09/01/2026
I often recommend creatine to my perimenopausal and menopausal clients for the brain and mitochondrial benefits—and younger women who train hard or are looking to improve focus, strength, and overall output.
A concern that occasionally comes up is kidney function testing, specifically creatinine levels showing slightly out of range for women taking creatine.
It’s important to understand that creatinine is a normal metabolite of creatine. When someone supplements with creatine, higher creatinine levels on blood work are expected and not inherently harmful. Higher creatinine levels in helathy individuals simply reflects increased creatine turnover.
Bottom line:
✔️ Healthy women supplementing with standard doses of creatine (3-5 g) do not show evidence of kidney damage in research.
✔️ Elevated creatinine in bloodwork with creatine use is expected and not proof of kidney injury.
✔️ If someone does have existing kidney disease, creatine is not usually recommended
This is general information and not individual medical advice