Néo-Acupuncture Lynn WEI

30/08/2025

' In diseases such as , amyotrophic lateral sclerosis and , sustained perpetuated by activated microglia is a hallmark feature. Moreover, in symptoms, inflammatory mechanisms are also likely to play a substantial role. '

' extracts are used as an accepted treatment option for and indications in different countries as well as for ameliorating cognitive impairment and quality of life in dementia sufferers. a number of different pharmacological activities with potential relevance for the clinical use have been reported from clinical and non-clinical studies, including vasoregulatory activity, improved blood flow, antioxidative activity, reduction in amyloid oligomer and plaque formation and toxicity, improvement of neuroplasticity, increase in neurotransmitter levels and protection against mitochondrial dysfunction. a standardised extract of Ginkgo biloba leaves is a well defined product and contains approximately 24% flavone glycosides (primarily quercetin, kaempferol and isorhamnetin) and 6% terpene lactones (2.8-3.4% ginkgolides A, B and C, and 2.6-3.2% bilobalide). Ginkgolide B and bilobalide account for about 0.8% and 3% of the total extract, respectively. other constituents include proanthocyanadins, glucose, rhamnose, organic acids, D-glucaric and ginkgolic acids. '

Badanjak, K.; Fixemer, S.; Smaji, S.; Skupin, A.; Grünewald, A. The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease. Int. J. Mol. Sci. 2021, 22, 4676.

Thakur, S.; Dhapola, R.; Sarma, P.; Medhi, B.; Reddy, D.H. Neuroinflammation in Alzheimer s Disease: Current Progress in Molecular Signaling and Therapeutics. Inflammation 2023, 46, 1–17.

Merad, M.; Blish, C.A.; Sallusto, F.; Iwasaki, A. The Immunology and Immunopathology of COVID-19. Science 2022, 375, 1122–1127.

Nalbandian, A.; Sehgal, K.; Gupta, A.; Madhavan, M.V.; McGroder, C.; Stevens, J.S.; Cook, J.R.; Nordvig, A.S.; Shalev, D.; Sehrawat, T.S.; et al. Post-Acute COVID-19 Syndrome. Nat. Med. 2021, 27, 601–615.

Huang, S.Y.; Jeng, C.; Kao, S.C.; Yu, J.J.H.; Liu, D.Z. Improved Haemorrheological Properties by Ginkgo Biloba Extract (Egb 761) in Type 2 Diabetes Mellitus Complicated with Retinopathy. Clin. Nutr. 2004, 23, 615–621.

Kellermann, A.J.; Kloft, C. Is There a Risk of Bleeding Associated with Standardized Ginkgo Biloba Extract Therapy? A Systematic Review and Meta-Analysis. Pharmacotherapy 2011, 31, 490–502.

Abdel-Wahab, B.A.; Abd El-Aziz, S.M. Ginkgo Biloba Protects against Intermittent Hypoxia-Induced Memory Deficits and Hippocampal DNA Damage in Rats. Phytomedicine 2012, 19, 444–450.

Luo, Y.; Smith, J.V.; Paramasivam, V.; Burdick, A.; Curry, K.J.; Buford, J.P.; Khan, I.; Netzer, W.J.; Xu, H.; Butko, P. Inhibition of Amyloid-Beta Aggregation and Caspase-3 Activation by the Ginkgo Biloba Extract EGb761. Proc. Natl. Acad. Sci. USA 2002, 99, 12197–12202.

Tchantchou, F.; Xu, Y.; Wu, Y.; Christen, Y.; Luo, Y. EGb 761 Enhances Adult Hippocampal Neurogenesis and Phosphorylation of CREB in Transgenic Mouse Model of Alzheimer’s Disease. FASEB J. 2007, 21, 2400–2408.

Kehr, J.; Yosh*take, S.; Ijiri, S.; Koch, E.; Nöldner, M.; Yosh*take, T. Ginkgo Biloba Leaf Extract (EGb 761®) and Its Specific Acylated Flavonol Constituents Increase Dopamine and Acetylcholine Levels in the Rat Medial Prefrontal Cortex: Possible Implications for the Cognitive Enhancing Properties of EGb 761®. Int. Psychogeriatr. 2012, 24 (Suppl. 1), S25–S34.

Abdel-Kader, R.; Hauptmann, S.; Keil, U.; Scherping, I.; Leuner, K.; Eckert, A.; Müller, W.E. Stabilization of Mitochondrial Function by Ginkgo Biloba Extract (EGb 761). Pharmacol. Res. 2007, 56, 493–502.

24/08/2025

Épisode de l’émission · JAMA Editors' Summary · 22/08/2025 · 12 min

19/08/2025

' Combinations of with DNA Vaccination.

The combination of chemotherapy with immunotherapy (including DNA vaccination) might represent a potential strategy for cancer treatment because certain chemotherapy-based cancer treatments may activate the immune system against the tumor through several molecular and cellular mechanisms and reduce tumor. It has been described that some molecules have the ability to increase vaccine-induced immunity against cancer. Furthermore, bulky tumor growth was inhibited by EGCG in combination with a genetic vaccine while a multimodal treatment against progressive tumors based on apigenin and genetic vaccines demonstrated immunotherapeutic effects. Nevertheless, very few works describe the effects of combined used of natural compounds with HPV genetic vaccination. The immunomodulatory properties of G. uralensis polysaccharides were investigated in combination with HPV DNA vaccination. G. uralensis polysaccharides injection had no side effect on mice, enhancing the immunity of mice and the antigen-specific cellular and humoral immune responses induced by HPV DNA vaccine. ( ) and its components, like monoterpene aldehyde and carotenoids derived from dry stigmas, have been suggested as favorable candidates for cancer prevention. The potential use of saffron derivatives such as extracts or purified components-carotenoids derived from dry stigmas of pure saffron alone or combined with genetic vaccination, was investigated on HPV-related experimental tumor. The in vitro cytotoxic and apoptotic effects of aqueous saffron extract and its components picrocrocin, a monoterpene aldehyde and crocin, a natural carotenoid, were assessed in malignant (TC-1) and non-malignant (COS-7) cell lines. Unlike most carotenoids, that have a limited therapeutic use because of their insolubility in water, glycosylated molecules like crocin and picrocrocin (due to their glycosylated state) are soluble and highly cytotoxic on malignant cells; they therefore represent the most appropriate saffron derivatives for cancer treatment. The anti-tumor activity of a genetic vaccine candidate and saffron components were evaluated in vivo; mice were challenged subcutaneously with TC-1 tumor cells and on day 3 and 17 they were Cancers 2020, 12, 3101 25 of 38 immunized with E7-NT (gp96) DNA. Crocin, , and saffron extract were given orally at the time of the initial DNA immunization and for the next 16 days. While the multimodal treatment using DNA vaccine along with picrocrocin augmented the anti-tumor effects of picrocrocin, the combination of DNA vaccine with saffron extract and crocin at certain concentrations could not potentiate protective and therapeutic effects compared to mono-therapies for the control of TC-1 tumors. In particular, oral administration of crocin resulted in complete tumor regression, while it did not increase DNA vaccine-mediated anti-tumor effects. These data are apparently in contrast to those from other studies about combination of chemotherapy with EGCG, and followed by immunotherapy with DNA vaccination. This highlights that, for proper evaluation of synergist effects of chemo-immunotherapy, the selection of the optimal dose and treatment schedule still represents a critical challenge to overcome. '

Franconi R, Massa S, Paolini F, Vici P, Venuti A. Plant-Derived Natural Compounds in Genetic Vaccination and Therapy for HPV-Associated Cancers. Cancers (Basel). 2020 Oct 23;12(11):3101.

' One milliliter of tincture was diluted with 9 ml of purified water and placed into the va**na with the hips raised so that the tincture could fully cover the cervix and va**na for 20 minutes. The solution was used once per day for 10 days, which was considered to be one course. Then, was applied at intervals of 3 days to promote repair. The above treatment was repeated for 6 courses. If the patient encountered a menstrual period during the intervention, the intervention was postponed. Traditional Chinese medicine pays more attention to the overall and macro roles than to the molecular and cellular levels. The Chinese multiherb extracts we used in this study were prepared from nine traditional Chinese medicines, including Java brucea, Fritillaria thunbergii (FT), Scutellaria barbata, Sophora flavescens, arnebia, Radix isatidis, Radix scutellariae and saponin thorn. This formula is based on the theory of traditional Chinese medicine, playing the role of several main drugs and highlighting the synergy of various traditional Chinese medicines. The overall function of this prescription in traditional Chinese medicine is antiviral, antitumor, antiinflammatory, and corrosive; it clears away toxins, resists bacteria, and dispels dampness. '

Chen LM, Cong Q, Wu D, Chen Y, Qiu LH, Hong ZB, Yang YB, Xu L, Wang LF, Huang LX, Li WR, Tang JP, Cao YG, Sui L. A prospective multicentre controlled study of Gaoweikang (Chinese multiherb extract-based tincture) used in high-risk HPV infections. Eur Rev Med Pharmacol Sci. 2023 Oct;27(19):8985-8992.

18/08/2025

' The study revealed that a total of 41 gut bacterial taxa have causal associations with insomnia. '

There is a bidirectional relationship between gut bacteria and insomnia, new research suggests. But some are challenging the investigators’ assertion that the link is causal.

11/08/2025

TIPSS.

10/08/2025

That reminds me a national research in China for seniors. https://journals.sagepub.com/doi/epub/10.1177/0145561319842511

Raymond MJ, McColloch NL, Hatcher JL. Upper Esophageal Sphincter Dilation for Recalcitrant Dysphagia Secondary to . Ear Nose Throat J. 2019 Oct-Nov;98(9):NP142-NP143.

Kidambi TD, Schmajuk G, Gross AJ, Ostroff JW, Terdiman JP, Lee JK. is of low yield in the identification of neoplasia in patients with dermatomyositis: A cross-sectional study. World J Gastroenterol. 2017 Jul 14;23(26):4788-4795.

Pozharashka J, Dourmishev L, Rusinova D, Balabanova M, Miteva L. Paraneoplastic Dermatomyositis in a Patient with Metastatic Carcinoma. Acta Dermatovenerol Croat. 2020 Aug;28(2):120-122.

Laidler NK. Dermatomyositis as a paraneoplastic phenomenon in oesophageal cancer. BMJ Case Rep. 2018 Dec 7;11(1):e227387. doi: 10.1136/bcr-2018-227387.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7193243/

09/08/2025

Painful ? some can ease the .

09/08/2025

China government prohibits the < Deep Cervical Lymphatic Vessel/Lymph Node-Venous Anastomosis in the Treatment of Alzheimer’s Disease >.

09/08/2025

Comment prévenir la d’ , les etc grâce aux méthodes ( des méthodes de longue vie très prisées par les établissements de )? Je vous partagera les techniques pour votre et le protéger des dépôts de ( en lien avec la maladie ) : + + , pour vous connaîtrez le geste indispensable pour revitaliser les organes responsables de la maladie d'Alzheimer.

08/08/2025

Carvi aetheroleum

06/08/2025

Juxtaposition, the Western modern lines and the .

30/07/2025

now, and its explanation in archive thousands years ago.

傷寒論註, 辨太陽病脈證并治中篇 : 太陽病，頭痛發熱，身疼腰痛，骨節疼痛，惡風無汗而喘者，麻黃湯主之。

https://www.mayoclinic.org/zh-hans/diseases-conditions/infectious-diseases/expert-answers/what-is-chikungunya-fever/faq-20109686