22/01/2026
⚠️Important for all horse owners ⚠️
Take the time to read this information from EVA.
ℹ️ Information for Horse Owners 🐴
From our YM President Dr Jordan Flood
⚠️ THE DANGERS OF NSAID USE IN HORSES ⚠️
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in horses to manage pain and inflammation. Common examples includephenylbutazone (bute) and flunixin (non-selective NSAIDs), and meloxicam andfirocoxib (Previcox) (COX-2 selective NSAIDs). While these medications are very effective, they are not without risk.
NSAIDs work by inhibiting prostaglandins, which play a role in pain and inflammation - but prostaglandins also have a protective role the stomach, intestines, and kidneys (among others). When these protective effects are inhibited, especially with high doses, prolonged use, or use in susceptible horses, complications can occur. Importantly, horses vary greatly in their sensitivity to NSAIDs, and some may develop adverse effects even when given the correct dose.
🚨 POTENTIAL SIDE EFFECTS 🚨
• Gastric ulceration
Studies show that an overdose of NSAIDs may contribute to ulcer formation, particularly in the glandular portion stomach.
• Kidney injury
NSAIDs can reduce blood flow to the kidneys. Studies have shown horses that are dehydrated prior to NSAID administration of kidney injury, known as 'renal papillary necrosis'.
• Right dorsal colitis
A serious and potentially life-threatening condition that can occur with or without NSAID overdose. It causes ulceration (and often thickening) of the right dorsal colon in the large colon, which can lead to diarrhea, colic, fever and marked protein loss.
A recent Australian study reported mortality rates of up to 42% in affected horses.
✅ WHAT SHOULD I DO? ✅
• Only give NSAIDs under veterinary direction
• Never exceed the prescribed dose or duration
• Do not combine different NSAIDs unless specifically instructed
• Ensure your horse has good access to water and is well hydrated
• Avoid NSAIDs in sick, dehydrated, or inappetent horses without veterinary advice
• Contact your vet immediately if you notice diarrhoea, colic, reduced appetite, lethargy, or weight loss while receiving NSAIDs.
NSAIDs are valuable medications - but they should always be used carefully. If you’re unsure whether an NSAID is appropriate for your horse or how much to give, talk to your veterinarian first 🩺🐴