Perron Institute for Neurological and Translational Science

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Perron Institute for Neurological and Translational Science

Over forty years of medical research - a journey of discovery, success and outcomes www.perroninstitute.org

Perron Institute is a world leader in neurological science and study, a global collaborator, a community campaigner, a research advocate, a futuristic visionary, a progressive, patient-focused organisation and home to Western Australia’s most successful break-through research team. The Perron Institute is an international leader in taking findings from the laboratory and developing advances in neurological care for the benefit of the community. At the cutting edge of neurological research in Perth, Western Australia, the Perron Institute collaborates with scientists and clinicians nationally and internationally. What makes the Institute unique is its connection with the treatment clinics. Our leading neurologists see people with various conditions including stroke, multiple sclerosis and motor neurone disease plus movement disorders including Parkinson’s, essential tremor and dystonia, inflammatory muscle diseases including inclusion body myositis and polymyositis as well as a variety of unusual and rare muscle and nerve diseases. The Perron Institute’s clinics are open from Monday to Friday and provide diagnosis, management and treatments for patients with complex and usually long term, neurological and neuromuscular conditions. Founded in 1982, the Perron Institute for Neurological and Translational Science is the longest established research institute in Western Australia.

18/12/2025

The Perron Institute is delighted that Paul Anderson and Peter Cutler have joined the Board as non-Executive Directors, each with an impressive record of achievement in their fields of expertise.

Paul Anderson has 25 years’ experience in the healthcare industry, with a focus on developing medical products and the translation of intellectual property to address unmet clinical needs. As Managing Director and co-founder of Orthocell Ltd, a publicly listed regenerative medicine company, he leads the development and commercialisation of advanced cellular therapies and collagen scaffold technologies targeting musculoskeletal repair.

Peter Cutler brings to the Board over thirty years of senior leadership experience in banking, finance and organisational management across Asia-Pacific, the Middle East and Europe. His career includes regional executive roles with Goldman Sachs and Deutsche Bank, where he advised major corporates and financial institutions on complex acquisitions, long-term capital strategy and bond issuance.

https://www.perroninstitute.org/perron-institute-board-appointments-announced/

18/12/2025

The rapidly evolving field of precision medicine and how it is reshaping the understanding and treatment of motor neurone disease is explored in a recent review published in the high-impact journal Molecular Neurodegeneration. The paper, by lead author Dr Frances (Frankie) Theunissen addresses advances in understanding the complex genetic architecture of amyotrophic lateral sclerosis (ALS), the most common form of MND.

The paper emphasises the importance of understanding population genetics and genetic testing when considering patient selection for clinical studies.

Dr Theunissen is a Fight MND Early Career Research Fellow at The University of Notre Dame Australia and the MND Genetics and Therapeutics Research group based at the Perron Institute, the Personalised Medicine Centre (PMC) Murdoch University, and an affiliate of King's College London.

https://www.perroninstitute.org/wa-researchers-highlight-advances-in-precision-approach-for-treating-mnd/

17/12/2025

Consultant Neurologist Dr Wai (Wayne) Yan Yau (Perron Institute, Sir Charles Gairdner Hospital and The University of Western Australia Medical School), has been awarded a $100,000 grant for research on genetic causes of dystonia in Australian families affected by this severely disabling neurological movement disorder.

The grant was awarded under the 2025-26 WA Government’s Future Health Research and Innovation Fund’s (FHRI) Near Miss Awards: Emerging Leaders Program.

Read more: https://www.perroninstitute.org/innovative-wa-research-on-dystonia-attracts-near-miss-grant/

16/12/2025

The protocol of an Australian-first pilot study based at the Perron Institute which explores the efficacy of personalised antidepressants in young people with major depressive disorder (MDD) has been published.

As well as measuring the effectiveness of a tailored approach for participants aged 16 to 24, the GENE-YD Study will inform the feasibility of a much larger randomised controlled trial in Australia.

The novel approach is published in the BMJ Open journal article PharmacoGENEtics in Youth Depression (GENE-YD) Study protocol: a pilot triple-blinded randomised controlled trial using pharmacogenetics to tailor antidepressant treatment in young Australians, by first author, Brad Roberts, a PhD candidate at the Perron Institute and The University of Western Australia.

The study was funded by the Sarich family and the PGx test kits were funded by the WA Government's Future Health and Innovation Fund’s Innovation Challenge.
https://www.perroninstitute.org/tailoring-antidepressant-treatment-in-young-australians/

15/12/2025

Wishing all of our patients, carers and supporters a restful and Merry Christmas and a Happy New Year.

Our last Clinic this year will be Thursday 18 December and Clinics will recommence from 12 January.

05/12/2025

Professor Allan Kermode, Head of Demyelinating Disease Research, Dr Belinda Kaskow (Research Scientist at Perron Insitute|The University of Western Australia) and Dr Marzena Pedrini (Research Fellow) attended the MS Australia's Progress in MS Research Conference in Brisbane this week.

Dr Kaskow presented a talk titled “Immune Profiling in KIR+CD8+ T cells in Multiple Sclerosis” and spoke at the ACE-MS EBV working group sub-meeting.

Highlights were the opening address by Janine Watson, Lived Experience Expert Panel (LEEP) member; the Health Economic Impact of MS in Australia; and insights of the results of the MS Australia research and advocacy priorities outcomes, which we look forward to sharing.

04/12/2025

Researchers at Curtin Medical Research Institute are currently recruiting for a clinical study investigating a new intervention that may provide pain relief in endometriosis.

If you or someone you know would like to know more about the study, please complete the short pre-screening survey to register your interest. Link here: bit.ly/mmend

03/12/2025

PhD Opportunity:
Advancing non-invasive brain stimulation as a treatment modality for youth with depression and su***de ideation.

We are looking for highly motivated students with a background in psychology and/or neuroscience. Students should have a developed understanding of psychology theories and principles or a working understanding of neuroscience principles at an honours equivalent level. Demonstrated experience and a strong willingness to work with clinical populations is favoured. Students will be trained in the relevant experimental techniques but will also be expected to lead their project and work well in a larger team setting.

A PhD scholarship is available through the Perron Institute for the successful applicant.
Applications close 30 January 2026. Scan the QR code or link for more information. https://ow.ly/OEAk50XB4UC
The University of Western Australia

28/11/2025

The Repetitive Transcranial Magnetic Stimulation (rTMS) clinic is now open.

The clinic is specifically tailored toward youth (individuals between the ages of 15 and 25 years old) with depression or related psychiatric conditions.

To learn more about the clinic, scan the QR code or email tms@perron.uwa.edu.au

24/11/2025

Join the waitlist for our Repetitive Transcranial Magnetic Stimulation (rTMS) clinic, opening in late 2025/2026.

To join the list and learn more about the clinic, please scan the QR code or contact us via email at tms@perron.uwa.edu.au

We look forward to welcoming you.

21/11/2025

Four of our researchers were fortunate to receive travel awards at the Business Events Perth Aspire Award Breakfast on Thursday.

Dr Julie Brose was awarded the Business Events Perth Perron Institute Aspire Award to attend the World Federation of Occupational Therapists in Bangkok in 2026. Dr Brose is a a qualitative postdoctoral research fellow whose research at Perron Institute|The University of Western Australia, focuses on gaining a deeper understanding of the lived experiences of people living with life-limiting illnesses, and the families and professionals who support them.

Dr Jessica Cale (Molecular Therapies Research Group at Perron Institute|Murdoch University) and Dr Jun Yuan (Bone and Brain Axis Research Group at Perron Insitute|UWA) were jointly awarded a Business Events Perth Early-Mid Career Researcher Aspire Award.

Both Jessica and Jun will attend the International Oligonucleotide Therapeutics Society Meeting in 2026.

Dr Yuval Gurfinkel (Motor Neurone Disease and Therapeutics Research Group at Murdoch Uni|Perron Institute), was awarded the Business Events Perth Murdoch University Aspire Award to attend the 37th International Symposium on ALS/MND in the Netherlands in 2026.

20/11/2025

People with multiple sclerosis (MS) often experience lower bone density and earlier onset of Osteoporosis, increasing the risk of falls and/or fractures. The STRONG-MS study is evaluating a High-Intensity Resistance and Impact Training (HiRIT) program, to see whether it can improve bone health, muscle strength, mobility, and quality of life in people with MS. Over the course of 12-months, free exercise sessions will be attended twice-weekly, each lasting 30-minutes.

Click here for eligibility criteria and more information: https://www.perroninstitute.org/clinics/clinical-trials/strong-ms-study/

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https://perroninstitute.org/

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Leading a new era of discovery

The Perron Institute is an international leader in taking findings from the laboratory and developing advances in neurological care for the benefit of the community. Our researchers and clinicians develop treatments for people living with a range of debilitating conditions, including muscular dystrophy, stroke, Parkinson’s, multiple sclerosis, motor neurone disease and epilepsy. At the cutting edge of neurological research in Perth, Western Australia, the Perron Institute collaborates with scientists and clinicians nationally and internationally.

What makes the Institute unique is its connection with the treatment clinics. Our leading neurologists see people with various conditions including stroke, multiple sclerosis and motor neurone disease plus movement disorders including Parkinson’s, essential tremor and dystonia, inflammatory muscle diseases including inclusion body myositis and polymyositis as well as a variety of unusual and rare muscle and nerve diseases. Our clinic service has expanded to include a post-stroke/cerebral palsy spasticity clinic and the first epilepsy & pregnancy clinic in Western Australia has been established.

The Perron Institute’s clinics are open from Monday to Friday and provide diagnosis, management and treatments for patients with complex and usually long term, neurological and neuromuscular conditions. Our leading consultant neurologists treat people living with Parkinson’s, motor neurone disease, multiple sclerosis, myositis and post-stroke.

Founded in 1982, the Perron Institute for Neurological and Translational Science is the longest established research institute in Western Australia.

Perron Institute for Neurological and Translational Science

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