22/06/2025
What is exciting about this discovery, is its another layer, of supportive proof of the failed Amyloid plaque Hypothesis - for 30yrs and >3000 failed clinical trials and one brain bleeding, dubiously pushed through FDA drug, supposedly targeting amyloid, is all we have to show for decades of wasted research on one single area of 'thought' - meanwhile loved ones continue to die from this and women make up 80% of Alzheimers cases - suggesting hormone link, but be buggered trying to find funding to research any links, if they have nothing to do with amyloid- flawed system.
My findings sifting through the research for nearly a decade - amyloid is 'at times' at the scene of the crime, but it is most certainly not the culprit and NO ONE has explained why amyloid is present in healthy brains natural COD, without Alzheimers and also NOT present in all Alzheimer's cases - failed research system, failed funding and support for a bogus, flawed premise. Entirely possible amyloid increases to try and protect the body from the culprit - which is a multifaceted culprit, perfect storm of viral, hormonal, chronic inflammation, reduction gut bacteria species, increase detrimental bacteria (gum disease, herpes simplex), poor lipid and nutrient absorption, diabetes type 3, throw in some familial genes and epigenetic influences and you have COD
"A new study has revealed a surprising way to reverse memory loss linked to both aging and Alzheimer’s disease—without touching the brain’s notorious beta-amyloid plaques. Researchers in Brazil found that a protein called hevin, which is naturally released by brain support cells known as astrocytes, was able to reverse cognitive decline in mice, offering a new way to think about how dementia works and how it might be treated in the future.
Astrocytes aren’t as famous as neurons, but they’re essential. They support brain function by helping neurons connect and communicate, and they release important substances like hevin to help regulate this process. In this study, scientists noticed that levels of hevin were much lower in the brains of people and mice with Alzheimer’s disease. This led them to test whether increasing hevin could protect or even restore brain function.
By boosting hevin levels in the brains of aging and Alzheimer’s-prone mice, the researchers saw improvements in memory and learning. The results showed that the mice performed better on cognitive tasks—even though the buildup of beta-amyloid plaques, long thought to be a key cause of Alzheimer’s, remained unchanged."
Brazilian researchers found that boosting the synthesis of hevin, a glycoprotein naturally secreted by astrocytes, led to enhanced neuronal connectivity in rodents. In Brazil, researchers from the Federal University of Rio de Janeiro (UFRJ), along with collaborators from the University of SĂŁo Pau
