CLINUVEL PHARMACEUTICALS LTD

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CLINUVEL is a global specialty pharmaceutical group focused on developing and commercialising treatments for patients with genetic, metabolic, systemic, and life-threatening, acute disorders, as well as healthcare solutions for specialised populations.

Peptides are short chains of amino acids, which are the building blocks that make up proteins. Peptides are smaller and ...
09/01/2026

Peptides are short chains of amino acids, which are the building blocks that make up proteins. Peptides are smaller and less complex than large proteins, yet they play essential biological roles.

CLINUVEL’s pharmaceutical development to date has focused on a family of peptides called melanocortins, which all originate from a common precursor called proopiomelanocortin (POMC).
Known physiological activity influenced by melanocortins includes pigmentation, inflammation, energy homeostasis, appetite and sexual function.

Learn more about melanocortins here: https://www.clinuvel.com/pharmaceuticals/the-science/melanocortins/

We are officially counting down the weeks until ! Following the success of our Pavilion of Photomedicine in 2025, we ca...
08/01/2026

We are officially counting down the weeks until !
Following the success of our Pavilion of Photomedicine in 2025, we cannot wait to share what is in store this year’s American Academy of Dermatology meeting in .

From fresh insights to new innovations, we are building something special.

Mark your calendar and watch this space for updates—you won’t want to miss this.

As the festivities approach, CLINUVEL extends its warmest wishes to all who contribute to our mission - including patien...
23/12/2025

As the festivities approach, CLINUVEL extends its warmest wishes to all who contribute to our mission - including patients, partners, researchers, physicians, ambassadors, advocates, shareholders, analysts, the wider community and our global team of CLINUVELLIANs.

Wishing everyone happy holidays and a prosperous new year.

Have you joined CLINUVEL’s Vitiligo Hub?It aims to unite the vitiligo community and provide resources for those living w...
28/11/2025

Have you joined CLINUVEL’s Vitiligo Hub?

It aims to unite the vitiligo community and provide resources for those living with or caring for someone with this autoimmune condition.

Sign up here: https://brnw.ch/21wXTGw

As a biotech company, CLINUVEL’s story is an unconventional one. Our Founder, Dr Philippe Wolgen, joined the Company’s B...
25/11/2025

As a biotech company, CLINUVEL’s story is an unconventional one. Our Founder, Dr Philippe Wolgen, joined the Company’s Board in 2005, and has a few takeaways to share after 20 years of running the Company.

In this WIRED piece, Dr Wolgen discusses his philosophy and approach to having a focused strategy, recruiting talent, and navigating the challenging landscape of the industry.

Read the interview here: https://brnw.ch/21wXNGC

As winter approaches in the Northern Hemisphere, sun protection remains important. Even though the weather is cooler and...
24/11/2025

As winter approaches in the Northern Hemisphere, sun protection remains important. Even though the weather is cooler and the sun feels weaker, ultraviolet (UV) radiation is still present.

UVA rays, which cause photodamage and skin cancer, are present all year and can even pass through clouds and windows.

UVB rays, responsible for sunburn and skin cancer, may be weaker in autumn, but they still contribute to long-term skin damage.
For those with conditions like , daily sun protection is essential since depigmented skin can burn more easily.

CLINUVEL recommends talking to your dermatologist about the best photoprotective regimen for your lifestyle and skin type, keeping in mind that the use of a broad-spectrum SPF sunscreen on exposed areas every day to protect against cumulative UV damage may be needed all year round.

Erythropoietic protoporphyria (EPP) is characterised by intense phototoxic reactions when exposed to visible light sourc...
21/11/2025

Erythropoietic protoporphyria (EPP) is characterised by intense phototoxic reactions when exposed to visible light sources. These debilitating reactions have been described as akin to “lava flowing underneath the skin” and have a significant impact upon quality of life for those living with EPP.

A recent study asked EPP patients about the experience of their most recent phototoxic reaction. Adults reported an average pain score of 7.6 out of 10, and adolescents reported a score of 7.2, with symptoms typically lasting about five days before resolving.

CLINUVEL is committed to advancing care for EPP patients worldwide, helping them receive the treatment they urgently need to reduce the impact of phototoxic reactions and improve daily life.

CLINUVEL’s Patient Assistance Program (PAP) helps eligible patients with erythropoietic protoporphyria (EPP) in the USA ...
11/11/2025

CLINUVEL’s Patient Assistance Program (PAP) helps eligible patients with erythropoietic protoporphyria (EPP) in the USA get financial assistance for treatment.

Reach out to our team to find out if you are eligible and begin the application process here: https://scenesse.com/public/patient-assistance-program/

11/11/2025

CLINUVEL’s Managing Director, Dr Philippe Wolgen, together with the Investor Relations team, will attend the Stifel Healthcare Conference in New York this week.

Dr Wolgen will present updates on CLINUVEL’s latest clinical and corporate developments, and the team will participate in one-on-one investor meetings.

Engaging with the investment community remains a key priority for the Company and we look forward to joining leaders from across the healthcare sector at this important event.

A recent publication from China reported on a patient whose severe liver dysfunction appeared before the typical phototo...
10/11/2025

A recent publication from China reported on a patient whose severe liver dysfunction appeared before the typical phototoxic symptoms of erythropoietic protoporphyria (EPP). Tragically, the disease progressed to liver failure within a year.

Because phototoxicity was absent, diagnosis of EPP was delayed until blood testing revealed extremely high levels of free erythrocyte protoporphyrin IX, a molecule that accumulates in EPP patients’ blood and liver.

This case underscores a critical point that EPP should be considered in unexplained liver disease, even without phototoxic symptoms.

Early recognition could make a life-saving difference.

___
Source:
Y. J. Zhang, S. P. Huang, Z. Y. Shang, M. Liu, and C. T. Tu, “Recurrent Liver Dysfunction in Erythropoietic Protoporphyria: A Case With Compound Heterozygous FECH Mutations,” Journal of Digestive Diseases (2025): 1–4, https://doi.org/10.1111/1751-2980.70000.

One global study found that approximately 55% of individuals with vitiligo regularly modify their clothing to conceal af...
05/11/2025

One global study found that approximately 55% of individuals with vitiligo regularly modify their clothing to conceal affected areas. This includes wearing long sleeves, trousers, or additional layers, even in warm weather.

These findings underscore the significant emotional impact vitiligo can have on daily life, self-perception, and social interactions.
Efforts to educate the online community are essential to demystifying vitiligo, reducing the stigma and supporting those living with this autoimmune condition.

CLINUVEL is actively sharing key information about vitiligo and collaborating with creators who live with the condition, empowering them to share their experiences and help others with similar diagnoses.

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535 Bourke Street
Melbourne, VIC
3000

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+61396604900

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