will also be offering a special launch discount on our new online course at the end of the call.

You’ll learn what MCAS is, common triggers, and supportive steps that may help calm an overactive system.

Timing:

📅 USA/Canada: Sun 7 Dec – 6pm PST | 8pm CST | 9pm EST

📅 Australia/NZ: Mon 8 Dec – 10am WA | 12pm QLD | 1pm NSW/VIC | 3pm NZ

Perfect for anyone seeking answers, clarity, or a new perspective on chronic symptoms.

Register now: https://offers.lotusholisticmedicine.com.au/webinar-registration-december-2025-142019

03/12/2025

Feeling overwhelmed by mast cell activation syndrome? Overwhelm and confusion can paralyse us from moving forward. The Mast Cells Made Simple course may assist in many possible ways - I explain these possibilities in this clip.

Join Dr Olivia Lesslar and I in unraveling the mystery of mast cell activation. Find out the key steps to recovering from this syndrome and how you can implement them.

29/11/2025

Ever feel like some days you're more resilient than others? 🛡️ Your relationship to potential threats changes depending on the state of your limbic system and the mast cells. Dr Olivia Lesslar and I explain this theory in the new Mast Cells Made Simple Course.

Some great info here on blue blocking glasses from Elliot from EONutrition.   FYI I'm not affiliated with the deal he is...
27/11/2025

Some great info here on blue blocking glasses from Elliot from EONutrition. FYI I'm not affiliated with the deal he is offering. Just love the info.

In this video I discuss the results of a recent study reported by mainstream media which supposedly "proves" that blue blocking glasses are useless. I explai...

I'm very excited to have had this recent discussion with Dr. Paul Taylor, the renowned "psychophysiologist", with a PhD ...
24/11/2025

I'm very excited to have had this recent discussion with Dr. Paul Taylor, the renowned "psychophysiologist", with a PhD in psychology, separate master's degrees in Exercise Science and nutrition and a postgraduate qualification in Neuroscience.

The interview related to my journey into integrative medicine and how this evolutionary process has also led me to start exploring the best possible approaches to . This has led me to now be offering longevity programs, which I'm happy to share more about.

In the meantime please enjoy the podcast, and please leave any thoughts or comments below.

Podcast Episode · Hardiness with Dr Paul Taylor · 07/11/2025 · 43m

🌿 I’m so excited to announce the pre-launch of my upcoming practitioner course in mold-related illness created with Dr. ...
18/11/2025

🌿 I’m so excited to announce the pre-launch of my upcoming practitioner course in mold-related illness created with Dr. Amy Derksen and titled Mold Illness Mastery: Foundations for Clinical Practice.

This course has been years in the making, and I’m thrilled to finally share it with practitioners who are ready to deepen their understanding of mold-related illness.

If you’re a doctor, naturopath, or integrative practitioner looking for more clarity and confidence in recognizing and treating mold as a root cause, this webinar offers a meaningful preview of the full 8-week practitioner course.

In this session, we’ll walk you through:
✨ How to recognize when mold may be impacting your patients
✨ Key schools of thought in treatment
✨ Lab testing, home testing & remediation basics
✨ Foundational principles to help you individualize care with confidence

📅 USA/Canada: Wed, Nov 19 — 5pm PST / 7pm CST / 8pm EST

📅 Australia/NZ: Thu, Nov 20 — 9am WA / 11am QLD / 12pm NSW/VIC / 2pm NZ

🔗 Save your seat today! Sign up here: http://bit.ly/4oR52y4

👇 Comment below if you’re joining or have questions — and don’t forget to follow along for more clinical insights and course updates! 🌱

Also please like our courage page: https://www.facebook.com/moldillnessmastery/

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Sunshine Coast, QLD
4558

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