06/04/2026
If you're taking pramipexole for restless legs, you need to know what's changed.
New RLS treatment guidelines have changed how we approach restless legs. Dopamine agonists — once the go-to treatment — are no longer recommended for routine use due to risks of augmentation and impulse control disorders. First-line treatment is now gabapentinoids, with iron optimisation as the foundation for everyone. I've updated my comprehensive guide to reflect the latest evidence.
👉 https://sleephub.com.au/treatment-for-restless-legs-syndrome/
Latest RLS treatment options based on updated 2025 guidelines. Why dopamine agonists are no longer recommended and the growing role of iron, gabapentinoids, and opioids.