15/03/2026
Breast cancer and the BRCA1 and BRCA2 genes became widely known after Angelina Jolie spoke publicly about her testing.
But many people still don’t fully understand what these genes actually do.
BRCA genes are tumour suppressor genes.
Every day, cells in your body experience DNA damage.
Normally, BRCA proteins help recognise and repair this damaged DNA before it develops into cancer.
When BRCA mutations are present, this repair system does not function as effectively.
That means supporting DNA protection and repair pathways becomes even more important.
This includes looking beyond just BRCA and considering other genes involved in tumour suppression and DNA repair, such as Quinone Reductase (NQO1) and TP53.
Understanding these pathways can help guide more personalised prevention strategies.
Because genetics isn’t just about risk - it’s about knowing where to focus your prevention efforts.