19/11/2023
Intracytoplasmic s***m injection (ICSI)
What is ICSI?
ICSI is a fertility treatment that involves injecting a single s***m cell directly into the cytoplasm of an egg cell. This procedure is a type of in vitro fertilization (IVF), which is a process that helps couples with infertility conceive a child.
How does ICSI work?
The ICSI procedure is typically performed as part of a larger IVF cycle. The first step in the IVF process is to stimulate the ovaries to produce multiple eggs. This is done by administering fertility medications. Once the eggs are mature, they are retrieved from the woman's ovaries using a procedure called follicular aspiration.
The retrieved eggs are then taken to an embryology laboratory. In the laboratory, the eggs are carefully prepared for fertilization. The s***m cells are also prepared, and a single s***m cell is selected for injection into each egg cell.
The ICSI procedure is performed using a microscope and a specially designed instrument called a micromanipulator. The micromanipulator is used to hold the egg cell in place and to inject the s***m cell into the cytoplasm of the egg cell.
Once the s***m cell has been injected, the egg cells are carefully monitored for signs of fertilization. If fertilization occurs, the fertilized egg cells are allowed to develop into embryos.
The embryos are then cultured in the laboratory for 2-5 days. After this time, one or more embryos are selected for transfer to the woman's uterus.
Who is a good candidate for ICSI?
ICSI is a good option for couples with infertility who have one of the following conditions:
Male infertility: ICSI can be used to overcome a variety of male infertility factors, including low s***m count, poor s***m motility, and abnormal s***m morphology.
Female infertility: ICSI can also be used to treat female infertility factors, such as tubal blockage or ovarian dysfunction.
Previous failed IVF cycles: ICSI may be recommended for couples who have failed to conceive after multiple cycles of traditional IVF.
What are the success rates of ICSI?
The success rates of ICSI vary depending on the underlying cause of infertility. However, in general, the success rates of ICSI are comparable to those of traditional IVF.
A study published in the journal Human Reproduction found that the average live birth rate per embryo transfer for ICSI was 25.2%.
What are the risks of ICSI?
The risks of ICSI are similar to those of traditional IVF. These risks include:
Multiple pregnancy: ICSI increases the risk of multiple pregnancy, which can be associated with complications such as premature birth and low birth weight.
Ectopic pregnancy: ICSI also increases the risk of ectopic pregnancy, which is a pregnancy that occurs outside the uterus.
Ovarian hyperstimulation syndrome (OHSS): OHSS is a condition that can occur in women who undergo ovarian stimulation for IVF. Symptoms of OHSS can include abdominal pain, bloating, and nausea.
What to expect after ICSI
After ICSI, the woman will typically be monitored for pregnancy. If a pregnancy is confirmed, she will receive regular prenatal care.
Conclusion
ICSI is a safe and effective fertility treatment that can help couples with infertility achieve their dream of having a child.
