31/10/2025
SAMe for Perimenopausal Migraines
If your migraines have worsened during perimenopause, supporting your body’s detox pathways can make a big difference.
One of my favourite tools for this is SAMe (S-adenosylmethionine) — a compound your body naturally makes to help metabolise histamine and detoxify excess estrogen.
When estrogen spikes or isn’t cleared efficiently, histamine often rises too, and that combination can trigger headaches, irritability, and disrupted sleep.
By helping your liver process both more effectively, SAMe supports smoother hormonal balance and reduces the intensity and frequency of these hormone-related migraines.
It’s a beautiful example of how addressing the root cause can bring real relief.
Got any questions? Drop them below in the comments 👇