IREC - UCLouvain

IREC - UCLouvain The Institute of Experimental and Clinical Research conducts research in all areas of clinical and e

11/01/2023

Une équipe internationale conduite par le Pr Olivier Devuyst (UCLouvain et Cliniques universitaires Saint-Luc) et le Dr Eric Olinger (Universités de Zurich et de Newcastle, Cliniques Saint-Luc), a …

04/10/2022

🧬 Brouiller le radar pour empêcher les métastases 🧬

➡ On peut se demander pourquoi un cancer du sein peut métastaser dans le cerveau, les poumons, le foie et dans les os, mais jamais dans le lobe de l’oreille ou dans le gros orteil ?

➡ Pierre Sonveaux, Directeur de Recherches FNRS, Promoteur Welbio et Télévie UCLouvain – Université catholique de Louvain et son équipe publient un nouvel article dans la r***e scientifique "Cancers".

➡ Ils y expliquent qu'ils sont parvenus à identifier un senseur responsable de l’arrêt dans le cerveau des cellules tumorales de cancer du sein, ce qui leur permet de développer des métastases cérébrales.

➡ L’intérêt ? Sans ce senseur, les cellules tumorales ne s’arrêtent pas dans le cerveau et ne développent donc pas de métastases cérébrales.

➡ Si le senseur Cox7b apparaît malheureusement difficile à cibler en thérapie anti-cancéreuse, la compréhension de ce nouveau mécanisme permettra de systématiser la découverte de familles de senseurs et, c’est l’objectif, de trouver in fine des cibles exploitables.

➡ En empêchant la survenue des métastases, les thérapies à visée curative pourraient être utilisées plus longtemps, et les chances de guérison seraient donc accrues.

➕ Plus d'infos : https://www.mdpi.com/2072-6694/14/18/4371

EXIMIOUS is a research project funded by the European Commission’s Horizon 2020 research and innovation programme, that ...
24/01/2022

EXIMIOUS is a research project funded by the European Commission’s Horizon 2020 research and innovation programme, that aims to deliver a new way of assessing the human exposome, i.e., the exposures to environmental factors that one experiences throughout life, and shed light on its association to immune-mediated diseases.
👉We are delighted to invite you to join us online for the second EXIMIOUS Symposium “Immune-mediated diseases: an interplay between environment and genetics”
🧑‍Coordinator : Dr Peter Hoet (KU Leuven)
⚠️ Registrations by 31 January 2022 at : https://us02web.zoom.us/webinar/register/WN_AZV-LK0sSmC_8pa9kMcSeA

Welcome! You are invited to join a webinar: EXIMIOUS Symposium "Immune-mediated diseases: an interplay between environment and genetics". After registering, you will receive a confirmation email about joining the webinar.

27/10/2021
07/09/2021

🆕 Hygieia, c’est parti ! Ce projet novateur a pour objectif de répondre aux énormes défis de la pandémie de Covid-19, mais aussi à d’autres situations pandémiques ou de maladies complexes non-infectieuses.
Cette étude, qui répond à un appel du Covid Solidarity Fund, repose notamment sur le potentiel énorme de l’intelligence artificielle. 👏 Elle est soutenue à hauteur de 2.700.000€ par le mécénat d’entreprise, via la Fondation Saint-Luc.
👉 Plus d’infos sur saintluc.be/hygieia

In a publication in the American Journal of Pathology, researchers from the Cliniques universitaires Saint-Luc and the I...
16/06/2021

In a publication in the American Journal of Pathology, researchers from the Cliniques universitaires Saint-Luc and the IREC - UCLouvain have demonstrated that the placenta is not susceptible to SARS-CoV-2 infection at term. Their findings make the transmission to the neonate unlikely to occur around the delivery and are therefore reassuring for all the pregnant women.

https://ajp.amjpathol.org/article/S0002-9440(21)00243-1/fulltext

Despite occasional reports of SARS-CoV-2 vertical transmission during pregnancy, the question of placental infection and its consequences for the newborn remain questionable. Here, we analyzed the placentas of 31 COVID-19-positive mothers by RT-PCR, immunohistochemistry and in situ hybridization. We...

15/06/2021

Une recherche menée conjointement par des bioingénieurs de l’UCLouvain, spécialistes de la nutrition, et leurs collègues de l’Institut de recherche expérimentale et clinique (Faculté de pharmacie) …

Muscle fat content is strongly associated with NASH https://www.journal-of-hepatology.eu/article/S0168-8278(21)00234-8/a...
10/06/2021

Muscle fat content is strongly associated with NASH
https://www.journal-of-hepatology.eu/article/S0168-8278(21)00234-8/abstract

Muscle composition as a novel non-invasive marker for metabolic diseases? EASL - The Home of Hepatology Cliniques universitaires Saint-Luc IREC - UCLouvain

Studies exploring the relationship between muscle fat content and non-alcoholic fatty liver disease (NAFLD) are scarce. Herein, we aimed to evaluate the association of muscle mass and fatty infiltration with biopsy-assessed NAFLD in patients with obesity.

📣Join us TODAY on YouTube at 4:30 PM 👉https://www.youtube.com/user/universitedelouvain for theFaculty of Medicine & IREC...
19/05/2021

📣Join us TODAY on YouTube at 4:30 PM
👉https://www.youtube.com/user/universitedelouvain for the
Faculty of Medicine & IREC Doctor Honoris Causa Ceremony 📜

The prestigious title will be awarded to three leading personalities in the medical field: Pr Bruno Crestani (Université de Paris and Hôpital Bichat, France); Pr Amit Nathwani (University College London and Royal Free Hospital, UK); Pr Marc Pfeffer (Harvard University and Brigham and Women’s Hospital, USA).

📣Do not miss the last issue of Belgian Research in Europe ! 👉Including an interview to IREC President Pr. Balligand and ...
22/03/2021

📣Do not miss the last issue of Belgian Research in Europe ! 👉Including an interview to IREC President Pr. Balligand and interesting contributions by some of our research groups LTAP, FATH, Contrast Team and Clinical Trial Center.👏👏👏
https://www.belgian-research.eu/

  is a master regulator of cardiac cicatricial   occurring after myocardial infarction. AMPK exerts anti-fibrotic effect...
25/02/2021

is a master regulator of cardiac cicatricial occurring after myocardial infarction. AMPK exerts anti-fibrotic effects by regulating cardiac fibroblast proliferation via a mechanism. A study from IREC - UCLouvain, Pôle de Recherche Cardiovasculaire (Sandrine Horman, Cécile Dufeys), in collaboration with Cliniques universitaires Saint-Luc and KU Leuven, published in Basic Res Cardiol, 2021 https://link.springer.com/article/10.1007/s00395-021-00846-y

We have previously demonstrated that systemic AMP-activated protein kinase α1 (AMPKα1) invalidation enhanced adverse LV remodelling by increasing fibroblast proliferation, while myodifferentiation and scar maturation were impaired. We thus hypothesised that fibroblastic AMPKα1 was a key signallin...

The UCLouvain centre of Allergy, based at Cliniques universitaires Saint-Luc, CHU-UCL Namur and at the Faculty of Medici...
15/12/2020

The UCLouvain centre of Allergy, based at Cliniques universitaires Saint-Luc, CHU-UCL Namur and at the Faculty of Medicine, has been officially recognized as an Excellence center by the World Allergy Organization (WAO). 👏👏 This award, reserved to a few institutions (only 12 in Europe), highlights the excellence of UCLouvain – Université catholique de Louvain and its hospital centers in the field of allergology, a discipline that remains insufficiently recognized in our country. With specialized pulmonologists, dermatologists, ENT and pediatricians, this center offers an integrated care of patients with respiratory, skin, food as well as drug allergies. The UCLouvain center of Allergy also drives cutting-edge research programs at the IREC - UCLouvain institute and offers a specific training of this discipline to future doctors, globally underlying a multidimensional dynamics to improve the quality of care to patients.

https://www.worldallergy.org/wao-centers-of-excellence/europe/louvain-la-neuve-belgium-2020

The Cliniques universitaires Saint-Luc (https://www.saintluc.be/en/index.php), located in the south of Brussels, and Centre Hospitalier Universitaire de Namur – site Godinne located in Wallonia are the two academic hospitals of the Université catholique of Louvain (UCLouvain), Belgium. Those hosp...

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